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Term:fibrinogen complex
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Accession:GO:0005577 term browser browse the term
Definition:A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
Synonyms:exact_synonym: fibrinogen
 narrow_synonym: fibrinogen alpha chain;   fibrinogen beta chain;   fibrinogen gamma chain

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fibrinogen complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain part_of IBA
(PMID:16846481), (PMID:18676163), (PMID:8910396)
PMID:8910396 PMID:16846481 PMID:18676163, PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain part_of ISO (PMID:16846481), (PMID:18676163), (PMID:6688356), (PMID:8910396) RGD PMID:6688356 PMID:8910396 PMID:16846481 PMID:18676163 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain part_of ISO (PMID:16846481), (PMID:18676163), (PMID:6451630), (PMID:8470043), (PMID:8910396) RGD PMID:6451630 PMID:8470043 PMID:8910396 PMID:16846481 PMID:18676163 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fn1 fibronectin 1 part_of IEA
PMID:3997886 GO_REF:0000107 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Serpinf2 serpin family F member 2 part_of ISO (PMID:17317851) RGD PMID:17317851 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Thbs1 thrombospondin 1 part_of ISO (PMID:3997886) RGD PMID:3997886 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      fibrinogen complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      extracellular region 2497
        extracellular space 1863
          fibrinogen complex 6
paths to the root