ONTOLOGY REPORT - ANNOTATIONS
Term: phosphatidylinositol-4,5-bisphosphate binding
Accession: GO:0005546
browse the term
Definition: Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
Synonyms: exact_synonym: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding; PtdIns(4,5)P2 binding
broad_synonym: PIP2 binding
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Actn2
actinin alpha 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936484:16,186,844...16,248,394
Ensembl chrNW_004936484:16,186,642...16,248,400
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Adap2
ArfGAP with dual PH domains 2
enables
ISO
PMID:12018390
UniProt
PMID:12018390
RGD:1299471
NCBI chrNW_004936538:2,767,489...2,790,080
Ensembl chrNW_004936538:2,765,596...2,790,055
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Alox15
arachidonate 15-lipoxygenase
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253
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Amer1
APC membrane recruitment protein 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936635:3,465,473...3,482,311
Ensembl chrNW_004936635:3,478,598...3,482,008
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Amer2
APC membrane recruitment protein 2
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936688:1,136,060...1,139,078
Ensembl chrNW_004936688:1,136,224...1,138,275
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Amer3
APC membrane recruitment protein 3
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936469:41,234,187...41,244,603
Ensembl chrNW_004936469:41,238,646...41,244,623
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Anxa2
annexin A2
enables
ISO IEA
RGD TreeGrafter Ensembl
PMID:14734570
GO_REF:0000107 GO_REF:0000118 RGD:1578381
NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503
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Anxa9
annexin A9
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936580:1,208,536...1,218,438
Ensembl chrNW_004936580:1,208,120...1,220,173
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Apba1
amyloid beta precursor protein binding family A member 1
ISO
RGD
PMID:9395480
RGD:727250
NCBI chrNW_004936503:5,699,580...5,770,920
Ensembl chrNW_004936503:5,699,558...5,771,030
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Asap1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
enables NOT|enables
IEA ISO
(MGI:5758807|PMID:12771146)
Ensembl MGI
PMID:12771146
GO_REF:0000107 MGI:5758807
NCBI chrNW_004936470:18,340,120...18,640,396
Ensembl chrNW_004936470:18,339,616...18,640,624
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Avil
advillin
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936646:1,930,447...1,952,069
Ensembl chrNW_004936646:1,930,656...1,948,991
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Cadps
calcium dependent secretion activator
enables
ISO
PMID:9525942
WB
PMID:9525942
RGD:10047153
NCBI chrNW_004936637:3,543,615...4,023,710
Ensembl chrNW_004936637:3,545,211...4,022,630
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Capg
capping actin protein, gelsolin like
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936712:1,793,666...1,803,621
Ensembl chrNW_004936712:1,793,480...1,806,602
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Cgas
cyclic GMP-AMP synthase
enables
ISO
(PMID:30827685)
UniProt
PMID:30827685
NCBI chrNW_004936859:797,469...807,036
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Chmp3
charged multivesicular body protein 3
ISO
RGD
PMID:12878588
RGD:1299526
NCBI chrNW_004936712:1,023,994...1,044,727
Ensembl chrNW_004936712:1,023,989...1,044,728
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Commd1
copper metabolism domain containing 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936491:7,247,160...7,421,039
Ensembl chrNW_004936491:7,247,140...7,420,921
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Dab2
DAB adaptor protein 2
enables
ISO
(MGI:2675568|PMID:12826668)
UniProt
PMID:12826668
MGI:2675568
NCBI chrNW_004936518:2,915,819...2,936,474
Ensembl chrNW_004936518:2,915,764...2,937,875
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Dnm1
dynamin 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936487:15,767,897...15,797,722
Ensembl chrNW_004936487:15,767,897...15,801,211
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Dnm2
dynamin 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936659:957,408...1,046,393
Ensembl chrNW_004936659:957,392...1,049,188
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Exoc1
exocyst complex component 1
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936482:18,148,672...18,199,481
Ensembl chrNW_004936482:18,148,674...18,199,490
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Exoc7
exocyst complex component 7
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936594:1,244,545...1,264,211
Ensembl chrNW_004936594:1,244,483...1,264,288
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Fcho2
FCH and mu domain containing endocytic adaptor 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936549:3,455,172...3,565,507
Ensembl chrNW_004936549:3,455,172...3,565,558
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Flii
FLII actin remodeling protein
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936741:1,784,802...1,796,176
Ensembl chrNW_004936741:1,783,589...1,796,168
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Frmpd4
FERM and PDZ domain containing 4
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936470:1,923,328...2,469,067
Ensembl chrNW_004936470:1,923,835...2,470,564
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Fzd7
frizzled class receptor 7
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936726:1,256,684...1,275,324
Ensembl chrNW_004936726:1,256,678...1,275,467
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Gramd2a
GRAM domain containing 2A
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936471:31,550,506...31,588,377
Ensembl chrNW_004936471:31,550,406...31,587,981
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Gsdma
gasdermin A
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936490:15,105,030...15,115,007
Ensembl chrNW_004936490:15,105,030...15,114,599
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Gsdmc
gasdermin C
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936470:18,840,455...18,856,022
Ensembl chrNW_004936470:18,843,579...18,855,639
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Gsdmd
gasdermin D
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936470:8,567,085...8,571,448
Ensembl chrNW_004936470:8,567,091...8,571,467
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Gsdme
gasdermin E
enables
ISO
(PMID:28459430)
UniProt
PMID:28459430
NCBI chrNW_004936478:1,655,487...1,720,996
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Gsn
gelsolin
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936487:9,749,755...9,802,787
Ensembl chrNW_004936487:9,764,944...9,802,841
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Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
ISO
RGD
PMID:22948144
RGD:9686140
NCBI chrNW_004936480:17,051,902...17,416,335
Ensembl chrNW_004936480:17,051,898...17,413,657
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Hip1
huntingtin interacting protein 1
NOT|enables
ISO
(PMID:14732715)
ParkinsonsUK-UCL
PMID:14732715
NCBI chrNW_004936543:2,496,301...2,569,019
Ensembl chrNW_004936543:2,522,154...2,565,376
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Hip1r
huntingtin interacting protein 1 related
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936558:1,778,862...1,804,071
Ensembl chrNW_004936558:1,778,888...1,791,610
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Jph2
junctophilin 2
enables
ISO
(PMID:24001019)
UniProt
PMID:24001019
NCBI chrNW_004936530:2,570,365...2,606,743
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Kcnj1
potassium inwardly rectifying channel subfamily J member 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936572:3,396,329...3,425,848
Ensembl chrNW_004936572:3,421,557...3,425,276
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Kcnj2
potassium inwardly rectifying channel subfamily J member 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936655:3,447,026...3,459,569
Ensembl chrNW_004936655:3,447,321...3,458,312
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Kcnq1
potassium voltage-gated channel subfamily Q member 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936794:707,122...994,206
Ensembl chrNW_004936794:707,119...994,778
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Krit1
KRIT1 ankyrin repeat containing
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936621:2,088,606...2,128,579
Ensembl chrNW_004936621:2,088,802...2,128,657
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Ldlrap1
low density lipoprotein receptor adaptor protein 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936474:10,196,228...10,219,137
Ensembl chrNW_004936474:10,196,211...10,221,777
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LOC101962737
obscurin
enables
ISO
(PMID:28826662)
UniProt
PMID:28826662
NCBI chrNW_004936864:619...33,574
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LOC101967251
profilin-2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936727:1,992,508...1,993,271
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Mapkap1
MAPK associated protein 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936487:13,511,632...13,743,022
Ensembl chrNW_004936487:13,510,592...13,743,069
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Mark1
microtubule affinity regulating kinase 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936650:1,607,480...1,672,591
Ensembl chrNW_004936650:1,605,487...1,667,297
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Mtss2
MTSS I-BAR domain containing 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936475:22,948,608...22,967,489
Ensembl chrNW_004936475:22,950,793...22,967,467
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Myo1b
myosin IB
enables
ISO
PMID:20610386
UniProt
PMID:20610386
RGD:8554686
NCBI chrNW_004936506:6,832,132...7,004,262
Ensembl chrNW_004936506:6,832,670...7,004,273
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Myo1g
myosin IG
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936478:19,788,032...19,802,546
Ensembl chrNW_004936478:19,788,031...19,802,501
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Osbpl2
oxysterol binding protein like 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936514:9,882,066...9,916,378
Ensembl chrNW_004936514:9,891,258...9,915,416
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Pard3
par-3 family cell polarity regulator
enables
ISO
PMID:18082612
UniProt
PMID:18082612
RGD:8553352
NCBI chrNW_004936574:2,472,064...3,013,590
Ensembl chrNW_004936574:2,473,675...3,013,582
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Pfn1
profilin 1
enables
ISO IEA
RGD Ensembl
PMID:16741017
GO_REF:0000107 RGD:2324852
NCBI chrNW_004936677:2,762,971...2,766,038
Ensembl chrNW_004936677:2,762,971...2,766,149
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Pfn2
profilin 2
enables
IEA
Ensembl
GO_REF:0000107
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Phlda3
pleckstrin homology like domain family A member 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936567:2,981,632...2,984,906
Ensembl chrNW_004936567:2,981,602...2,984,903
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Picalm
phosphatidylinositol binding clathrin assembly protein
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936498:13,785,638...13,885,931
Ensembl chrNW_004936498:13,784,886...13,886,167
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Pla2g4e
phospholipase A2 group IVE
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936471:5,300,932...5,370,150
Ensembl chrNW_004936471:5,302,688...5,370,182
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Plcb1
phospholipase C beta 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936485:10,548,966...11,254,139
Ensembl chrNW_004936485:10,548,966...11,253,761
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Plcd1
phospholipase C delta 1
enables
ISO IEA
RGD Ensembl
PMID:9804818
GO_REF:0000107 RGD:2301015
NCBI chrNW_004936473:27,364,404...27,387,337
Ensembl chrNW_004936473:27,364,389...27,387,412
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Plcz1
phospholipase C zeta 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936548:7,522,902...7,573,540
Ensembl chrNW_004936548:7,522,926...7,573,540
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Plekha4
pleckstrin homology domain containing A4
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936664:2,890,279...2,908,423
Ensembl chrNW_004936664:2,890,463...2,907,871
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Rab35
RAB35, member RAS oncogene family
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936668:795,477...812,187
Ensembl chrNW_004936668:800,854...810,128
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Rag2
recombination activating 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936533:1,801,207...1,807,431
Ensembl chrNW_004936533:1,801,391...1,807,431
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Rph3a
rabphilin 3A
ISO
RGD
PMID:18945677
RGD:2314874
NCBI chrNW_004936668:2,827,574...2,911,955
Ensembl chrNW_004936668:2,857,732...2,911,517
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Rs1
retinoschisin 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936844:284,938...314,524
Ensembl chrNW_004936844:284,141...314,545
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Scin
scinderin
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936795:418,874...495,990
Ensembl chrNW_004936795:418,436...495,936
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Sdcbp
syndecan binding protein
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:14,331,971...14,347,123
Ensembl chrNW_004936496:14,331,662...14,347,197
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Sdcbp2
syndecan binding protein 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936485:17,336,209...17,356,896
Ensembl chrNW_004936485:17,336,417...17,357,027
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Sestd1
SEC14 and spectrin domain containing 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936509:8,225,252...8,303,257
Ensembl chrNW_004936509:8,225,245...8,303,279
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Sh3pxd2a
SH3 and PX domains 2A
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936600:2,343,709...2,513,497
Ensembl chrNW_004936600:2,343,658...2,509,612
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Snap91
synaptosome associated protein 91
enables
ISO IEA
RGD TreeGrafter
PMID:9188501
GO_REF:0000118 RGD:13506241
NCBI chrNW_004936510:7,222,200...7,345,138
Ensembl chrNW_004936510:7,223,757...7,343,742
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Snx18
sorting nexin 18
enables
ISO
(PMID:23878278)
FlyBase
PMID:23878278
NCBI chrNW_004936480:13,108,510...13,137,550
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Snx21
sorting nexin family member 21
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936514:7,180,533...7,188,201
Ensembl chrNW_004936514:7,180,851...7,186,146
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Stxbp6
syntaxin binding protein 6
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936494:250,131...494,599
Ensembl chrNW_004936494:250,126...438,956
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Svil
supervillin
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936613:4,391,928...4,540,125
Ensembl chrNW_004936613:4,404,711...4,542,890
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Syt1
synaptotagmin 1
enables
ISO
PMID:12860971
RGD ParkinsonsUK-UCL
PMID:12860971 PMID:22447935
RGD:11079189 RGD:7205653
NCBI chrNW_004936698:65,210...575,538
Ensembl chrNW_004936698:377,179...575,802
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Syt10
synaptotagmin 10
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936607:2,940,607...2,995,178
Ensembl chrNW_004936607:2,940,466...2,994,344
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Syt3
synaptotagmin 3
enables
ISO
PMID:12860971
ParkinsonsUK-UCL
PMID:12860971
RGD:11079189
NCBI chrNW_004936889:404,534...411,885
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Syt5
synaptotagmin 5
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936886:451,400...457,093
Ensembl chrNW_004936886:449,194...457,088
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Syt7
synaptotagmin 7
enables
ISO
(MGI:5645834|PMID:25860611), (MGI:5780544|PMID:12860971)
ParkinsonsUK-UCL
PMID:12860971 PMID:25860611
MGI:5645834 MGI:5780544
NCBI chrNW_004936581:1,516,199...1,557,992
Ensembl chrNW_004936581:1,512,855...1,559,679
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Syt9
synaptotagmin 9
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936841:542,211...706,272
Ensembl chrNW_004936841:542,417...708,797
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Sytl2
synaptotagmin like 2
enables
ISO
(PMID:17182843)
UniProt
PMID:17182843
NCBI chrNW_004936498:13,577,839...13,681,782
Ensembl chrNW_004936498:13,577,795...13,681,808
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Tirap
TIR domain containing adaptor protein
enables
ISO
(MGI:4948831|PMID:16751103)
BHF-UCL
PMID:16751103
MGI:4948831
NCBI chrNW_004936572:5,926,193...5,938,621
Ensembl chrNW_004936572:5,924,158...5,938,658
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Ttpa
alpha tocopherol transfer protein
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:10,409,948...10,466,722
Ensembl chrNW_004936496:10,454,605...10,465,301
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Tulp1
TUB like protein 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936476:23,744,707...23,757,002
Ensembl chrNW_004936476:23,744,757...23,756,565
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Twf1
twinfilin actin binding protein 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936512:2,280,266...2,293,101
Ensembl chrNW_004936512:2,280,064...2,293,117
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Vil1
villin 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936569:914,511...938,481
Ensembl chrNW_004936569:914,512...938,608
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all