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ONTOLOGY REPORT - ANNOTATIONS


Term:protein binding
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Accession:GO:0005515 term browser browse the term
Definition:Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Synonyms:exact_synonym: protein amino acid binding
 narrow_synonym: glycoprotein binding
 alt_id: GO:0001948;   GO:0045308
 xref: reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3";   reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"


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  molecular_function 13768
    binding 13014
      protein binding 12587
        14-3-3 protein binding 32
        ATP-dependent protein binding 11
        CNBH domain intrinsic ligand binding 0
        FBXO family protein binding 2
        G-protein alpha-subunit binding 40
        G-protein beta-subunit binding 10
        G-protein gamma-subunit binding 2
        GDP-dissociation inhibitor binding + 8
        GTP-dependent protein binding 22
        GTPase activating protein binding 19
        MDM2/MDM4 family protein binding 9
        RBL family protein binding 0
        RHG protein domain binding 0
        S100 protein binding 12
        SMAD binding + 79
        SMC family protein binding 0
        SNARE binding + 85
        SOCS family protein binding 0
        STAT family protein binding 7
        TAP binding + 3
        TIMP family protein binding 0
        TRAIL binding 1
        Wnt-protein binding 25
        X11-like protein binding 1
        adiponectin binding 3
        alpha-catenin binding 11
        angiostatin binding 4
        antisigma factor binding 0
        apolipoprotein binding + 18
        arrestin family protein binding 10
        basal transcription machinery binding + 47
        beta-2-microglobulin binding 3
        beta-catenin binding 83
        bone sialoprotein binding 1
        calcium-dependent protein binding + 69
        calmodulin binding 79
        cell adhesion molecule binding + 212
        chaperone binding 90
        clathrin binding + 35
        co-receptor binding 9
        complement binding + 16
        connexin binding 7
        copper-dependent protein binding 3
        cullin family protein binding 16
        cyclin binding 29
        cytokine binding + 107
        cytoskeletal protein binding + 684
        delta-catenin binding 7
        denatured protein binding 0
        dynein heavy chain binding 5
        dynein intermediate chain binding 11
        dynein light chain binding 6
        dynein light intermediate chain binding 5
        dystroglycan binding 10
        endocytic targeting sequence binding 0
        enzyme binding + 1976
        extracellular matrix protein binding 4
        farnesylated protein binding 1
        fibronectin binding 29
        gamma-catenin binding 12
        glycosylated region protein binding 0
        growth factor binding + 116
        haptoglobin binding 1
        heat shock protein binding + 126
        hedgehog family protein binding 4
        hemoglobin binding + 4
        hexon binding 0
        histone binding + 161
        identical protein binding + 2035
        importin-alpha family protein binding 9
        inhibin binding 7
        insulin binding 7
        insulin receptor substrate binding 10
        ion channel binding 139
        kininogen binding + 3
        lamin binding 16
        laminin binding + 30
        misfolded protein binding 12
        modification-dependent protein binding + 138
        nodal binding 2
        opsin binding 5
        opsonin binding + 11
        p53 binding 69
        phosphatidylinositol 3-kinase binding + 35
        phosphoprotein binding + 95
        phytochrome binding 0
        poly-glutamine tract binding 0
        preprotein binding 3
        profilin binding 11
        proline-rich region binding + 20
        protein C-terminus binding 227
        protein N-terminus binding + 126
        protein antigen binding 9
        protein dimerization activity + 746
        protein domain specific binding + 727
        protein kinase A binding + 45
        protein self-association + 65
        protein-macromolecule adaptor activity + 148
        proteoglycan binding + 34
        scaffold protein binding 72
        serpin family protein binding 0
        signaling receptor binding + 1205
        splicing factor binding 4
        sterol-dependent protein binding 0
        tapasin binding 2
        toxin-antitoxin pair type II binding 0
        transcription factor binding + 605
        translation elongation factor binding 1
        translation initiation factor binding + 26
        ubiquitin-like protein binding + 69
        unfolded protein binding 29
        very-low-density lipoprotein particle binding 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.