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ONTOLOGY REPORT - ANNOTATIONS


Term:classical-complement-pathway C3/C5 convertase complex
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Accession:GO:0005601 term browser browse the term
Definition:A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.



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classical-complement-pathway C3/C5 convertase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 located_in ISO (PMID:6906228) ComplexPortal PMID:6906228 NCBI chr12:1,363,656...1,399,732
Ensembl chr12:1,363,803...1,399,728
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G LOC481722 complement C4-A located_in ISO (PMID:6906228) ComplexPortal PMID:6906228 NCBI chr12:1,433,185...1,448,056 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17796
    cellular anatomical entity 17536
      extracellular space 1416
        classical-complement-pathway C3/C5 convertase complex 2
Path 2
Term Annotations click to browse term
  cellular_component 17796
    cellular anatomical entity 17536
      extracellular region 1981
        extracellular space 1416
          classical-complement-pathway C3/C5 convertase complex 2
paths to the root