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ONTOLOGY REPORT - ANNOTATIONS


Term:protein binding
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Accession:GO:0005515 term browser browse the term
Definition:Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Synonyms:exact_synonym: protein amino acid binding
 narrow_synonym: glycoprotein binding
 alt_id: GO:0001948;   GO:0045308
 xref: MIPS_funcat:16.01;   MIPS_funcat:18.01.07;   reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3";   reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"


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  molecular_function 17874
    binding 15479
      protein binding 12270
        14-3-3 protein binding 33
        ATP-dependent protein binding 8
        CNBH domain intrinsic ligand binding 0
        FBXO family protein binding 2
        G-protein alpha-subunit binding 27
        G-protein beta-subunit binding 21
        G-protein gamma-subunit binding 2
        GDP-dissociation inhibitor binding + 4
        GTP-dependent protein binding 23
        GTPase activating protein binding 14
        MDM2/MDM4 family protein binding 9
        RBL family protein binding 0
        RHG protein domain binding 0
        S100 protein binding 16
        SMAD binding + 77
        SMC family protein binding 1
        SNARE binding + 115
        SOCS family protein binding 0
        STAT family protein binding 9
        TAP binding + 6
        TIMP family protein binding 0
        TRAIL binding 5
        Wnt-protein binding 33
        X11-like protein binding 1
        adiponectin binding 3
        alpha-catenin binding 11
        angiostatin binding 4
        antisigma factor binding 0
        apolipoprotein binding + 19
        arrestin family protein binding 10
        basal transcription machinery binding + 56
        beta-2-microglobulin binding 8
        beta-catenin binding 89
        bone sialoprotein binding 3
        calcium-dependent protein binding + 66
        calmodulin binding 201
        cell adhesion molecule binding + 513
        cell-cell adhesion mediator activity + 51
        chaperone binding 104
        clathrin binding + 58
        co-receptor binding 13
        complement binding + 23
        connexin binding 7
        copper-dependent protein binding 3
        cullin family protein binding 18
        cyclin binding 32
        cytokine binding + 135
        cytoskeletal protein binding + 1006
        delta-catenin binding 8
        denatured protein binding 2
        dynein heavy chain binding 14
        dynein intermediate chain binding 29
        dynein light chain binding 10
        dynein light intermediate chain binding 29
        dystroglycan binding 10
        endocytic targeting sequence binding 0
        enzyme binding + 2274
        extracellular matrix protein binding 5
        farnesylated protein binding 1
        fibronectin binding 28
        gamma-catenin binding 13
        glycosylated region protein binding 2
        growth factor binding + 143
        haptoglobin binding 10
        heat shock protein binding + 125
        hedgehog family protein binding 3
        hemoglobin binding + 9
        hexon binding 0
        histone binding + 203
        identical protein binding + 1923
        importin-alpha family protein binding 6
        inhibin binding 5
        insulin binding 6
        insulin receptor substrate binding 11
        ion channel binding 133
        kininogen binding + 2
        lamin binding 17
        laminin binding + 29
        misfolded protein binding 27
        modification-dependent protein binding + 148
        nodal binding 5
        opsin binding 4
        opsonin binding + 16
        p53 binding 68
        phosphatidylinositol 3-kinase binding + 32
        phosphoprotein binding + 85
        phytochrome binding 0
        poly-glutamine tract binding 0
        preprotein binding 1
        profilin binding 11
        proline-rich region binding + 20
        protein C-terminus binding 205
        protein N-terminus binding + 110
        protein antigen binding 9
        protein dimerization activity + 1094
        protein domain specific binding + 726
        protein kinase A binding + 48
        protein self-association + 57
        protein-macromolecule adaptor activity + 259
        proteoglycan binding + 37
        scaffold protein binding 57
        serpin family protein binding 1
        signaling receptor binding + 1692
        splicing factor binding 3
        sterol-dependent protein binding 0
        tapasin binding 1
        toxin-antitoxin pair type II binding 0
        transcription factor binding + 700
        translation elongation factor binding 1
        translation initiation factor binding + 34
        ubiquitin-like protein binding + 100
        unfolded protein binding 129
        very-low-density lipoprotein particle binding 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.