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ONTOLOGY REPORT - ANNOTATIONS


Term:TIM23 mitochondrial import inner membrane translocase complex
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Accession:GO:0005744 term browser browse the term
Definition:The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
Comment:See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
Synonyms:exact_synonym: mitochondrial inner membrane pre-sequence translocase complex;   mitochondrial inner membrane presequence translocase complex;   mitochondrial inner membrane translocase complex
 narrow_synonym: Tim23 complex


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TIM23 mitochondrial import inner membrane translocase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100362432 mitochondrial import inner membrane translocase subunit Tim23-like JBrowse link 3 82,970,785 82,971,887 RGD:13792537
G LOC100910944 reactive oxygen species modulator 1-like JBrowse link 3 152,222,703 152,224,314 RGD:13792537
G LOC100911130 mitochondrial import inner membrane translocase subunit Tim17-B-like JBrowse link X 15,340,557 15,347,682 RGD:13792537
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 JBrowse link 10 91,752,860 91,753,380 RGD:13792537
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:13792537
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:13792537
G Timm17a translocase of inner mitochondrial membrane 17A JBrowse link 13 52,124,641 52,136,127 RGD:1624291
RGD:13792537
G Timm17b translocase of inner mitochondrial membrane 17b JBrowse link X 15,441,369 15,448,452 RGD:1624291
RGD:13792537
G Timm21 translocase of inner mitochondrial membrane 21 JBrowse link 18 81,803,165 81,807,627 RGD:1624291
RGD:13792537
RGD:1600115
G Timm23 translocase of inner mitochondrial membrane 23 JBrowse link 16 8,324,038 8,350,067 RGD:1624291
RGD:13792537
G Timm50 translocase of inner mitochondrial membrane 50 JBrowse link 1 85,470,810 85,480,813 RGD:1624291
RGD:13792537
PAM complex, Tim23 associated import motor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 15 59,990,131 60,056,710 RGD:13792537
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 JBrowse link 2 120,503,093 120,531,782 RGD:13792537
G Grpel1 GrpE-like 1, mitochondrial JBrowse link 14 79,458,951 79,464,782 RGD:13792537
G Grpel2 GrpE-like 2, mitochondrial JBrowse link 18 57,037,995 57,050,234 RGD:13792537
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19738
    protein-containing complex 5748
      membrane protein complex 1201
        inner mitochondrial membrane protein complex 150
          TIM23 mitochondrial import inner membrane translocase complex 15
            PAM complex, Tim23 associated import motor 5
Path 2
Term Annotations click to browse term
  cellular_component 19738
    cellular anatomical entity 19354
      organelle 12457
        membrane-bounded organelle 10811
          intracellular membrane-bounded organelle 9924
            mitochondrion 1610
              mitochondrial envelope 650
                mitochondrial membrane 597
                  mitochondrial inner membrane 374
                    inner mitochondrial membrane protein complex 150
                      TIM23 mitochondrial import inner membrane translocase complex 15
                        PAM complex, Tim23 associated import motor 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.