Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:classical-complement-pathway C3/C5 convertase complex
go back to main search page
Accession:GO:0005601 term browser browse the term
Definition:A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.



show annotations for term's descendants           Sort by:
 
classical-complement-pathway C3/C5 convertase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement component 2 (within H-2S) located_in
part_of
ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241
JBrowse link
G C4a complement component 4A (Rodgers blood group) located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,028,069...35,042,436
Ensembl chr17:35,028,069...35,042,440
JBrowse link
G C4b complement component 4B (Chido blood group) located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
JBrowse link
G Cfb complement factor B part_of IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28537
    cellular anatomical entity 19447
      extracellular space 2136
        classical-complement-pathway C3/C5 convertase complex 4
Path 2
Term Annotations click to browse term
  cellular_component 28537
    cellular anatomical entity 19447
      extracellular region 2882
        extracellular space 2136
          classical-complement-pathway C3/C5 convertase complex 4
paths to the root