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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear lamina
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Accession:GO:0005652 term browser browse the term
Definition:The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
Synonyms:xref: NIF_Subcellular:sao1455996588;   Wikipedia:Nuclear_lamina


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nuclear lamina term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cask calcium/calmodulin dependent serine protein kinase ISO (PMID:18664494) RGD PMID:18664494 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Hlcs holocarboxylase synthetase ISO (PMID:14613969) RGD PMID:14613969 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Lmnb1 lamin B1 IDA RGD PMID:16950509 RGD:10044252 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Nup35 nucleoporin 35 IDA RGD PMID:15703211 RGD:7327145 NCBI chr 3:67,866,784...67,896,828
Ensembl chr 3:67,870,111...67,896,153
JBrowse link
G Pcna proliferating cell nuclear antigen ISO (MGI:2448855|PMID:10888872) RGD PMID:10888872 MGI:2448855 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Stx1b syntaxin 1B ISO (PMID:18691641) RGD PMID:18691641 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
lamin filament term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif6 eukaryotic translation initiation factor 6 IEA
ISO
GO_REF:0000107
(MGI:1099910|PMID:9374518)
Ensembl
RGD
PMID:9374518 GO_REF:0000107 MGI:1099910 NCBI chr 3:151,356,867...151,363,201
Ensembl chr 3:151,356,868...151,363,115
JBrowse link
G Lmna lamin A/C IEA
ISO
GO_REF:0000107
(MGI:67980|PMID:8032679)
Ensembl
RGD
PMID:8032679 GO_REF:0000107 MGI:67980 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lmnb1 lamin B1 IEA
ISO
GO_REF:0000107
(MGI:67980|PMID:8032679)
Ensembl
RGD
PMID:8032679 GO_REF:0000107 MGI:67980 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lmnb2 lamin B2 ISO (MGI:67980|PMID:8032679) RGD PMID:8032679 MGI:67980 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G Narf nuclear prelamin A recognition factor ISO
IBA
(PMID:10514485)
PMID:21873635
RGD PMID:10514485, PMID:21873635 RGD:13792537 NCBI chr10:110,445,765...110,463,735
Ensembl chr10:110,445,797...110,463,727
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20615
    cellular anatomical entity 20304
      nuclear lamina 10
        lamin filament 5
Path 2
Term Annotations click to browse term
  cellular_component 20615
    cellular anatomical entity 20304
      intracellular anatomical structure 14641
        intracellular organelle 12408
          intracellular membrane-bounded organelle 10518
            nucleus 6987
              nuclear lumen 3830
                nuclear periphery 123
                  nuclear lamina 10
                    lamin filament 5
paths to the root