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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 3 complex
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Accession:GO:0005852 term browser browse the term
Definition:A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
Synonyms:exact_synonym: eIF-3;   eIF3
 only_in_taxon: NCBITaxon:2759 ! Eukaryota



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eukaryotic translation initiation factor 3 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked colocalizes_with
part_of
ISO
IEA
(PMID:18628297)
GO_REF:0000107
RGD
Ensembl
PMID:18628297 GO_REF:0000107 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A part_of
located_in
ISO
ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
GO_REF:0000024
(MGI:3843422|PMID:17581632)
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 GO_REF:0000024 MGI:3843422 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B part_of
located_in
IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:17322308)
(MGI:3843422|PMID:17581632)
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:8995410)
UniProt
RGD
PMID:8995410 PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 More... GO_REF:0000024 MGI:3843422, RGD:13792537 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C part_of
located_in
ISO
IBA
ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
(MGI:3843422|PMID:17581632)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:21873635 GO_REF:0000024 MGI:3843422, RGD:13792537 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D part_of
located_in
IBA
ISO
ISS
PMID:21873635
(PMID:17322308)
(MGI:3843422|PMID:17581632)
GO_REF:0000024
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:27462815)
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:27462815 More... GO_REF:0000024 MGI:3843422, RGD:13792537 NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E part_of
located_in
ISS
ISO
IBA
GO_REF:0000024
(MGI:3843422|PMID:17581632)
(PMID:17322308)
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:9295280)
PMID:21873635
UniProt
RGD
PMID:9295280 PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 More... GO_REF:0000024 MGI:3843422, RGD:13792537 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
JBrowse link
G Eif3e-ps1 eukaryotic translation initiation factor 3 subunit E, pseudogene 1 part_of
located_in
ISO (PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773), (PMID:9295280)
(MGI:3843422|PMID:17581632)
RGD PMID:9295280 PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 MGI:3843422 NCBI chr 7:75,257,366...75,265,601 JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F part_of
located_in
ISO (PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
(MGI:3843422|PMID:17581632)
RGD PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 MGI:3843422 NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G part_of
located_in
ISO
ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
(MGI:3843422|PMID:17581632)
GO_REF:0000024
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 GO_REF:0000024 MGI:3843422 NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H part_of
located_in
IBA
ISO
ISS
PMID:21873635
(PMID:17322308)
(MGI:3843422|PMID:17581632)
GO_REF:0000024
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:21873635 GO_REF:0000024 MGI:3843422, RGD:13792537 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I part_of
located_in
ISO
ISS
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
GO_REF:0000024
(MGI:3843422|PMID:17581632)
RGD
UniProt
PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 GO_REF:0000024 MGI:3843422 NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
JBrowse link
G Eif3j eukaryotic translation initiation factor 3, subunit J part_of
located_in
IBA
ISO
ISS
PMID:21873635
(PMID:17322308)
GO_REF:0000024
(PMID:17322308), (PMID:18599441)
RGD
UniProt
PMID:17322308 PMID:18599441 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953
JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K part_of
located_in
IBA
ISO
PMID:21873635
(PMID:17322308)
(MGI:3843422|PMID:17581632)
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
RGD PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:21873635 MGI:3843422, RGD:13792537 NCBI chr 1:84,260,125...84,270,051
Ensembl chr 1:84,259,673...84,270,302
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L part_of
located_in
IBA
ISO
PMID:21873635
(PMID:17322308)
(MGI:3843422|PMID:17581632)
(PMID:17322308), (PMID:17581632), (PMID:18599441), (PMID:25849773)
RGD PMID:17322308 PMID:17581632 PMID:18599441 PMID:25849773 PMID:21873635 MGI:3843422, RGD:13792537 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M part_of
located_in
ISO
IBA
(PMID:17322308), (PMID:18599441), (PMID:25849773)
PMID:21873635
RGD PMID:17322308 PMID:18599441 PMID:25849773 PMID:21873635 RGD:13792537 NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392
JBrowse link
G LOC100365062 eukaryotic translation initiation factor 3, subunit 6 48kDa-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:73,774,491...73,775,984
Ensembl chr 1:73,774,487...73,776,003
JBrowse link
eukaryotic translation initiation factor 3 complex, eIF3e term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif3a eukaryotic translation initiation factor 3, subunit A part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
JBrowse link
G LOC100365062 eukaryotic translation initiation factor 3, subunit 6 48kDa-like part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:73,774,491...73,775,984
Ensembl chr 1:73,774,487...73,776,003
JBrowse link
eukaryotic translation initiation factor 3 complex, eIF3m term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif3a eukaryotic translation initiation factor 3, subunit A part_of IBA
ISO
PMID:21873635
(MGI:5543727|PMID:24003236)
RGD PMID:24003236 PMID:21873635 MGI:5543727, RGD:13792537 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B part_of ISO (MGI:5543727|PMID:24003236) RGD PMID:24003236 MGI:5543727 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C part_of ISO (MGI:5543727|PMID:24003236) RGD PMID:24003236 MGI:5543727 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D part_of ISO (MGI:5543727|PMID:24003236) RGD PMID:24003236 MGI:5543727 NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F part_of IBA
ISO
PMID:21873635
(MGI:5543727|PMID:24003236)
RGD PMID:24003236 PMID:21873635 MGI:5543727, RGD:13792537 NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H part_of ISO (MGI:5543727|PMID:24003236) RGD PMID:24003236 MGI:5543727 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I part_of IBA
ISO
PMID:21873635
(MGI:5543727|PMID:24003236)
RGD PMID:24003236 PMID:21873635 MGI:5543727, RGD:13792537 NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M part_of ISO (MGI:5543727|PMID:24003236) RGD PMID:24003236 MGI:5543727 NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19187
    protein-containing complex 5925
      eukaryotic translation initiation factor 3 complex 16
        eukaryotic translation initiation factor 3 complex, eIF3e 3
        eukaryotic translation initiation factor 3 complex, eIF3m 8
Path 2
Term Annotations click to browse term
  cellular_component 19187
    cellular anatomical entity 18928
      intracellular anatomical structure 14074
        cytoplasm 11200
          eukaryotic translation initiation factor 3 complex 16
            eukaryotic translation initiation factor 3 complex, eIF3e 3
            eukaryotic translation initiation factor 3 complex, eIF3m 8
paths to the root