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ONTOLOGY REPORT - ANNOTATIONS


Term:insulin-like growth factor binding
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Accession:GO:0005520 term browser browse the term
Definition:Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
Synonyms:exact_synonym: IGF binding


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insulin-like growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccn3 cellular communication network factor 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccn4 cellular communication network factor 4 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ccn5 cellular communication network factor 5 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:160,207,969...160,219,316
Ensembl chr 3:160,207,913...160,219,331
JBrowse link
G Ccn6 cellular communication network factor 6 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:44,237,491...44,255,064
Ensembl chr20:44,237,491...44,255,064
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Esm1 endothelial cell-specific molecule 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G Htra1 HtrA serine peptidase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Htra3 HtrA serine peptidase 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:80,248,140...80,276,534
Ensembl chr14:80,248,140...80,276,534
JBrowse link
G Htra4 HtrA serine peptidase 4 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:71,784,819...71,802,765
Ensembl chr16:71,787,966...71,802,763
JBrowse link
G Igf1r insulin-like growth factor 1 receptor TAS
ISO
ISS
PR:P05017 (MGI:2679358|PMID:14566968)
(PMID:1846292), (PMID:7679099)
GO_REF:0000024
RGD
AgBase
UniProt
PMID:1846292 PMID:7679099 PMID:14566968, PMID:11572795 GO_REF:0000024 MGI:2679358, RGD:70266 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO
IBA
PR:P09535 (MGI:2679358|PMID:14566968)
PMID:21873635
RGD PMID:14566968, PMID:21873635 MGI:2679358, RGD:13792537 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:12446576, PMID:21873635 RGD:1299153, RGD:13792537 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 TAS
ISO
PR:P05017 (MGI:52244|PMID:7679139) RGD PMID:7679139, PMID:15070850 MGI:52244, RGD:1578550 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 ISO PR:P05017 (MGI:52244|PMID:7679139) RGD PMID:7679139 MGI:52244 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO PR:P05017 (MGI:52244|PMID:7679139) RGD PMID:7679139 MGI:52244 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 TAS
ISO
PR:P05017 (MGI:52244|PMID:7679139) RGD PMID:7679139, PMID:11145587, PMID:7679899 MGI:52244, RGD:61527, RGD:729004 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 IDA
ISO
IEA
MGI:96432|PR:P09535 (MGI:2679358|PMID:14566968)
GO_REF:0000002
RGD
InterPro
PMID:14566968, PMID:1709938 GO_REF:0000002 MGI:2679358, RGD:69857 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:61,395,407...61,410,812
Ensembl chr 5:61,395,408...61,410,812
JBrowse link
G Kazald1 Kazal-type serine peptidase inhibitor domain 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:264,827,739...264,831,152
Ensembl chr 1:264,827,739...264,831,151
JBrowse link
insulin-like growth factor I binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1r insulin-like growth factor 1 receptor ISO
IEA
UniProtKB:P05019 (PMID:19578119), (PMID:8452530)
GO_REF:0000107
RGD
Ensembl
PMID:8452530 PMID:19578119 GO_REF:0000107 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO
IBA
(PMID:21550830)
PMID:21873635
RGD PMID:21550830, PMID:21873635 RGD:13792537 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 IMP
IBA
ISO
IDA
PMID:21873635
(PMID:19081843)
PMID:2538475
RGD PMID:19081843, PMID:2538475, PMID:21873635, PMID:2538475 RGD:729148, RGD:13792537, RGD:729148 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO
IBA
IEA
UniProtKB:P05019 (PMID:10766744)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:10766744, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO
IBA
UniProtKB:P05019 (PMID:10766744)
PMID:21873635
RGD PMID:10766744, PMID:21873635 RGD:13792537 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 IPI
IBA
binds with low affinity
PMID:21873635
RGD
GO_Central
PMID:7689963, PMID:21873635 RGD:2301726, RGD:13792537 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Insr insulin receptor ISO
IEA
UniProtKB:P05019 (PMID:8452530)
GO_REF:0000107
RGD
Ensembl
PMID:8452530 GO_REF:0000107 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Itga6 integrin subunit alpha 6 ISO (PMID:22351760) RGD PMID:22351760 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgav integrin subunit alpha V contributes_to ISO (PMID:19578119) RGD PMID:19578119 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb3 integrin subunit beta 3 contributes_to ISO (PMID:19578119) RGD PMID:19578119 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itgb4 integrin subunit beta 4 contributes_to IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:22351760)
Ensembl
UniProt
RGD
PMID:22351760 GO_REF:0000024 GO_REF:0000107 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Lrp2 LDL receptor related protein 2 IDA PMID:16306401 ARUK-UCL PMID:16306401 RGD:14697713 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
insulin-like growth factor II binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf2r insulin-like growth factor 2 receptor IDA RGD PMID:16407557 RGD:1624326 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO
IBA
(PMID:21550830)
PMID:21873635
RGD PMID:21550830, PMID:21873635 RGD:13792537 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 IDA
IBA
IPI
PMID:21873635
PMID:2974285
PMID:2538475
RGD
GO_Central
UniProt
PMID:2538475, PMID:21873635, PMID:2974285, PMID:2538475, PMID:1709938 RGD:729148, RGD:13792537, RGD:8553840, RGD:729148, RGD:69857 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IPI
IBA
PMID:21873635 RGD
GO_Central
PMID:9346943, PMID:21873635 RGD:1626111, RGD:13792537 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 TAS
IBA
ISO
IPI
PMID:21873635
(PMID:15308688)
binds with high affinity
RGD PMID:15308688, PMID:12175646, PMID:21873635, PMID:7689963 RGD:727407, RGD:13792537, RGD:2301726 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Insr insulin receptor ISO
IEA
UniProtKB:P01344 (PMID:12138094)
GO_REF:0000107
RGD
Ensembl
PMID:12138094 GO_REF:0000107 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20486
    binding 17290
      protein binding 14416
        growth factor binding 148
          insulin-like growth factor binding 29
            insulin-like growth factor I binding 13
            insulin-like growth factor II binding 8
paths to the root