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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription factor TFIID complex
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Accession:GO:0005669 term browser browse the term
Definition:A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.


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transcription factor TFIID complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063323.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:28,557,633...28,557,848 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO (PMID:27193682) RGD PMID:27193682 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit ISO (PMID:27193682) RGD PMID:27193682 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr 6:115,321,110...115,352,659
Ensembl chr 6:115,320,467...115,352,681
JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr 8:76,422,341...76,435,587
Ensembl chr 8:76,422,359...76,435,473
JBrowse link
G Gtf2b general transcription factor IIB IEA
ISO
GO_REF:0000107
(PMID:27193682)
Ensembl
RGD
PMID:27193682 GO_REF:0000107 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr11:66,078,786...66,111,394
Ensembl chr11:66,078,820...66,110,848
JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr16:62,113,846...62,164,339
Ensembl chr16:62,113,854...62,164,135
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr12:37,427,556...37,444,027
Ensembl chr12:37,427,546...37,444,282
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 ISO
IBA
(PMID:27193682)
PMID:21873635
RGD PMID:27193682, PMID:21873635 RGD:13792537 NCBI chr 1:46,978,345...46,985,032
Ensembl chr 1:46,978,458...46,985,032
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 ISO (PMID:14580349), (PMID:24927529), (PMID:25412659), (PMID:27007846), (PMID:29111974), (PMID:8625415) RGD PMID:8625415, PMID:14580349, PMID:24927529, PMID:25412659, PMID:27007846, PMID:29111974 NCBI chr  X:71,412,291...71,486,456
Ensembl chr  X:71,412,289...71,485,085
JBrowse link
G Taf10 TATA-box binding protein associated factor 10 ISO (PMID:14580349), (PMID:15099517), (PMID:29111974), (PMID:7729427), (PMID:7923369) RGD PMID:7729427, PMID:7923369, PMID:14580349, PMID:15099517, PMID:29111974 NCBI chr 1:170,585,160...170,586,428
Ensembl chr 1:170,585,167...170,586,603
JBrowse link
G Taf11 TATA-box binding protein associated factor 11 IBA
ISO
PMID:21873635
(PMID:14580349), (PMID:29111974), (PMID:7729427), (PMID:8670810)
RGD PMID:7729427, PMID:8670810, PMID:14580349, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr20:7,476,648...7,484,417
Ensembl chr20:7,476,651...7,482,747
JBrowse link
G Taf12 TATA-box binding protein associated factor 12 IBA
ISO
PMID:21873635
(PMID:14580349), (PMID:29111974)
RGD PMID:14580349, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 5:150,459,701...150,476,521
Ensembl chr 5:150,459,713...150,475,186
JBrowse link
G Taf13 TATA-box binding protein associated factor 13 ISO
IBA
(PMID:29111974), (PMID:7729427)
PMID:21873635
RGD PMID:7729427, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 2:211,359,623...211,370,285
Ensembl chr 2:211,359,623...211,370,284
JBrowse link
G Taf2 TATA-box binding protein associated factor 2 IBA
ISO
PMID:21873635
(PMID:10409744), (PMID:14580349), (PMID:27007846), (PMID:29111974), (PMID:9774672)
RGD PMID:9774672, PMID:10409744, PMID:14580349, PMID:27007846, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 7:94,698,987...94,755,924
Ensembl chr 7:94,698,987...94,755,924
JBrowse link
G Taf3 TATA-box binding protein associated factor 3 ISO (PMID:11438666), (PMID:29111974) RGD PMID:11438666, PMID:29111974 NCBI chr17:72,240,785...72,393,448
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Taf4 TATA-box binding protein associated factor 4 ISO
IBA
(PMID:14580349), (PMID:29111974)
PMID:21873635
RGD PMID:14580349, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 3:175,300,842...175,364,655
Ensembl chr 3:175,301,879...175,327,689
JBrowse link
G Taf4b TATA-box binding protein associated factor 4b ISO
IBA
(PMID:29111974)
PMID:21873635
RGD PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr18:6,206,939...6,338,794
Ensembl chr18:6,207,280...6,318,219
JBrowse link
G Taf5 TATA-box binding protein associated factor 5 IBA
ISO
PMID:21873635
(PMID:14580349), (PMID:29111974), (PMID:9045704)
RGD PMID:9045704, PMID:14580349, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 1:266,844,480...266,859,965
Ensembl chr 1:266,844,480...266,859,965
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:14580349), (PMID:27007846), (PMID:29111974), (PMID:8262073)
Ensembl
RGD
PMID:8262073, PMID:14580349, PMID:27007846, PMID:29111974, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637
JBrowse link
G Taf6l TATA-box binding protein associated factor 6 like IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:224,974,238...224,986,819
Ensembl chr 1:224,974,208...224,986,291
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 ISO
IBA
(MGI:MGI:1342782|PMID:10438527)
(PMID:14580349), (PMID:24927529), (PMID:25412659), (PMID:27007846), (PMID:29111974), (PMID:7824954)
PMID:21873635
RGD PMID:7824954, PMID:10438527, PMID:14580349, PMID:24927529, PMID:25412659, PMID:27007846, PMID:29111974, PMID:21873635 MGI:MGI:1342782, RGD:13792537 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
G Taf7l TATA-box binding protein associated factor 7-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:105,292,338...105,308,554
Ensembl chr  X:105,292,338...105,308,554
JBrowse link
G Taf7l-ps1 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, pseudogene 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:59,138,768...59,139,910 JBrowse link
G Taf7l2 Taf7l2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:59,138,768...59,139,910 JBrowse link
G Taf8 TATA-box binding protein associated factor 8 ISO
IBA
(PMID:14580349), (PMID:27007846), (PMID:29111974)
PMID:21873635
RGD PMID:14580349, PMID:27007846, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 9:15,513,048...15,532,992
Ensembl chr 9:15,513,063...15,529,800
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 IBA
ISO
PMID:21873635
(PMID:14580349), (PMID:15899866), (PMID:29111974)
RGD PMID:14580349, PMID:15899866, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr 2:30,664,407...30,668,414
Ensembl chr 2:30,664,639...30,668,414
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b IBA
ISO
PMID:21873635
(PMID:15899866), (PMID:29111974)
RGD PMID:15899866, PMID:29111974, PMID:21873635 RGD:13792537 NCBI chr  X:77,281,234...77,295,238
Ensembl chr  X:77,281,210...77,295,426
JBrowse link
G Tbp TATA box binding protein IDA
ISO
(PMID:14580349), (PMID:27007846), (PMID:27193682), (PMID:29111974), (PMID:7729427) RGD PMID:7729427, PMID:14580349, PMID:27007846, PMID:27193682, PMID:29111974, PMID:7980586 RGD:2306552 NCBI chr 1:57,491,381...57,509,335
Ensembl chr 1:57,491,643...57,508,449
JBrowse link
G Tcea1 transcription elongation factor A1 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tp53 tumor protein p53 colocalizes_with ISO (PMID:15053879) RGD PMID:15053879 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      transcription regulator complex 434
        RNA polymerase II transcription regulator complex 162
          transcription factor TFIID complex 34
            TAF4B-containing transcription factor TFIID complex 0
Path 2
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      catalytic complex 1487
        transferase complex 818
          transferase complex, transferring phosphorus-containing groups 266
            RNA polymerase complex 110
              DNA-directed RNA polymerase complex 108
                nuclear DNA-directed RNA polymerase complex 107
                  RNA polymerase II, holoenzyme 84
                    transcription factor TFIID complex 34
                      TAF4B-containing transcription factor TFIID complex 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.