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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 2 complex
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Accession:GO:0005850 term browser browse the term
Definition:Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
Synonyms:exact_synonym: eIF-2;   eIF2
 xref: Wikipedia:EIF-2


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eukaryotic translation initiation factor 2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2a eukaryotic translation initiation factor 2A part_of ISO (PMID:12133843) RGD PMID:12133843 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:3818593 RGD:1581069 NCBI chr12:37,444,136...37,452,391
Ensembl chr12:37,444,072...37,465,398
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha part_of IDA
ISO
IBA
(PMID:23063529)
PMID:21873635
RGD PMID:23063529, PMID:2450747, PMID:21873635 RGD:10395356, RGD:13792537 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta part_of ISO
IBA
(PMID:23063529)
PMID:21873635
RGD PMID:23063529, PMID:21873635 RGD:13792537 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma part_of ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:23063529)
UniProt
RGD
PMID:23063529, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:63,268,106...63,291,125
Ensembl chr  X:63,268,037...63,292,092
JBrowse link
G Eif2s3y eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked part_of IBA
ISS
PMID:21873635
GO_REF:0000024
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  Y:914,062...933,699
Ensembl chr  Y:914,045...933,699
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      eukaryotic translation initiation factor 2 complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11416
          eukaryotic translation initiation factor 2 complex 6
paths to the root