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ONTOLOGY REPORT - ANNOTATIONS

Term:amino acid:sodium symporter activity
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Accession:GO:0005283 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).
Synonyms:exact_synonym: sodium/excitatory amino acid symporter activity
 narrow_synonym: glutamate/aspartate:sodium symporter activity;   insulin-activated sodium/amino acid transporter activity;   insulin-activated sodium:amino acid symporter activity;   isoleucine/valine:sodium symporter activity
 broad_synonym: sodium/amino acid transporter activity;   sodium/excitatory amino acid cotransporter activity
 related_synonym: threonine/serine:sodium symporter activity
 alt_id: GO:0005284;   GO:0005285


show annotations for term's descendants           Sort by:
amino acid:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a1 solute carrier family 38, member 1 enables IDA PMID:11692272 UniProt PMID:11692272 RGD:152995572 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 enables IDA
IEA
ISO 		PMID:12054432
GO_REF:0000107
(PMID:15774260) 		Ensembl
RGD		 PMID:15774260 PMID:12054432 GO_REF:0000107, RGD:152995574 NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 enables ISO
IEA 		(PMID:33928121)
GO_REF:0000107 		RGD
Ensembl		 PMID:33928121 GO_REF:0000107 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:128,144,807...128,202,995 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 enables ISO (PMID:30270321) RGD PMID:30270321 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 enables ISO
IEA 		(PMID:30270321), (PMID:8420981)
GO_REF:0000107 		RGD
Ensembl		 PMID:8420981 PMID:30270321 GO_REF:0000107 NCBI chr 4:148,853,557...148,968,895
Ensembl chr 4:147,297,969...147,413,443 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 enables ISO
IEA 		(PMID:17502375)
GO_REF:0000107
(PMID:30270321), (PMID:8420981) 		RGD
Ensembl		 PMID:8420981 PMID:17502375 PMID:30270321 GO_REF:0000107 NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 enables ISO
IEA 		(PMID:8010975)
GO_REF:0000107
(PMID:1465453), (PMID:30270321), (PMID:9375654) 		RGD
Ensembl		 PMID:1465453 PMID:8010975 PMID:9375654 PMID:30270321 GO_REF:0000107 NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
alanine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a1 solute carrier family 38, member 1 enables IDA PMID:11692272 UniProt PMID:11692272 RGD:152995572 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 enables IDA PMID:10811809
PMID:18319257
PMID:19589777 		UniProt PMID:10811809 PMID:18319257 PMID:19589777 RGD:68921, RGD:152995546, RGD:152995570 NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 enables ISO
IEA
ISS 		(PMID:11414754)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11414754 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:128,144,807...128,202,995 		JBrowse link
gamma-aminobutyric acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a1 solute carrier family 6 member 1 enables IDA
IEA
ISO
IBA 		GO_REF:0000002
(PMID:16150932), (PMID:30270321), (PMID:8420981)
GO_REF:0000033
PMID:18054861
PMID:21775701
(PMID:10973981), (PMID:30132828) 		InterPro
RGD
GO_Central		 PMID:8420981 PMID:10973981 PMID:16150932 PMID:30132828 PMID:30270321 More... GO_REF:0000002 GO_REF:0000033, RGD:632739, RGD:152025510, RGD:152025506 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 enables IDA
IEA
ISO
IBA 		GO_REF:0000107
GO_REF:0000002
(PMID:30270321), (PMID:8420981)
GO_REF:0000033
(PMID:7874447)
PMID:1497897 		Ensembl
InterPro
RGD
GO_Central		 PMID:7874447 PMID:8420981 PMID:30270321 PMID:1400419 PMID:1497897 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727560, RGD:729938 NCBI chr 4:148,853,557...148,968,895
Ensembl chr 4:147,297,969...147,413,443 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 enables TAS
ISO
IBA
ISS
IEA 		(PMID:1517200)
GO_REF:0000033
GO_REF:0000024
(PMID:10358010)
(PMID:7589472), (PMID:7861179)
GO_REF:0000002 		RGD
GO_Central
UniProt
InterPro		 PMID:1517200 PMID:7589472 PMID:7861179 PMID:10358010 PMID:15073174 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033, RGD:1303365 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 enables IDA
ISO
IBA
IEA 		(PMID:22896705), (PMID:30270321), (PMID:8420981)
GO_REF:0000033
(PMID:17502375), (PMID:22932902)
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:8420981 PMID:17502375 PMID:22896705 PMID:22932902 PMID:30270321 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727560, RGD:152025533 NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 enables IEA
ISO
IBA
IDA 		GO_REF:0000107
(PMID:30270321)
GO_REF:0000033
PMID:18501699 		Ensembl
RGD
GO_Central		 PMID:30270321 PMID:18501699 GO_REF:0000033 GO_REF:0000107, RGD:30309916 NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc6a8 solute carrier family 6 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979 		JBrowse link
glutamate:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a1 solute carrier family 1 member 1 enables IDA
ISO
IBA
IEA 		(PMID:8857541)
GO_REF:0000033
(PMID:12119102)
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:8857541 PMID:12119102 PMID:16128593 GO_REF:0000033 GO_REF:0000107, RGD:1599319 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 enables IDA
ISO
ISS
IBA
IEA 		PMID:1448170
(PMID:15265858)
GO_REF:0000024
GO_REF:0000033
(PMID:7698742)
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:7698742 PMID:15265858 PMID:1448170 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:70006 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 enables IMP
ISO
ISS
IBA
IEA 		PMID:1279699
(PMID:20477940), (PMID:8123008)
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:8123008 PMID:20477940 PMID:1279699 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:70007 NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 enables ISO
IBA 		(PMID:7791878)
GO_REF:0000033 		RGD
GO_Central		 PMID:7791878 GO_REF:0000033 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
G Slc1a7 solute carrier family 1 member 7 enables ISO
IEA
IBA 		(PMID:9108121)
GO_REF:0000107
(PMID:16973698), (PMID:32233906)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:9108121 PMID:16973698 PMID:32233906 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134 		JBrowse link
glycine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a1 solute carrier family 38, member 1 enables IDA PMID:11692272 UniProt PMID:11692272 RGD:152995572 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc6a5 solute carrier family 6 member 5 enables IDA
IBA
ISO 		PMID:8226790
GO_REF:0000033
(PMID:10381548), (PMID:10606742), (PMID:16751771), (PMID:31370103), (PMID:9845349) 		GO_Central
RGD		 PMID:9845349 PMID:10381548 PMID:10606742 PMID:16751771 PMID:31370103 More... GO_REF:0000033, RGD:730010 NCBI chr 1:99,645,389...99,697,016
Ensembl chr 1:99,645,389...99,697,010 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 enables IDA
IEA
ISO 		PMID:1534013
GO_REF:0000107
(PMID:1618338)
PMID:16181645
(PMID:8183239) 		Ensembl
RGD		 PMID:1618338 PMID:8183239 PMID:1534013 PMID:16181645 GO_REF:0000107, RGD:632882, RGD:151665718 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
high-affinity L-glutamate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a1 solute carrier family 1 member 1 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:26690923), (PMID:8857541) 		UniProt
Ensembl
RGD		 PMID:8857541 PMID:26690923 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 enables TAS
ISO
IEA
IDA
IMP 		(PMID:9373176)
GO_REF:0000107
PMID:1448170
(PMID:26690923) 		RGD
Ensembl		 PMID:9373176 PMID:26690923 PMID:11896154 PMID:1448170 PMID:10899959 GO_REF:0000107, RGD:619547, RGD:70006, RGD:1642938 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 enables IMP
ISO
IEA
ISS 		MGI:1931872 (PMID:14723703), (PMID:15390100), (PMID:7903437)
GO_REF:0000107
(PMID:26690923), (PMID:28032905), (PMID:8123008)
GO_REF:0000024
PMID:1279699 		RGD
Ensembl
UniProt		 PMID:7903437 PMID:8123008 PMID:14723703 PMID:15390100 PMID:26690923 More... GO_REF:0000024 GO_REF:0000107, RGD:1642938, RGD:70007 NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 enables IDA PMID:26690923 UniProt PMID:26690923 RGD:12907562 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
L-asparagine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a7 solute carrier family 38, member 7 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28416685) 		UniProt
Ensembl
RGD		 PMID:28416685 GO_REF:0000024 GO_REF:0000107 NCBI chr19:9,215,336...9,231,592
Ensembl chr19:9,209,257...9,225,454 		JBrowse link
L-glutamine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a7 solute carrier family 38, member 7 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21511949), (PMID:28416685)
(PMID:28416685) 		UniProt
Ensembl
RGD		 PMID:21511949 PMID:28416685 GO_REF:0000024 GO_REF:0000107 NCBI chr19:9,215,336...9,231,592
Ensembl chr19:9,209,257...9,225,454 		JBrowse link
neutral L-amino acid:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a1 solute carrier family 38, member 1 enables IDA PMID:12684517
PMID:10660562
PMID:11756489 		ARUK-UCL
UniProt		 PMID:12684517 PMID:10660562 PMID:11756489 RGD:1299220, RGD:68922, RGD:70402 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 enables ISO
IEA
IDA 		(PMID:10930503)
GO_REF:0000107
PMID:16629640
PMID:27355203
PMID:11756489
PMID:10747860
PMID:10859363 		RGD
Ensembl		 PMID:10930503 PMID:16629640 PMID:27355203 PMID:11756489 PMID:10747860 More... GO_REF:0000107, RGD:152995548, RGD:152995578, RGD:70402, RGD:68920, RGD:1299212 NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc38a3 solute carrier family 38, member 3 enables IDA PMID:16249471 UniProt PMID:16249471 RGD:152995568 NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:108,323,894...108,339,988 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 enables ISO
IEA
ISS
IDA 		(PMID:11342143), (PMID:11414754), (PMID:19015196)
GO_REF:0000107
(PMID:23451088)
GO_REF:0000024
PMID:11118514 		RGD
Ensembl
UniProt		 PMID:11342143 PMID:11414754 PMID:19015196 PMID:23451088 PMID:11118514 GO_REF:0000024 GO_REF:0000107, RGD:631978 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:128,144,807...128,202,995 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:16185194)
(PMID:16226721) 		UniProt
Ensembl
RGD		 PMID:16185194 PMID:16226721 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
neutral L-amino acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a18 solute carrier family 6 member 18 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19478081), (PMID:20377526), (PMID:26240152) 		UniProt
Ensembl
RGD		 PMID:19478081 PMID:20377526 PMID:26240152 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925 		JBrowse link
neutral, basic amino acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a14 solute carrier family 6 member 14 enables ISO
IBA 		(PMID:10446133)
GO_REF:0000033 		RGD
GO_Central		 PMID:10446133 GO_REF:0000033 NCBI chr  X:112,314,643...112,375,412
Ensembl chr  X:112,314,691...112,375,096 		JBrowse link
proline:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a1 solute carrier family 38, member 1 enables IDA PMID:11692272 UniProt PMID:11692272 RGD:152995572 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 enables IDA PMID:11716780 UniProt PMID:11716780 RGD:152995560 NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 enables ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:17931606)
GO_REF:0000033 		UniProt
Ensembl
RGD
GO_Central		 PMID:17931606 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Slc6a20a solute carrier family 6 member 20a enables IDA
IBA
ISS
IEA
ISO 		PMID:15632147
GO_REF:0000033
GO_REF:0000024
GO_REF:0000107
(PMID:33428810) 		GO_Central
UniProt
Ensembl
RGD		 PMID:33428810 PMID:15632147 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:8554670 NCBI chr 8:132,159,768...132,200,016
Ensembl chr 8:123,281,472...123,322,573 		JBrowse link
G Slc6a20b solute carrier family 6 member 20b enables IDA
IBA
ISS 		PMID:15632147
GO_REF:0000033
GO_REF:0000024 		GO_Central
UniProt		 PMID:15632147 GO_REF:0000024 GO_REF:0000033, RGD:8554670 NCBI chr 8:123,234,731...123,278,306
Ensembl chr 8:123,234,714...123,278,680 		JBrowse link
G Slc6a7 solute carrier family 6 member 7 enables ISS
IBA
IDA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
PMID:10414958
GO_REF:0000107
(PMID:7651355) 		UniProt
GO_Central
Ensembl
RGD		 PMID:7651355 PMID:10414958 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:152025513 NCBI chr18:54,448,464...54,467,319
Ensembl chr18:54,448,464...54,467,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21054
    transporter activity 1274
      transmembrane transporter activity 1165
        amino acid transmembrane transporter activity 108
          amino acid:monoatomic cation symporter activity 29
            amino acid:sodium symporter activity 24
              alanine:sodium symporter activity + 4
              gamma-aminobutyric acid:sodium:chloride symporter activity 6
              glutamate:sodium symporter activity + 5
              neutral L-amino acid:sodium symporter activity + 8
              neutral L-amino acid:sodium:chloride symporter activity 1
              neutral, basic amino acid:sodium:chloride symporter activity 1
              proline:sodium symporter activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21054
    transporter activity 1274
      transmembrane transporter activity 1165
        monoatomic ion transmembrane transporter activity 771
          monoatomic cation transmembrane transporter activity 652
            metal ion transmembrane transporter activity 464
              sodium ion transmembrane transporter activity 175
                solute:sodium symporter activity 85
                  amino acid:sodium symporter activity 24
                    alanine:sodium symporter activity + 4
                    gamma-aminobutyric acid:sodium:chloride symporter activity 6
                    glutamate:sodium symporter activity + 5
                    neutral L-amino acid:sodium symporter activity + 8
                    neutral L-amino acid:sodium:chloride symporter activity 1
                    neutral, basic amino acid:sodium:chloride symporter activity 1
                    proline:sodium symporter activity 6
paths to the root