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ONTOLOGY REPORT - ANNOTATIONS


Term:TIM23 mitochondrial import inner membrane translocase complex
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Accession:GO:0005744 term browser browse the term
Definition:The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
Comment:See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
Synonyms:exact_synonym: mitochondrial inner membrane pre-sequence translocase complex;   mitochondrial inner membrane presequence translocase complex;   mitochondrial inner membrane translocase complex
 narrow_synonym: Tim23 complex


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TIM23 mitochondrial import inner membrane translocase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PAM16 presequence translocase associated motor 16 JBrowse link 16 4,340,251 4,351,321 RGD:2290271
G ROMO1 reactive oxygen species modulator 1 JBrowse link 20 35,699,310 35,700,982 RGD:2290271
G SLC25A6 solute carrier family 25 member 6 JBrowse link X
Y
1,386,152
1,386,152
1,392,113
1,392,113
RGD:2290271
G TIMM10 translocase of inner mitochondrial membrane 10 JBrowse link 11 57,528,464 57,542,505 RGD:2290271
G TIMM17A translocase of inner mitochondrial membrane 17A JBrowse link 1 201,955,503 201,970,664 RGD:2290271
G TIMM17B translocase of inner mitochondrial membrane 17B JBrowse link X 48,893,447 48,898,143 RGD:2290271
G TIMM21 translocase of inner mitochondrial membrane 21 JBrowse link 18 74,148,517 74,160,531 RGD:2290271
G TIMM23 translocase of inner mitochondrial membrane 23 JBrowse link 10 45,972,453 46,003,742 RGD:2290271
G TIMM23B translocase of inner mitochondrial membrane 23 homolog B JBrowse link 10 49,942,033 49,974,850 RGD:2290271
G TIMM50 translocase of inner mitochondrial membrane 50 JBrowse link 19 39,480,838 39,493,779 RGD:2290271
PAM complex, Tim23 associated import motor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJC15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 13 43,023,586 43,114,213 RGD:2290271
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 JBrowse link 3 180,983,709 180,989,774 RGD:2290271
G GRPEL1 GrpE like 1, mitochondrial JBrowse link 4 7,058,895 7,068,064 RGD:2290271
G GRPEL2 GrpE like 2, mitochondrial JBrowse link 5 149,345,499 149,354,583 RGD:2290271
G PAM16 presequence translocase associated motor 16 JBrowse link 16 4,340,251 4,351,321 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19009
    protein-containing complex 5615
      membrane protein complex 1320
        inner mitochondrial membrane protein complex 140
          TIM23 mitochondrial import inner membrane translocase complex 14
            PAM complex, Tim23 associated import motor 5
Path 2
Term Annotations click to browse term
  cellular_component 19009
    cellular anatomical entity 18812
      organelle 13891
        membrane-bounded organelle 12752
          intracellular membrane-bounded organelle 11049
            mitochondrion 1650
              mitochondrial envelope 775
                mitochondrial membrane 733
                  mitochondrial inner membrane 489
                    inner mitochondrial membrane protein complex 140
                      TIM23 mitochondrial import inner membrane translocase complex 14
                        PAM complex, Tim23 associated import motor 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.