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ONTOLOGY REPORT - ANNOTATIONS


Term:proteasome regulatory particle
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Accession:GO:0005838 term browser browse the term
Definition:A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.
Synonyms:exact_synonym: PA700-dependent proteasome activator
 narrow_synonym: 19S regulatory particle;   PA700 proteasome activator
 related_synonym: modulator complex


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proteasome regulatory particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psmc1 proteasome 26S subunit, ATPase 1 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273 MGI:MGI:4819897 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273 MGI:MGI:4819897 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 ISO
IEA
(MGI:MGI:4819897|PMID:20498273)
GO_REF:0000107
RGD
Ensembl
PMID:20498273 GO_REF:0000107, MGI:MGI:4819897 NCBI chr10:67,810,655...67,857,562
Ensembl chr10:67,810,655...67,857,223
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273, PMID:9426256 MGI:MGI:4819897, RGD:8693626 NCBI chr10:95,706,808...95,725,452
Ensembl chr10:95,706,685...95,725,812
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 ISO (MGI:MGI:1335627|PMID:10225435) RGD PMID:10225435 MGI:MGI:1335627 NCBI chr 1:213,636,159...213,648,499
Ensembl chr 1:213,636,093...213,648,488
JBrowse link
G Psmd2 proteasome 26S subunit, non-ATPase 2 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273 MGI:MGI:4819897 NCBI chr11:83,934,098...83,944,725
Ensembl chr11:83,934,087...83,944,763
JBrowse link
G Psmd3 proteasome 26S subunit, non-ATPase 3 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273 MGI:MGI:4819897 NCBI chr10:86,599,007...86,611,180
Ensembl chr10:86,599,220...86,611,188
JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:12,407,557...12,416,153
Ensembl chr15:12,407,524...12,416,105
JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 ISO (MGI:MGI:4819897|PMID:20498273) RGD PMID:20498273 MGI:MGI:4819897 NCBI chr19:39,639,432...39,646,718
Ensembl chr19:39,639,431...39,646,693
JBrowse link
proteasome regulatory particle, base subcomplex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psmc1 proteasome 26S subunit, ATPase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 9:93,080,618...93,155,033
Ensembl chr 9:93,080,615...93,155,027
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 colocalizes_with ISO
IEA
(PMID:19490896)
GO_REF:0000107
RGD
Ensembl
PMID:19490896 GO_REF:0000107 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Psmd2 proteasome 26S subunit, non-ATPase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:83,934,098...83,944,725
Ensembl chr11:83,934,087...83,944,763
JBrowse link
G Psmd4 proteasome 26S subunit, non-ATPase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:196,198,303...196,207,569
Ensembl chr 2:196,198,038...196,207,560
JBrowse link
G Psmd5 proteasome 26S subunit, non-ATPase 5 colocalizes_with ISO (PMID:19412159), (PMID:19490896) RGD PMID:19412159, PMID:19490896 NCBI chr 3:13,916,199...13,937,031
Ensembl chr 3:13,916,203...13,933,658
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 colocalizes_with ISO (PMID:19490896) RGD PMID:19490896 NCBI chr12:38,786,539...38,805,121
Ensembl chr12:38,786,540...38,805,121
JBrowse link
proteasome regulatory particle, lid subcomplex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrm1 adhesion regulating molecule 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,810,655...67,857,562
Ensembl chr10:67,810,655...67,857,223
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:95,706,808...95,725,452
Ensembl chr10:95,706,685...95,725,812
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,636,159...213,648,499
Ensembl chr 1:213,636,093...213,648,488
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 ISO
IBA
(PMID:22909820)
PMID:21873635
RGD PMID:22909820, PMID:21873635 RGD:13792537 NCBI chr 3:47,578,449...47,673,330
Ensembl chr 3:47,578,384...47,673,338
JBrowse link
G Psmd3 proteasome 26S subunit, non-ATPase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,599,007...86,611,180
Ensembl chr10:86,599,220...86,611,188
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:88,116,811...88,123,643
Ensembl chr 1:88,116,812...88,123,643
JBrowse link
G Sem1 SEM1, 26S proteasome complex subunit IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:32,067,444...32,087,600
Ensembl chr 4:32,067,444...32,087,600
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      proteasome regulatory particle 22
        cytosolic proteasome regulatory particle + 0
        nuclear proteasome regulatory particle + 0
        proteasome regulatory particle, base subcomplex + 12
        proteasome regulatory particle, lid subcomplex + 8
Path 2
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      catalytic complex 1487
        peptidase complex 103
          endopeptidase complex 79
            proteasome complex 73
              proteasome accessory complex 27
                proteasome regulatory particle 22
                  cytosolic proteasome regulatory particle + 0
                  nuclear proteasome regulatory particle + 0
                  proteasome regulatory particle, base subcomplex + 12
                  proteasome regulatory particle, lid subcomplex + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.