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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 2B complex
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Accession:GO:0005851 term browser browse the term
Definition:A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
Synonyms:exact_synonym: eIF-2B;   eif2B


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eukaryotic translation initiation factor 2B complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha part_of IDA
IEA
ISS
ISO
IBA
GO_REF:0000107
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
PMID:21873635
Ensembl
UniProt
RGD
PMID:11323413 PMID:15060152, PMID:9631509, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:11041878, RGD:13792537 NCBI chr12:37,444,136...37,452,391
Ensembl chr12:37,444,072...37,465,398
JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta part_of IDA
IBA
ISO
ISS
IEA
PMID:21873635
(PMID:11323413), (PMID:15060152)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:11323413 PMID:15060152, PMID:9631509, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:11041878, RGD:13792537 NCBI chr 6:109,044,830...109,051,254
Ensembl chr 6:109,043,880...109,051,253
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma part_of IDA
IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
UniProt
RGD
PMID:11323413 PMID:15060152, PMID:9139680, PMID:21873635, PMID:9631509, PMID:9582312 GO_REF:0000024, RGD:1581073, RGD:13792537, RGD:11041878, RGD:1581075 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta part_of IDA
IEA
NAS
ISO
ISS
GO_REF:0000107
PMID:9582312
(PMID:11323413), (PMID:15060152)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11323413 PMID:15060152, PMID:9139680, PMID:9582312, PMID:9631509, PMID:9582312 GO_REF:0000024 GO_REF:0000107, RGD:1581073, RGD:1581075, RGD:11041878, RGD:1581075 NCBI chr 6:26,546,917...26,552,474
Ensembl chr 6:26,546,924...26,552,430
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon part_of IDA
IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
UniProt
RGD
PMID:11323413 PMID:15060152, PMID:9139680, PMID:9582312, PMID:9631509, PMID:21873635 GO_REF:0000024, RGD:1581073, RGD:1581075, RGD:11041878, RGD:13792537 NCBI chr11:84,080,273...84,090,259
Ensembl chr11:84,080,273...84,090,259
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha part_of IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11323413)
UniProt
RGD
PMID:11323413, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      eukaryotic translation initiation factor 2B complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11416
          eukaryotic translation initiation factor 2B complex 6
paths to the root