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ONTOLOGY REPORT - ANNOTATIONS

Term:proteasome core complex
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Accession:GO:0005839 term browser browse the term
Definition:A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
Synonyms:exact_synonym: macropain
 narrow_synonym: 20S core complex;   20S proteasome;   PA28gamma-20S proteasome
 alt_id: GO:0000503


show annotations for term's descendants           Sort by:
proteasome core complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctrl chymotrypsin-like part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G ENSRNOG00000062555 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:224,032,844...224,034,987 JBrowse link
G ENSRNOG00000069501 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 7:96,706,207...96,707,107 JBrowse link
G ENSRNOG00000070269 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr  X:51,562,982...51,565,263 JBrowse link
G ENSRNOG00000070633 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr15:24,257,489...24,258,627 JBrowse link
G Psma1 proteasome 20S subunit alpha 1 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psma2 proteasome 20S subunit alpha 2 part_of ISO
ISS		 (PMID:34711951)
(MGI:5442509|PMID:16857966), (PMID:20498273)
GO_REF:0000024		 RGD
UniProt		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 part_of ISO
ISS		 (PMID:19208651), (PMID:34711951)
(MGI:5442509|PMID:16857966), (PMID:20498273)
GO_REF:0000024		 RGD
UniProt		 PMID:16857966 PMID:19208651 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:17540904), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:17540904 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731 		JBrowse link
G Psma6 proteasome 20S subunit alpha 6 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554 		JBrowse link
G Psma6-ps5 proteasome 20S subunit alpha 6, pseudogene 5 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:52,127,531...52,129,095 JBrowse link
G Psma7 proteasome 20S subunit alpha 7 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 part_of IEA
ISO
IBA
ISS		 GO_REF:0000107
(MGI:5442509|PMID:16857966), (PMID:17540904), (PMID:20498273)
GO_REF:0000033
GO_REF:0000002
(PMID:34711951)
GO_REF:0000024		 Ensembl
RGD
GO_Central
InterPro
UniProt		 PMID:16857966 PMID:17540904 PMID:20498273 PMID:34711951 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5442509 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 part_of ISS
ISO
IEA		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:17540904)
GO_REF:0000002		 UniProt
RGD
InterPro		 PMID:16857966 PMID:17540904 GO_REF:0000002 GO_REF:0000024 MGI:5442509 NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Psmb11 proteasome subunit beta 11 part_of ISO (PMID:17540904) RGD PMID:17540904 NCBI chr15:28,084,736...28,085,655 JBrowse link
G Psmb2 proteasome 20S subunit beta 2 part_of ISO
ISS		 (PMID:34711951)
(MGI:5442509|PMID:16857966), (PMID:17540904), (PMID:20498273)
GO_REF:0000024		 RGD
UniProt		 PMID:16857966 PMID:17540904 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137 		JBrowse link
G Psmb3 proteasome 20S subunit beta 3 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:10436176), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:10436176 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521 		JBrowse link
G Psmb4 proteasome 20S subunit beta 4 part_of ISS
ISO
IEA		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
GO_REF:0000107
(PMID:34711951)		 UniProt
RGD
Ensembl		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 GO_REF:0000107 MGI:5442509 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 part_of IEA
ISO
ISS		 GO_REF:0000107
(MGI:5442509|PMID:16857966), (PMID:15198663), (PMID:17540904), (PMID:20498273)
(PMID:34711951)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15198663 PMID:16857966 PMID:17540904 PMID:20498273 PMID:34711951 GO_REF:0000024 GO_REF:0000107 MGI:5442509 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Psmb6 proteasome 20S subunit beta 6 part_of ISS
ISO		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
(PMID:34711951)		 UniProt
RGD		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 MGI:5442509 NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586 		JBrowse link
G Psmb6l1 proteasome 20S subunit beta 6 like 1 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:93,833,914...93,834,630
Ensembl chr 2:93,833,830...93,834,635 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 part_of ISS
ISO
IEA		 GO_REF:0000024
(MGI:5442509|PMID:16857966), (PMID:20498273)
GO_REF:0000107
(PMID:34711951)		 UniProt
RGD
Ensembl		 PMID:16857966 PMID:20498273 PMID:34711951 GO_REF:0000024 GO_REF:0000107 MGI:5442509 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 part_of TAS
ISO
IEA
ISS		 (MGI:5442509|PMID:16857966), (PMID:17540904)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16857966 PMID:17540904 PMID:1451788 GO_REF:0000024 GO_REF:0000107 MGI:5442509, RGD:70234 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 part_of IEA
ISO		 GO_REF:0000002
(MGI:5442509|PMID:16857966), (PMID:17540904)		 InterPro
RGD		 PMID:16857966 PMID:17540904 GO_REF:0000002 MGI:5442509 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
proteasome core complex, alpha-subunit complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000066197 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:84,687,138...84,687,667 JBrowse link
G ENSRNOG00000066438 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 4:27,837,452...27,838,144 JBrowse link
G ENSRNOG00000069956 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr12:3,770,126...3,770,382 JBrowse link
G ENSRNOG00000070633 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr15:24,257,489...24,258,627 JBrowse link
G Psma1 proteasome 20S subunit alpha 1 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psma2 proteasome 20S subunit alpha 2 part_of ISS
IBA
IEA		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000104		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 part_of ISS
IBA
IEA		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000104		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 part_of ISO
IBA
ISS		 (PMID:30133132)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:30133132 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 part_of ISO
IBA
ISS
IEA		 (PMID:30133132)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:30133132 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731 		JBrowse link
G Psma6 proteasome 20S subunit alpha 6 part_of ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000104
(PMID:30133132), (PMID:9096325)		 BHF-UCL
GO_Central
UniProt
RGD		 PMID:9096325 PMID:30133132 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554 		JBrowse link
G Psma7 proteasome 20S subunit alpha 7 part_of ISO
IBA
IEA
ISS		 (PMID:30133132)
GO_REF:0000033
GO_REF:0000104
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:30133132 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672 		JBrowse link
G Psma8 proteasome 20S subunit alpha 8 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:5,863,594...5,928,226
Ensembl chr18:5,863,608...5,928,226 		JBrowse link
proteasome core complex, beta-subunit complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000070633 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr15:24,257,489...24,258,627 JBrowse link
G Psmb1 proteasome 20S subunit beta 1 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Psmb2 proteasome 20S subunit beta 2 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137 		JBrowse link
G Psmb3 proteasome 20S subunit beta 3 part_of ISS
IEA
IBA		 GO_REF:0000024
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521 		JBrowse link
G Psmb3l2 proteasome 20S subunit beta 3 like 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:118,672,316...118,672,933
Ensembl chr 3:118,672,233...118,672,933 		JBrowse link
G Psmb4 proteasome 20S subunit beta 4 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Psmb6 proteasome 20S subunit beta 6 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586 		JBrowse link
G Psmb6l1 proteasome 20S subunit beta 6 like 1 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:93,833,914...93,834,630
Ensembl chr 2:93,833,830...93,834,635 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      catalytic complex 1938
        proteasome core complex 30
          cytosolic proteasome core complex + 0
          nuclear proteasome core complex + 0
          proteasome core complex, alpha-subunit complex + 12
          proteasome core complex, beta-subunit complex + 13
Path 2
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      catalytic complex 1938
        peptidase complex 135
          endopeptidase complex 98
            proteasome complex 80
              proteasome core complex 30
                cytosolic proteasome core complex + 0
                nuclear proteasome core complex + 0
                proteasome core complex, alpha-subunit complex + 12
                proteasome core complex, beta-subunit complex + 13
paths to the root