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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 2B complex
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Accession:GO:0005851 term browser browse the term
Definition:A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
Synonyms:exact_synonym: eIF-2B;   eif2B



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eukaryotic translation initiation factor 2B complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha part_of IDA
IPI
IEA
ISS
ISO
IBA
PMID:9139680
GO_REF:0000107
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
PMID:21873635
Ensembl
UniProt
RGD
PMID:11323413 PMID:15060152 PMID:9631509 PMID:9139680 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:11041878, RGD:1581073, RGD:13792537 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta part_of IDA
IPI
IBA
ISO
ISS
IEA
PMID:9139680
PMID:21873635
(PMID:11323413), (PMID:15060152)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:11323413 PMID:15060152 PMID:9631509 PMID:9139680 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:11041878, RGD:1581073, RGD:13792537 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma part_of IDA
IPI
IBA
ISS
ISO
PMID:9139680
PMID:21873635
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
UniProt
RGD
PMID:11323413 PMID:15060152 PMID:9139680 PMID:9139680 PMID:21873635 More... GO_REF:0000024, RGD:1581073, RGD:1581073, RGD:13792537, RGD:11041878, RGD:1581075 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta part_of IDA
IPI
NAS
ISO
ISS
PMID:9139680
PMID:9582312
(PMID:11323413), (PMID:15060152)
GO_REF:0000024
RGD
UniProt
PMID:11323413 PMID:15060152 PMID:9139680 PMID:9139680 PMID:9582312 More... GO_REF:0000024, RGD:1581073, RGD:1581073, RGD:1581075, RGD:11041878, RGD:1581075 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon part_of IDA
IBA
ISS
ISO
IPI
PMID:21873635
GO_REF:0000024
(PMID:11323413), (PMID:15060152)
PMID:9139680
UniProt
RGD
PMID:11323413 PMID:15060152 PMID:9139680 PMID:9582312 PMID:9631509 More... GO_REF:0000024, RGD:1581073, RGD:1581075, RGD:11041878, RGD:13792537, RGD:1581073 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha part_of IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11323413)
UniProt
RGD
PMID:11323413 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    protein-containing complex 6133
      eukaryotic translation initiation factor 2B complex 6
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19686
      intracellular anatomical structure 14329
        cytoplasm 11357
          eukaryotic translation initiation factor 2B complex 6
paths to the root