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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription factor TFIIH holo complex
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Accession:GO:0005675 term browser browse the term
Definition:A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.
Synonyms:exact_synonym: holo TFIIH complex



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transcription factor TFIIH holo complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063323.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:27,111,331...27,111,546 JBrowse link
G Ccnh cyclin H part_of ISS
ISO
GO_REF:0000024
(PMID:9852112)
UniProt
RGD
PMID:9852112 GO_REF:0000024 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IDA
ISO
ISS
(PMID:9852112)
GO_REF:0000024
RGD
UniProt
PMID:9852112 PMID:7553866 GO_REF:0000024, RGD:9590319 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit part_of ISO (PMID:9852112) RGD PMID:9852112 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit part_of IBA
ISO
ISS
PMID:21873635
(PMID:9852112)
GO_REF:0000024
RGD
UniProt
PMID:9852112 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7553866 RGD:9590319 NCBI chr15:51,206,027...51,327,166
Ensembl chr15:51,206,031...51,327,253
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 part_of IDA
ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:7553866 PMID:21873635 RGD:9590319, RGD:13792537 NCBI chr 1:97,321,401...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 part_of IBA
ISS
PMID:21873635
GO_REF:0000024
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
ISS
IBA
(PMID:9852112)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:9852112 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:21873635 RGD:13792537 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:21873635 RGD:13792537 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link
core TFIIH complex portion of holo TFIIH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2h2 general transcription factor IIH subunit 2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
ISS
(PMID:27193682)
GO_REF:0000024
RGD
UniProt
PMID:27193682 GO_REF:0000024 NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
JBrowse link
transcription factor TFIIK complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H part_of IBA
ISO
PMID:21873635
(PMID:8692841)
RGD PMID:8692841 PMID:21873635 RGD:13792537 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:8692841)
Ensembl
RGD
PMID:8692841 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO (PMID:8692841) RGD PMID:8692841 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    protein-containing complex 6165
      nuclear protein-containing complex 1289
        RNA polymerase II transcription regulator complex 234
          transcription factor TFIIH holo complex 12
            core TFIIH complex portion of holo TFIIH complex 3
            transcription factor TFIIK complex 3
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      organelle 13088
        membrane-bounded organelle 11697
          intracellular membrane-bounded organelle 11218
            nucleus 7051
              nuclear lumen 3941
                nucleoplasm 3473
                  RNA polymerase II, holoenzyme 79
                    transcription factor TFIIH holo complex 12
                      core TFIIH complex portion of holo TFIIH complex 3
                      transcription factor TFIIK complex 3
paths to the root