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ONTOLOGY REPORT - ANNOTATIONS


Term:classical-complement-pathway C3/C5 convertase complex
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Accession:GO:0005601 term browser browse the term
Definition:A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.


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classical-complement-pathway C3/C5 convertase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 located_in ISO (PMID:6906228) ComplexPortal PMID:6906228 NCBI chrNW_004936727:1,602,400...1,615,974 JBrowse link
G LOC101975827 complement C4-A located_in ISO (PMID:6906228) ComplexPortal PMID:6906228 NCBI chrNW_004936727:1,556,204...1,570,084 JBrowse link

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Term Annotations click to browse term
  cellular_component 15344
    cellular anatomical entity 15229
      extracellular space 986
        classical-complement-pathway C3/C5 convertase complex 2
Path 2
Term Annotations click to browse term
  cellular_component 15344
    cellular anatomical entity 15229
      extracellular region 1517
        extracellular space 986
          classical-complement-pathway C3/C5 convertase complex 2
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