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ONTOLOGY REPORT - ANNOTATIONS


Term:folic acid binding
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Accession:GO:0005542 term browser browse the term
Definition:Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Synonyms:exact_synonym: folate binding;   vitamin B9 binding;   vitamin M binding


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folic acid binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6159630, PMID:6163778 RGD:1599787, RGD:7245485 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Folr1 folate receptor alpha enables IDA
ISO
(PMID:10787414), (PMID:14722620), (PMID:23851396), (PMID:2527252) RGD PMID:2527252 PMID:10787414 PMID:14722620 PMID:23851396, PMID:10751329 RGD:1358236 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Folr2 folate receptor beta enables ISO (PMID:19116913), (PMID:25015955), (PMID:4066659) RGD PMID:4066659 PMID:19116913 PMID:25015955 NCBI chr 1:166,915,045...166,933,377
Ensembl chr 1:166,915,045...166,919,302
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G Gnmt glycine N-methyltransferase TAS
IDA
RGD PMID:8278367, PMID:17158459 RGD:1545057, RGD:7242951 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Izumo1r IZUMO1 receptor, JUNO NOT|enables ISO (MGI:5568137|PMID:24739963) RGD PMID:24739963 MGI:5568137 NCBI chr 8:13,416,418...13,418,907
Ensembl chr 8:13,416,393...13,420,439
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase enables ISO (PMID:19738041), (PMID:7766710) RGD PMID:7766710 PMID:19738041 NCBI chr 8:96,564,877...96,614,386
Ensembl chr 8:96,564,877...96,614,348
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA RGD PMID:11730351 RGD:1601423 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
G Slc19a1 solute carrier family 19 member 1 enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11600421, PMID:21873635 RGD:735239, RGD:13792537 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
JBrowse link
G Slc46a1 solute carrier family 46 member 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:65,728,508...65,741,708
Ensembl chr10:65,733,991...65,740,828
JBrowse link
G Tyms thymidylate synthetase IDA RGD PMID:7537805 RGD:2317419 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uros uroporphyrinogen III synthase IDA RGD PMID:6466301 RGD:2303402 NCBI chr 1:205,755,766...205,778,170
Ensembl chr 1:205,756,640...205,777,167
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20075
    binding 17053
      modified amino acid binding 107
        folic acid binding 14
Path 2
Term Annotations click to browse term
  molecular_function 20075
    binding 17053
      ion binding 5270
        anion binding 2376
          carboxylic acid binding 188
            folic acid binding 14
paths to the root