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ONTOLOGY REPORT - ANNOTATIONS

Term:fibrinogen complex
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Accession:GO:0005577 term browser browse the term
Definition:A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
Synonyms:exact_synonym: fibrinogen
 narrow_synonym: fibrinogen alpha chain;   fibrinogen beta chain;   fibrinogen gamma chain


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fibrinogen complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain part_of ISO
IEA
IBA 		(PMID:16846481), (PMID:18676163), (PMID:8910396)
GO_REF:0000002
GO_REF:0000033 		RGD
InterPro
GO_Central		 PMID:8910396 PMID:16846481 PMID:18676163 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain part_of ISO
IEA 		(PMID:16846481), (PMID:18676163), (PMID:6688356), (PMID:8910396)
GO_REF:0000002
GO_REF:0000107 		RGD
InterPro
Ensembl		 PMID:6688356 PMID:8910396 PMID:16846481 PMID:18676163 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgg fibrinogen gamma chain part_of ISO
IEA 		(PMID:16846481), (PMID:18676163), (PMID:6451630), (PMID:8470043), (PMID:8910396)
GO_REF:0000002 		RGD
InterPro		 PMID:6451630 PMID:8470043 PMID:8910396 PMID:16846481 PMID:18676163 GO_REF:0000002 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fn1 fibronectin 1 part_of IEA
ISO 		GO_REF:0000107
(PMID:20541508), (PMID:3997886) 		Ensembl
RGD		 PMID:3997886 PMID:20541508 GO_REF:0000107 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Serpinf2 serpin family F member 2 part_of ISO
IEA 		(PMID:17317851)
GO_REF:0000107 		RGD
Ensembl		 PMID:17317851 GO_REF:0000107 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996 		JBrowse link
G Thbs1 thrombospondin 1 part_of ISO
IEA 		(PMID:3997886)
GO_REF:0000107 		RGD
Ensembl		 PMID:3997886 GO_REF:0000107 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      fibrinogen complex 6
Path 2
Term Annotations click to browse term
  cellular_component 21544
    cellular anatomical structure 21390
      extracellular region 2596
        extracellular space 1678
          fibrinogen complex 6
paths to the root