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ONTOLOGY REPORT - ANNOTATIONS

Term:L-glutamate transmembrane transporter activity
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Accession:GO:0005313 term browser browse the term
Definition:Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.
Synonyms:narrow_synonym: glutamate/aspartate porter activity;   glutamate/aspartate:sodium symporter activity
 broad_synonym: L-glutamate transporter activity;   glutamate transmembrane transporter activity
 xref: RHEA:66336;   Reactome:R-HSA-5624256 "Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+";   reactome:R-HSA-210444 "L-Glutamate loading of synaptic vesicle";   reactome:R-HSA-428052 "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+"


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L-glutamate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grik1 glutamate ionotropic receptor kainate type subunit 1 enables ISO MGI:2176347 (PMID:14715943) RGD PMID:14715943 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 enables IDA
IBA		 PMID:19169251
GO_REF:0000033		 GO_Central PMID:19169251 GO_REF:0000033, RGD:152025512 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 enables IDA
ISO
IBA		 MGI:2655190 (PMID:11030592), (PMID:14715943), (PMID:15009636), (PMID:15471567)
GO_REF:0000033
(PMID:12562531), (PMID:21123949), (PMID:7521911), (PMID:7914198)		 RGD
GO_Central		 PMID:7521911 PMID:7914198 PMID:11030592 PMID:12562531 PMID:14715943 More... GO_REF:0000033, RGD:1599319 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 enables ISO
IBA		 (PMID:7521911)
(PMID:15009636), (PMID:24307171)
GO_REF:0000033		 RGD
GO_Central		 PMID:7521911 PMID:15009636 PMID:24307171 GO_REF:0000033 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 enables TAS
IBA
ISO
IDA		 GO_REF:0000033
(PMID:7521911)		 GO_Central
RGD		 PMID:7521911 PMID:11950769 PMID:15242733 GO_REF:0000033, RGD:727361, RGD:1642939 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 enables TAS
ISO
IBA
IEA		 MGI:3027689 (PMID:14715943)
GO_REF:0000033
(PMID:7791878)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:7791878 PMID:14715943 PMID:11950769 GO_REF:0000033 GO_REF:0000107, RGD:727361 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
G Slc1a7 solute carrier family 1 member 7 enables IBA
ISO		 GO_REF:0000033
(PMID:24307171)		 GO_Central
RGD		 PMID:24307171 GO_REF:0000033 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
G Slc25a13 solute carrier family 25 member 13 enables IEA
ISO		 GO_REF:0000107
MGI:3028639 (PMID:14701727)		 Ensembl
RGD		 PMID:14701727 GO_REF:0000107 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902 		JBrowse link
G Slc25a18 solute carrier family 25 member 18 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:154,000,808...154,021,373
Ensembl chr 4:154,000,990...154,021,372 		JBrowse link
G Slc25a22 solute carrier family 25 member 22 enables ISO
IMP		 (PMID:11897791)
PMID:19584051		 RGD PMID:11897791 PMID:19584051 RGD:151665733 NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331 		JBrowse link
G Slc38a6 solute carrier family 38, member 6 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:7510057|PMID:33503881)		 UniProt
Ensembl
RGD		 PMID:33503881 GO_REF:0000024 GO_REF:0000107 MGI:7510057 NCBI chr 6:91,987,652...92,076,416
Ensembl chr 6:91,987,672...92,049,935 		JBrowse link
cystine:glutamate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 enables ISO (PMID:11417227), (PMID:15151999), (PMID:34120018), (PMID:35245456), (PMID:35352032) RGD PMID:11417227 PMID:15151999 PMID:34120018 PMID:35245456 PMID:35352032 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
high-affinity L-glutamate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a1 solute carrier family 1 member 1 enables ISS
ISO		 GO_REF:0000024
(PMID:26690923), (PMID:8857541)		 UniProt
RGD		 PMID:8857541 PMID:26690923 GO_REF:0000024 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 enables TAS
IMP
ISO
IDA
IEA		 (PMID:26690923)
PMID:1448170
(MGI:1098956|PMID:9373176)
GO_REF:0000107		 RGD
Ensembl		 PMID:9373176 PMID:26690923 PMID:11896154 PMID:10899959 PMID:1448170 GO_REF:0000107 MGI:1098956, RGD:619547, RGD:1642938, RGD:70006 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 enables IMP
IEA
ISS
ISO		 PMID:1279699
GO_REF:0000107
GO_REF:0000024
(PMID:26690923), (PMID:28032905), (PMID:8123008)
MGI:1931872 (PMID:14723703), (PMID:15390100), (PMID:7903437)		 Ensembl
UniProt
RGD		 PMID:7903437 PMID:8123008 PMID:14723703 PMID:15390100 PMID:26690923 More... GO_REF:0000024 GO_REF:0000107, RGD:1642938, RGD:70007 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 enables IDA PMID:26690923 UniProt PMID:26690923 RGD:12907562 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
L-glutamate uniporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc17a6 solute carrier family 17 member 6 enables IDA
ISO
IEA		 PMID:32439795
PMID:27133463
PMID:11502256
(PMID:11698620)
PMID:29642010
PMID:11698619
PMID:17046815
GO_REF:0000107
(PMID:11432869)		 RGD
Ensembl		 PMID:11432869 PMID:11698620 PMID:32439795 PMID:27133463 PMID:11502256 More... GO_REF:0000107, RGD:152025520, RGD:152025528, RGD:13702232, RGD:152025529, RGD:151665720, RGD:151665738 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 enables IDA
ISO		 PMID:29642010
PMID:10938000
PMID:18080752
(MGI:6838939|PMID:25433636), (MGI:7275317|PMID:29642010)		 RGD PMID:25433636 PMID:29642010 PMID:29642010 PMID:10938000 PMID:18080752 MGI:6838939 MGI:7275317, RGD:152025529, RGD:12050146, RGD:152025516 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 enables IDA
ISO
ISS		 PMID:12388773
(PMID:12151341)
PMID:27133463
GO_REF:0000024
PMID:12097496
(MGI:7260375|PMID:18080752), (PMID:12384506)		 RGD
UniProt		 PMID:12151341 PMID:12384506 PMID:18080752 PMID:12388773 PMID:27133463 More... GO_REF:0000024 MGI:7260375, RGD:625707, RGD:152025528, RGD:628464 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20733
    transporter activity 1240
      transmembrane transporter activity 1142
        amino acid transmembrane transporter activity 103
          acidic amino acid transmembrane transporter activity 20
            L-glutamate transmembrane transporter activity 15
              L-glutamate uniporter activity 3
              L-glutamate:proton antiporter activity 0
              cystine:glutamate antiporter activity 1
              high-affinity L-glutamate transmembrane transporter activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20733
    transporter activity 1240
      transmembrane transporter activity 1142
        organic acid transmembrane transporter activity 188
          carboxylic acid transmembrane transporter activity 187
            L-amino acid transmembrane transporter activity 70
              L-glutamate transmembrane transporter activity 15
                L-glutamate uniporter activity 3
                L-glutamate:proton antiporter activity 0
                cystine:glutamate antiporter activity 1
                high-affinity L-glutamate transmembrane transporter activity 4
paths to the root