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ONTOLOGY REPORT - ANNOTATIONS

Term:U2-type spliceosomal complex
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Accession:GO:0005684 term browser browse the term
Definition:Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
Comment:A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.
Synonyms:exact_synonym: major (U2-type) spliceosomal complex;   major spliceosomal complex
 narrow_synonym: GT-AG spliceosome


show annotations for term's descendants           Sort by:
U2-type spliceosomal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bud13 BUD13 homolog part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:46,575,124...46,590,964
Ensembl chr 8:46,575,115...46,590,958 		JBrowse link
G Ccdc12 coiled-coil domain containing 12 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417 		JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354 		JBrowse link
G Ddx46 DEAD-box helicase 46 part_of ISS
ISO		 GO_REF:0000024
(PMID:32494006), (PMID:34822310), (PMID:36797247)		 UniProt
RGD		 PMID:32494006 PMID:34822310 PMID:36797247 GO_REF:0000024 NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 part_of ISO
IBA		 (PMID:32494006), (PMID:34822310), (PMID:36797247)
GO_REF:0000033		 RGD
GO_Central		 PMID:32494006 PMID:34822310 PMID:36797247 GO_REF:0000033 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607 		JBrowse link
G Phf5a PHD finger protein 5A part_of ISO (PMID:27720643), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:27720643 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460 		JBrowse link
G Rnf113a1 ring finger protein 113A1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:116,427,941...116,429,164
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Sf3a1 splicing factor 3A subunit 1 part_of ISO (PMID:10882114), (PMID:32494006), (PMID:36797247) RGD PMID:10882114 PMID:32494006 PMID:36797247 NCBI chr14:79,031,394...79,052,144
Ensembl chr14:79,031,394...79,052,144 		JBrowse link
G Sf3a2 splicing factor 3A subunit 2 part_of ISO (PMID:10882114), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:10882114 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr 7:8,909,507...8,916,104
Ensembl chr 7:8,909,507...8,915,530 		JBrowse link
G Sf3a3 splicing factor 3a, subunit 3 part_of ISO (PMID:10882114), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:10882114 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 part_of ISO (PMID:27720643), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:27720643 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 part_of IBA
ISO		 GO_REF:0000033
(PMID:27720643), (PMID:32494006), (PMID:34822310), (PMID:36797247)		 GO_Central
RGD		 PMID:27720643 PMID:32494006 PMID:34822310 PMID:36797247 GO_REF:0000033 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 part_of ISO (PMID:27720643), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:27720643 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 part_of ISS
ISO		 GO_REF:0000024
(PMID:27720643), (PMID:32494006), (PMID:36797247)		 UniProt
RGD		 PMID:27720643 PMID:32494006 PMID:36797247 GO_REF:0000024 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sf3b5 splicing factor 3b, subunit 5 part_of ISO (PMID:27720643), (PMID:32494006), (PMID:34822310), (PMID:36797247) RGD PMID:27720643 PMID:32494006 PMID:34822310 PMID:36797247 NCBI chr 1:7,357,040...7,357,752
Ensembl chr 1:7,350,731...7,357,839 		JBrowse link
G Sf3b6 splicing factor 3B, subunit 6 part_of IBA
ISO		 GO_REF:0000033
(PMID:27720643), (PMID:32494006), (PMID:34822310)		 GO_Central
RGD		 PMID:27720643 PMID:32494006 PMID:34822310 GO_REF:0000033 NCBI chr 6:27,826,044...27,835,086
Ensembl chr 6:27,826,029...27,835,156 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO (PMID:32494006), (PMID:36797247) RGD PMID:32494006 PMID:36797247 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Yju2b YJU2 splicing factor homolog B part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:23,894,587...23,906,084
Ensembl chr19:23,894,649...23,906,077 		JBrowse link
commitment complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000066758 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr  X:14,995,412...14,996,454 JBrowse link
G LOC120099250 U1 small nuclear ribonucleoprotein C-like part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr  X:135,673,708...135,678,865 JBrowse link
G Prpf39 pre-mRNA processing factor 39 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:83,088,981...83,113,826
Ensembl chr 6:83,088,986...83,113,825 		JBrowse link
G Snrpc small nuclear ribonucleoprotein polypeptide C part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr20:5,888,453...5,906,638
Ensembl chr20:5,888,453...5,906,638 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:68,760,911...68,779,730
Ensembl chr 1:68,760,924...68,778,492 		JBrowse link
U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casc3 CASC3 exon junction complex subunit part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29301961)		 UniProt
Ensembl
RGD		 PMID:29301961 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228 		JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 part_of ISO
ISS		 (PMID:29301961)
GO_REF:0000024		 RGD
UniProt		 PMID:29301961 GO_REF:0000024 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Isy1 ISY1 splicing factor homolog part_of ISS
ISO		 GO_REF:0000024
(PMID:29301961)		 UniProt
RGD		 PMID:29301961 GO_REF:0000024 NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188 		JBrowse link
G LOC134482366 splicing factor YJU2-like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Magohb mago homolog B, exon junction complex subunit part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 4:165,034,131...165,041,977
Ensembl chr 4:165,034,122...165,041,967 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Rbm22 RNA binding motif protein 22 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569 		JBrowse link
G Rbm8a RNA binding motif protein 8A part_of ISS
ISO		 GO_REF:0000024
(PMID:29301961)		 UniProt
RGD		 PMID:29301961 GO_REF:0000024 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29301961)		 UniProt
Ensembl
RGD		 PMID:29301961 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Yju2 YJU2 splicing factor part_of ISO
IBA		 (PMID:29301961)
GO_REF:0000033		 RGD
GO_Central		 PMID:29301961 GO_REF:0000033 NCBI chr 9:789,603...799,505
Ensembl chr 9:789,606...799,496 		JBrowse link
U2-type catalytic step 2 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqr aquarius intron-binding spliceosomal factor part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044 		JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Bud31 BUD31 homolog part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509 		JBrowse link
G Cdc40 cell division cycle 40 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358 		JBrowse link
G Cdc5l cell division cycle 5-like part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28076346 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Crnkl1 crooked neck pre-mRNA splicing factor 1 part_of ISS
ISO
IBA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:28076346 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302
Ensembl chr 6:133,337,039...133,354,302 		JBrowse link
G Cwc15 CWC15 spliceosome-associated protein part_of ISO
ISS		 (PMID:28076346)
GO_REF:0000024		 RGD
UniProt		 PMID:28076346 GO_REF:0000024 NCBI chr 8:11,305,401...11,316,326
Ensembl chr 8:11,305,424...11,316,325 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228 		JBrowse link
G Dhx8 DEAH-box helicase 8 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 part_of ISO
IBA		 (PMID:28076346)
GO_REF:0000033		 RGD
GO_Central		 PMID:28076346 GO_REF:0000033 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079 		JBrowse link
G Plrg1 pleiotropic regulator 1 part_of ISO
ISS
IEA		 (PMID:28076346)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28076346 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522 		JBrowse link
G Ppie peptidylprolyl isomerase E part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 5:135,406,172...135,419,332
Ensembl chr 5:135,406,176...135,419,235 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of ISO
IEA		 (PMID:28076346)
GO_REF:0000107		 RGD
Ensembl		 PMID:28076346 GO_REF:0000107 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Rbm22 RNA binding motif protein 22 part_of ISO
IBA		 (PMID:28076346)
GO_REF:0000033		 RGD
GO_Central		 PMID:28076346 GO_REF:0000033 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein U5 subunit 40 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 5:142,700,632...142,733,776
Ensembl chr 5:142,700,534...142,733,776 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISO
ISS		 (PMID:28076346)
GO_REF:0000024		 RGD
UniProt		 PMID:28076346 GO_REF:0000024 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Snw1 SNW domain containing 1 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor part_of ISS
ISO		 GO_REF:0000024
(PMID:28076346)		 UniProt
RGD		 PMID:28076346 GO_REF:0000024 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414 		JBrowse link
G Xab2 XPA binding protein 2 part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:28076346 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:1,667,672...1,679,702
Ensembl chr12:1,667,672...1,679,692 		JBrowse link
U2-type post-mRNA release spliceosomal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx15 DEAH-box helicase 15 located_in ISO (PMID:19103666) RGD PMID:19103666 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088 		JBrowse link
G Gcfc2 GC-rich sequence DNA-binding factor 2 part_of ISO (PMID:24304693) RGD PMID:24304693 NCBI chr 4:114,481,613...114,519,268
Ensembl chr 4:114,481,607...114,519,962 		JBrowse link
G Tfip11 tuftelin interacting protein 11 part_of ISO
IBA
ISS		 (PMID:19103666)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19103666 GO_REF:0000024 GO_REF:0000033 NCBI chr12:44,299,619...44,311,851
Ensembl chr12:44,299,622...44,311,855 		JBrowse link
U2-type post-spliceosomal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prpf18 pre-mRNA processing factor 18 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:73,630,560...73,661,210
Ensembl chr17:73,630,571...73,690,979 		JBrowse link
U2-type precatalytic spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bud13 BUD13 homolog part_of IEA
ISO
ISS		 GO_REF:0000107
(PMID:29360106)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29360106 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:46,575,124...46,590,964
Ensembl chr 8:46,575,115...46,590,958 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein part_of ISO (PMID:29360106) RGD PMID:29360106 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228 		JBrowse link
G Cwc27 CWC27 spliceosome associated cyclophilin part_of ISO
IEA
ISS		 (PMID:29360106)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29360106 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872 		JBrowse link
G Dhx16 DEAH-box helicase 16 part_of ISO (PMID:29360106) RGD PMID:29360106 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 part_of ISO (PMID:29361316) RGD PMID:29361316 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079 		JBrowse link
G Ik IK cytokine part_of ISS
ISO		 GO_REF:0000024
(PMID:28781166)		 UniProt
RGD		 PMID:28781166 GO_REF:0000024 NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832 		JBrowse link
G Linc00176 long intergenic non-protein coding RNA 176 part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:168,771,350...168,775,133
Ensembl chr 3:168,704,299...168,774,991 		JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266 		JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269 		JBrowse link
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr16:18,755,481...18,761,106
Ensembl chr16:18,755,484...18,760,926 		JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165 		JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
G Lsm8 LSM8 homolog, U6 small nuclear RNA associated part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 4:47,306,259...47,312,125
Ensembl chr 4:47,306,295...47,314,293 		JBrowse link
G Magohb mago homolog B, exon junction complex subunit part_of ISO (PMID:28502770) RGD PMID:28502770 NCBI chr 4:165,034,131...165,041,977
Ensembl chr 4:165,034,122...165,041,967 		JBrowse link
G Mfap1a microfibrillar-associated protein 1A part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 3:108,440,163...108,456,744
Ensembl chr 3:108,438,845...108,456,750 		JBrowse link
G Phf5a PHD finger protein 5A part_of ISO (PMID:29360106) RGD PMID:29360106 NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460 		JBrowse link
G Prpf3 pre-mRNA processing factor 3 part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 2:183,379,041...183,403,526
Ensembl chr 2:183,378,718...183,403,489 		JBrowse link
G Prpf31 pre-mRNA processing factor 31 part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 1:65,575,887...65,587,561
Ensembl chr 1:65,575,887...65,587,873 		JBrowse link
G Prpf38a pre-mRNA processing factor 38A part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 5:123,312,461...123,324,160
Ensembl chr 5:123,311,482...123,323,972 		JBrowse link
G Prpf4 pre-mRNA splicing tri-snRNP complex factor 4 part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 5:75,859,934...75,873,924
Ensembl chr 5:75,859,924...75,873,919 		JBrowse link
G Prpf6 pre-mRNA processing factor 6 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28781166)		 UniProt
Ensembl
RGD		 PMID:28781166 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:28781166), (PMID:29361316), (PMID:30315277) RGD PMID:28781166 PMID:29361316 PMID:30315277 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Rbmx2 RNA binding motif protein, X-linked 2 part_of ISO
ISS		 (PMID:29360106)
GO_REF:0000024		 RGD
UniProt		 PMID:29360106 GO_REF:0000024 NCBI chr  X:127,888,514...127,896,239
Ensembl chr  X:127,888,438...127,896,869 		JBrowse link
G Rnf113a1 ring finger protein 113A1 part_of ISO (PMID:29360106) RGD PMID:29360106 NCBI chr  X:116,427,941...116,429,164
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136 		JBrowse link
G Sf3a1 splicing factor 3A subunit 1 part_of ISO (PMID:10882114), (PMID:29360106) RGD PMID:10882114 PMID:29360106 NCBI chr14:79,031,394...79,052,144
Ensembl chr14:79,031,394...79,052,144 		JBrowse link
G Sf3a2 splicing factor 3A subunit 2 part_of ISS
ISO		 GO_REF:0000024
(PMID:29360106)		 UniProt
RGD		 PMID:29360106 GO_REF:0000024 NCBI chr 7:8,909,507...8,916,104
Ensembl chr 7:8,909,507...8,915,530 		JBrowse link
G Sf3a3 splicing factor 3a, subunit 3 part_of ISO (PMID:29360106), (PMID:8022796) RGD PMID:8022796 PMID:29360106 NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 part_of ISO (PMID:28781166), (PMID:29360106) RGD PMID:28781166 PMID:29360106 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 part_of ISO (PMID:29360106) RGD PMID:29360106 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 part_of ISO (PMID:28781166), (PMID:29360106) RGD PMID:28781166 PMID:29360106 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 part_of ISO
IEA		 (PMID:29360106)
GO_REF:0000107		 RGD
Ensembl		 PMID:29360106 GO_REF:0000107 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sf3b5 splicing factor 3b, subunit 5 part_of ISO (PMID:28781166), (PMID:29360106) RGD PMID:28781166 PMID:29360106 NCBI chr 1:7,357,040...7,357,752
Ensembl chr 1:7,350,731...7,357,839 		JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor part_of IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:28781166)		 Ensembl
UniProt
RGD		 PMID:28781166 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:55,856,691...55,875,262
Ensembl chr 5:55,856,246...55,875,300 		JBrowse link
G Snip1 Smad nuclear interacting protein 1 part_of ISS
ISO		 GO_REF:0000024
(PMID:29360106)		 UniProt
RGD		 PMID:29360106 GO_REF:0000024 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29361316)		 UniProt
Ensembl
RGD		 PMID:29361316 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISS
ISO		 GO_REF:0000024
(PMID:28781166)		 UniProt
RGD		 PMID:28781166 GO_REF:0000024 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 part_of ISO
ISS		 (PMID:28781166)
GO_REF:0000024		 RGD
UniProt		 PMID:28781166 GO_REF:0000024 NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 part_of ISO (PMID:29361316) RGD PMID:29361316 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751 		JBrowse link
G Txnl4a thioredoxin-like 4A part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr18:73,659,107...73,674,893
Ensembl chr18:73,659,107...73,674,893 		JBrowse link
G Wbp4 WW domain binding protein 4 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28781166)		 UniProt
Ensembl
RGD		 PMID:28781166 GO_REF:0000024 GO_REF:0000107 NCBI chr15:54,862,700...54,890,668
Ensembl chr15:54,862,843...54,890,647 		JBrowse link
G Zmat2 zinc finger, matrin type 2 part_of ISO (PMID:28781166) RGD PMID:28781166 NCBI chr18:28,409,606...28,414,241
Ensembl chr18:28,398,795...28,414,747 		JBrowse link
U2-type prespliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07042226.1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr  X:144,806,986...144,812,552 JBrowse link
G Ddx42 DEAD-box helicase 42 part_of ISO (PMID:36797247) RGD PMID:36797247 NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939 		JBrowse link
G ENSRNOG00000066758 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr  X:14,995,412...14,996,454 JBrowse link
G LOC120099250 U1 small nuclear ribonucleoprotein C-like part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr  X:135,673,708...135,678,865 JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
G Luc7l LUC7-like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112 		JBrowse link
G Luc7l2 LUC7-like 2 pre-mRNA splicing factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,287,593...67,347,986
Ensembl chr 4:67,287,640...67,347,964 		JBrowse link
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538 		JBrowse link
G Luc7l3-ps2 LUC7-like 3 pre-mRNA splicing factor, pseudogene 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:49,653,487...49,655,419 JBrowse link
G Prpf39 pre-mRNA processing factor 39 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:83,088,981...83,113,826
Ensembl chr 6:83,088,986...83,113,825 		JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886 		JBrowse link
G Prpf40b pre-mRNA processing factor 40 homolog B part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:130,392,611...130,454,053
Ensembl chr 7:130,432,112...130,454,052 		JBrowse link
G Sf3a1 splicing factor 3A subunit 1 part_of ISO
IBA		 (PMID:10882114)
GO_REF:0000033		 RGD
GO_Central		 PMID:10882114 GO_REF:0000033 NCBI chr14:79,031,394...79,052,144
Ensembl chr14:79,031,394...79,052,144 		JBrowse link
G Sf3a2 splicing factor 3A subunit 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,909,507...8,916,104
Ensembl chr 7:8,909,507...8,915,530 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:95,856,038...95,876,434
Ensembl chr 1:95,856,036...95,876,392 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpc small nuclear ribonucleoprotein polypeptide C part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr20:5,888,453...5,906,638
Ensembl chr20:5,888,453...5,906,638 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Snrpgl1 small nuclear ribonucleoprotein polypeptide G like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:87,982,629...87,983,056
Ensembl chr 1:87,982,626...87,983,118
Ensembl chr 4:87,982,626...87,983,118 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634 		JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 part_of ISO
IBA		 (PMID:2531895)
GO_REF:0000033		 RGD
GO_Central		 PMID:2531895 GO_REF:0000033 NCBI chr 1:68,760,911...68,779,730
Ensembl chr 1:68,760,924...68,778,492 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20817
    protein-containing complex 6437
      nuclear protein-containing complex 1305
        spliceosomal complex 222
          U2-type spliceosomal complex 100
            U2-type catalytic step 1 spliceosome 13
            U2-type catalytic step 2 spliceosome 30
            U2-type post-mRNA release spliceosomal complex 3
            U2-type post-spliceosomal complex 1
            U2-type precatalytic spliceosome 51
            U2-type prespliceosome 22
            commitment complex 7
Path 2
Term Annotations click to browse term
  cellular_component 20817
    cellular anatomical entity 20577
      organelle 14007
        membrane-bounded organelle 12604
          intracellular membrane-bounded organelle 12056
            nucleus 7484
              nuclear protein-containing complex 1305
                spliceosomal complex 222
                  U2-type spliceosomal complex 100
                    U2-type catalytic step 1 spliceosome 13
                    U2-type catalytic step 2 spliceosome 30
                    U2-type post-mRNA release spliceosomal complex 3
                    U2-type post-spliceosomal complex 1
                    U2-type precatalytic spliceosome 51
                    U2-type prespliceosome 22
                    commitment complex 7
paths to the root