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ONTOLOGY REPORT - ANNOTATIONS

Term:eukaryotic translation initiation factor 2 complex
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Accession:GO:0005850 term browser browse the term
Definition:Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
Synonyms:exact_synonym: eIF-2;   eIF2
 xref: Wikipedia:EIF-2
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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eukaryotic translation initiation factor 2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2a eukaryotic translation initiation factor 2A part_of ISO (PMID:12133843) RGD PMID:12133843 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:3818593 RGD:1581069 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha part_of IDA
ISO
IBA		 UniProtKB:P41091 (PMID:23063529), (PMID:31836389)
GO_REF:0000033		 RGD
GO_Central		 PMID:23063529 PMID:31836389 PMID:2450747 GO_REF:0000033, RGD:10395356 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta part_of ISO
IBA		 UniProtKB:P05198 (PMID:23063529), (PMID:31836389)
GO_REF:0000033		 RGD
GO_Central		 PMID:23063529 PMID:31836389 GO_REF:0000033 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma part_of ISS
ISO
IBA		 GO_REF:0000024
PMID:31836389
UniProtKB:P05198 (PMID:23063529), (PMID:31836389)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:23063529 PMID:31836389 PMID:31836389 GO_REF:0000024 GO_REF:0000033, RGD:401901229 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686 		JBrowse link
G Eif2s3y eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr  Y:869,654...889,341
Ensembl chr  Y:869,689...889,340 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    protein-containing complex 6433
      eukaryotic translation initiation factor 2 complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      intracellular anatomical structure 15184
        cytoplasm 11877
          eukaryotic translation initiation factor 2 complex 6
paths to the root