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ONTOLOGY REPORT - ANNOTATIONS

Term:fibrinogen complex
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Accession:GO:0005577 term browser browse the term
Definition:A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
Synonyms:exact_synonym: fibrinogen
 narrow_synonym: fibrinogen alpha chain;   fibrinogen beta chain;   fibrinogen gamma chain


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fibrinogen complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain part_of ISO
IEA
IBA		 (PMID:16846481), (PMID:18676163), (PMID:8910396)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:8910396 PMID:16846481 PMID:18676163 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain part_of ISO
IEA		 (PMID:16846481), (PMID:18676163), (PMID:6688356), (PMID:8910396)
GO_REF:0000002		 RGD
InterPro		 PMID:6688356 PMID:8910396 PMID:16846481 PMID:18676163 GO_REF:0000002 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain part_of ISO (PMID:16846481), (PMID:18676163), (PMID:6451630), (PMID:8470043), (PMID:8910396) RGD PMID:6451630 PMID:8470043 PMID:8910396 PMID:16846481 PMID:18676163 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fn1 fibronectin 1 part_of IEA
ISO		 GO_REF:0000107
(PMID:20541508), (PMID:3997886)		 Ensembl
RGD		 PMID:3997886 PMID:20541508 GO_REF:0000107 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Serpinf2 serpin family F member 2 part_of ISO (PMID:17317851) RGD PMID:17317851 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Thbs1 thrombospondin 1 part_of ISO (PMID:3997886) RGD PMID:3997886 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    protein-containing complex 6433
      fibrinogen complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      extracellular region 2326
        extracellular space 1717
          fibrinogen complex 6
paths to the root