Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:insulin-like growth factor binding
go back to main search page
Accession:GO:0005520 term browser browse the term
Definition:Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
Synonyms:exact_synonym: IGF binding


show annotations for term's descendants           Sort by:
insulin-like growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN2 cellular communication network factor 2 enables TAS (PMID:9371786) PINC PMID:9371786 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 enables IEA InterPro GO_REF:0000002 NCBI chr 2:36,355,778...36,551,135
Ensembl chr 2:36,355,778...36,551,135 		JBrowse link
G IGF1R insulin like growth factor 1 receptor enables IDA
ISS		 (PMID:1846292), (PMID:7679099) UniProt
AgBase		 PMID:1846292 PMID:7679099 GO_REF:0000024 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2R insulin like growth factor 2 receptor enables IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit enables ISO
IBA
TAS		 (PMID:1379671) RGD
GO_Central
PINC		 PMID:1379671 PMID:12446576 GO_REF:0000033 RGD:1299153 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 enables IEA
TAS		 (PMID:2454104) Ensembl
InterPro
PINC		 PMID:2454104 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 enables IEA
NAS		 (PMID:12599210) Ensembl
InterPro
UniProt		 PMID:12599210 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 enables ISO
IEA		 RGD
InterPro
Ensembl		 PMID:1709938 GO_REF:0000002 GO_REF:0000107 RGD:69857 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 enables IEA InterPro GO_REF:0000002 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 enables IEA InterPro GO_REF:0000002 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385 		JBrowse link
G IGFBPL1 insulin like growth factor binding protein like 1 enables IEA InterPro GO_REF:0000002 NCBI chr 9:38,406,528...38,424,454
Ensembl chr 9:38,406,528...38,424,454 		JBrowse link
G KAZALD1 Kazal type serine peptidase inhibitor domain 1 enables IEA InterPro GO_REF:0000002 NCBI chr10:101,061,989...101,068,131
Ensembl chr10:101,061,989...101,068,131 		JBrowse link
insulin-like growth factor I binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1R insulin like growth factor 1 receptor enables IDA
IPI		 (PMID:19578119)
(PMID:8452530)		 UniProt
BHF-UCL		 PMID:8452530 PMID:19578119 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 enables IDA
IEA
IBA		 (PMID:21550830) UniProt
TreeGrafter
GO_Central		 PMID:21550830 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 enables ISO
IBA
IEA
IDA		 (PMID:19081843) RGD
GO_Central
Ensembl
UniProt		 PMID:2538475 PMID:19081843 GO_REF:0000033 GO_REF:0000107 RGD:729148 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 enables IPI
IBA
IEA		 (PMID:10766744) BHF-UCL
GO_Central
TreeGrafter		 PMID:10766744 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 enables IBA GO_Central GO_REF:0000033 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 enables IPI
IBA		 (PMID:10766744) BHF-UCL
GO_Central		 PMID:10766744 GO_REF:0000033 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 enables ISO
IBA
IEA		 binds with low affinity RGD
GO_Central
TreeGrafter
Ensembl		 PMID:7689963 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2301726 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G INSR insulin receptor enables IPI (PMID:8452530) BHF-UCL PMID:8452530 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G ITGA6 integrin subunit alpha 6 enables IDA (PMID:22351760) UniProt PMID:22351760 NCBI chr 2:172,427,336...172,506,459
Ensembl chr 2:172,427,354...172,506,459 		JBrowse link
G ITGAV integrin subunit alpha V contributes_to IDA (PMID:19578119) BHF-UCL PMID:19578119 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITGB3 integrin subunit beta 3 contributes_to IDA (PMID:19578119) UniProt PMID:19578119 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G ITGB4 integrin subunit beta 4 contributes_to IDA (PMID:22351760) UniProt PMID:22351760 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818 		JBrowse link
G LRP2 LDL receptor related protein 2 enables ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534 		JBrowse link
insulin-like growth factor II binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF2R insulin like growth factor 2 receptor enables ISO
IEA		 RGD
Ensembl		 PMID:16407557 GO_REF:0000107 RGD:1624326 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 enables IDA
IEA
IBA		 (PMID:21550830) UniProt
TreeGrafter
GO_Central		 PMID:21550830 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 enables ISO
ISS
IEA
IBA		 RGD
UniProt
Ensembl
GO_Central		 PMID:1709938 PMID:2538475 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 RGD:69857 RGD:729148 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 enables ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:9346943 GO_REF:0000033 GO_REF:0000118 RGD:1626111 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 enables IBA GO_Central GO_REF:0000033 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 enables IBA GO_Central GO_REF:0000033 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 enables ISO
IBA
IEA
IMP		 binds with high affinity
(PMID:15308688)		 RGD
GO_Central
TreeGrafter
Ensembl
CAFA		 PMID:7689963 PMID:15308688 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2301726 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G INSR insulin receptor enables IPI (PMID:12138094) BHF-UCL PMID:12138094 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19566
    binding 17960
      protein binding 15451
        growth factor binding 150
          insulin-like growth factor binding 20
            insulin-like growth factor I binding 13
            insulin-like growth factor II binding 8
paths to the root