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ONTOLOGY REPORT - ANNOTATIONS


Term:TIM23 mitochondrial import inner membrane translocase complex
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Accession:GO:0005744 term browser browse the term
Definition:The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
Comment:See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
Synonyms:exact_synonym: mitochondrial inner membrane pre-sequence translocase complex;   mitochondrial inner membrane presequence translocase complex;   mitochondrial inner membrane translocase complex
 narrow_synonym: Tim23 complex


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TIM23 mitochondrial import inner membrane translocase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pam16 presequence translocase-asssociated motor 16 homolog (S. cerevisiae) JBrowse link 16 4,616,466 4,624,946 RGD:2290270
G Romo1 reactive oxygen species modulator 1 JBrowse link 2 156,144,153 156,145,794 RGD:2290270
G Timm17a translocase of inner mitochondrial membrane 17a JBrowse link 1 135,301,535 135,313,737 RGD:2290270
G Timm17b translocase of inner mitochondrial membrane 17b JBrowse link X 7,899,336 7,907,652 RGD:2290270
G Timm21 translocase of inner mitochondrial membrane 21 JBrowse link 18 84,946,191 84,951,530 RGD:2290270
G Timm23 translocase of inner mitochondrial membrane 23 JBrowse link 14 32,180,166 32,201,891 RGD:2290270
G Timm50 translocase of inner mitochondrial membrane 50 JBrowse link 7 28,305,516 28,312,046 RGD:2290270
PAM complex, Tim23 associated import motor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 14 77,826,217 77,874,917 RGD:2290270
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 JBrowse link 3 34,057,280 34,081,354 RGD:2290270
G Grpel1 GrpE-like 1, mitochondrial JBrowse link 5 36,465,185 36,474,077 RGD:2290270
G Grpel2 GrpE-like 2, mitochondrial JBrowse link 18 61,712,424 61,726,358 RGD:2290270
G Pam16 presequence translocase-asssociated motor 16 homolog (S. cerevisiae) JBrowse link 16 4,616,466 4,624,946 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23054
    protein-containing complex 5396
      membrane protein complex 1128
        inner mitochondrial membrane protein complex 128
          TIM23 mitochondrial import inner membrane translocase complex 11
            PAM complex, Tim23 associated import motor 5
Path 2
Term Annotations click to browse term
  cellular_component 23054
    cellular anatomical entity 18625
      organelle 12407
        membrane-bounded organelle 11156
          intracellular membrane-bounded organelle 10392
            mitochondrion 1835
              mitochondrial envelope 663
                mitochondrial membrane 617
                  mitochondrial inner membrane 441
                    inner mitochondrial membrane protein complex 128
                      TIM23 mitochondrial import inner membrane translocase complex 11
                        PAM complex, Tim23 associated import motor 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.