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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA replication factor C complex
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Accession:GO:0005663 term browser browse the term
Definition:A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.
Synonyms:exact_synonym: RFC complex;   activator 1 complex


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DNA replication factor C complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfc1 replication factor C subunit 1 ISO (PMID:9488738) RGD PMID:9488738 NCBI chr14:44,627,528...44,702,205
Ensembl chr14:44,580,216...44,702,203
JBrowse link
G Rfc2 replication factor C subunit 2 ISO
IBA
(PMID:9488738)
PMID:21873635
RGD PMID:9488738, PMID:21873635 RGD:13792537 NCBI chr12:25,130,375...25,143,480
Ensembl chr12:25,130,377...25,143,480
JBrowse link
G Rfc3 replication factor C subunit 3 ISO
IBA
(PMID:9488738)
PMID:21873635
RGD PMID:9488738, PMID:21873635 RGD:13792537 NCBI chr12:1,460,581...1,471,344
Ensembl chr12:1,460,538...1,471,357
JBrowse link
G Rfc4 replication factor C subunit 4 ISO
IBA
(PMID:9488738)
PMID:21873635
RGD PMID:9488738, PMID:21873635 RGD:13792537 NCBI chr11:81,358,592...81,373,044
Ensembl chr11:81,358,592...81,373,043
JBrowse link
G Rfc5 replication factor C subunit 5 ISO
IBA
(PMID:9488738)
PMID:21873635
RGD PMID:9488738, PMID:21873635 RGD:13792537 NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6104
      DNA replication factor C complex 5
        cytoplasmic DNA replication factor C complex 0
        nuclear DNA replication factor C complex + 0
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      organelle 13271
        non-membrane-bounded organelle 5195
          intracellular non-membrane-bounded organelle 5178
            chromosome 1423
              replication fork 73
                DNA replication factor C complex 5
                  cytoplasmic DNA replication factor C complex 0
                  nuclear DNA replication factor C complex + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.