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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA polymerase III complex
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Accession:GO:0005666 term browser browse the term
Definition:RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Synonyms:exact_synonym: DNA-directed RNA polymerase III complex
 related_synonym: DNA-directed RNA polymerase III activity


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RNA polymerase III complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASL argininosuccinate lyase part_of IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:59,908,648...59,948,822
Ensembl chr 7:73,142,842...73,157,472
Ensembl chr 7:73,142,842...73,157,472
Ensembl chr 7:73,142,842...73,157,472 		JBrowse link
G CRCP CGRP receptor component part_of IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
G LOC103786072 DNA-directed RNA polymerases I and III subunit RPAC2 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:8,910,717...8,913,420
Ensembl chr13:27,256,567...27,373,830 		JBrowse link
G POLR1C RNA polymerase I and III subunit C part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:43,101,771...43,121,460
Ensembl chr 6:44,395,787...44,412,257 		JBrowse link
G POLR1D RNA polymerase I and III subunit D part_of ISO (PMID:33335104), (PMID:34675218) UniProt PMID:33335104 PMID:34675218 NCBI chr13:8,911,839...8,957,363
Ensembl chr13:27,256,567...27,373,830 		JBrowse link
G POLR2E RNA polymerase II, I and III subunit E part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:32,263...41,992
Ensembl chr19:1,065,421...1,073,379 		JBrowse link
G POLR2F RNA polymerase II, I and III subunit F part_of IEA TreeGrafter GO_REF:0000118 NCBI chr22:18,868,872...18,988,918
Ensembl chr22:36,796,015...36,814,469 		JBrowse link
G POLR2H RNA polymerase II, I and III subunit H part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:181,399,136...181,405,680
Ensembl chr 3:189,881,594...189,887,608 		JBrowse link
G POLR2K RNA polymerase II, I and III subunit K part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:96,791,485...96,794,913
Ensembl chr 8:98,965,837...98,969,221 		JBrowse link
G POLR2L RNA polymerase II, I and III subunit L part_of ISO (PMID:33335104), (PMID:34675218) UniProt PMID:33335104 PMID:34675218 NCBI chr11:859,015...861,382 JBrowse link
G POLR3A RNA polymerase III subunit A part_of ISO (PMID:24107381), (PMID:33335104), (PMID:34675218) UniProt PMID:24107381 PMID:33335104 PMID:34675218 NCBI chr10:74,496,121...74,550,054 JBrowse link
G POLR3B RNA polymerase III subunit B part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:103,936,650...104,083,470
Ensembl chr12:107,330,306...107,477,279 		JBrowse link
G POLR3C RNA polymerase III subunit C part_of IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:121,917,371...121,935,976
Ensembl chr 1:113,733,846...113,752,486 		JBrowse link
G POLR3D RNA polymerase III subunit D part_of IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:21,489,492...21,499,948
Ensembl chr 8:18,429,013...18,435,060 		JBrowse link
G POLR3E RNA polymerase III subunit E part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:16,397,988...16,434,949
Ensembl chr16:22,609,181...22,645,511 		JBrowse link
G POLR3F RNA polymerase III subunit F part_of IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr20:18,429,402...18,447,634
Ensembl chr20:18,400,976...18,418,225 		JBrowse link
G POLR3G RNA polymerase III subunit G part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:24,855,517...24,896,051
Ensembl chr 5:24,992,158...25,019,272 		JBrowse link
G POLR3GL RNA polymerase III subunit GL part_of IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:121,781,067...121,793,266
Ensembl chr 1:113,884,899...113,888,690 		JBrowse link
G POLR3H RNA polymerase III subunit H part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:22,419,887...22,438,539
Ensembl chr22:40,507,026...40,525,927 		JBrowse link
G POLR3K RNA polymerase III subunit K part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr16:37,772...44,598 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17143
    protein-containing complex 5882
      nuclear protein-containing complex 1237
        nuclear DNA-directed RNA polymerase complex 93
          RNA polymerase III complex 20
Path 2
Term Annotations click to browse term
  cellular_component 17143
    protein-containing complex 5882
      catalytic complex 1699
        transferase complex 818
          transferase complex, transferring phosphorus-containing groups 276
            RNA polymerase complex 97
              DNA-directed RNA polymerase complex 95
                nuclear DNA-directed RNA polymerase complex 93
                  RNA polymerase III complex 20
paths to the root