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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear lamina
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Accession:GO:0005652 term browser browse the term
Definition:The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
Synonyms:xref: NIF_Subcellular:sao1455996588;   Wikipedia:Nuclear_lamina



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nuclear lamina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cask calcium/calmodulin dependent serine protein kinase located_in
part_of
ISO (PMID:18664494) RGD PMID:18664494 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Hlcs holocarboxylase synthetase located_in ISO (PMID:14613969) RGD PMID:14613969 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Lmnb1 lamin B1 located_in IDA
ISO
(PMID:32910914) RGD PMID:32910914 PMID:16950509 RGD:10044252 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Nup35 nucleoporin 35 IDA RGD PMID:15703211 RGD:7327145 NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130
JBrowse link
G Pcna proliferating cell nuclear antigen located_in ISO (MGI:2448855|PMID:10888872) RGD PMID:10888872 MGI:2448855 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Stx1b syntaxin 1B located_in ISO (PMID:18691641) RGD PMID:18691641 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
lamin filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif6 eukaryotic translation initiation factor 6 located_in IEA
ISO
GO_REF:0000107
(MGI:1099910|PMID:9374518)
Ensembl
RGD
PMID:9374518 GO_REF:0000107 MGI:1099910 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Lmna lamin A/C located_in IEA
ISO
GO_REF:0000107
(MGI:67980|PMID:8032679)
Ensembl
RGD
PMID:8032679 GO_REF:0000107 MGI:67980 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lmnb1 lamin B1 located_in IEA
ISO
GO_REF:0000107
(MGI:67980|PMID:8032679)
Ensembl
RGD
PMID:8032679 GO_REF:0000107 MGI:67980 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lmnb2 lamin B2 located_in ISO (MGI:67980|PMID:8032679) RGD PMID:8032679 MGI:67980 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G Lmntd2 lamin tail domain containing 2 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:196,315,112...196,320,880
Ensembl chr 1:196,315,115...196,319,156
JBrowse link
G Narf nuclear prelamin A recognition factor located_in
is_active_in
ISO
IBA
(PMID:10514485)
PMID:21873635
RGD PMID:10514485 PMID:21873635 RGD:13792537 NCBI chr10:106,519,508...106,537,494
Ensembl chr10:106,519,444...106,537,486
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      nuclear lamina 11
        lamin filament 6
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      organelle 13088
        membrane-bounded organelle 11697
          intracellular membrane-bounded organelle 11218
            nucleus 7051
              nuclear lumen 3941
                nuclear periphery 122
                  nuclear lamina 11
                    lamin filament 6
paths to the root