Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:intracellularly cyclic nucleotide-activated monoatomic cation channel activity
go back to main search page
Accession:GO:0005221 term browser browse the term
Definition:Enables the transmembrane transfer of a monoatomic cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
Synonyms:exact_synonym: intracellular cyclic nucleotide activated monoatomic cation channel activity
 broad_synonym: intracellular cyclic nucleotide activated cation channel activity
 xref: reactome:R-HSA-2514867 "cGMP:CNG transports Na+ and Ca2+ into the rod outer segment"


show annotations for term's descendants           Sort by:
intracellularly cyclic nucleotide-activated monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 enables IEA InterPro GO_REF:0000002 NCBI chr 8:37,896,460...37,968,935
Ensembl chr 8:37,896,459...37,969,344 		JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 enables IEA InterPro GO_REF:0000002 NCBI chr  X:123,115,980...123,130,043
Ensembl chr  X:123,115,975...123,129,840 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 enables IEA InterPro GO_REF:0000002 NCBI chr 3:55,872,607...55,936,516
Ensembl chr 3:55,874,250...55,922,979 		JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 enables ISO
IEA		 RGD
InterPro		 PMID:7522325 GO_REF:0000002 RGD:632400 NCBI chr 9:3,430,995...3,438,411
Ensembl chr 9:3,431,340...3,442,426 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 enables IEA InterPro GO_REF:0000002 NCBI chr 6:19,752,734...19,865,830 JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 enables IEA InterPro GO_REF:0000002 NCBI chr 4:50,112,927...50,263,264
Ensembl chr 4:50,112,927...50,263,222 		JBrowse link
G PEX5L peroxisomal biogenesis factor 5 like enables ISO PMID:19555650 UniProt PMID:19555650 RGD:8553454 NCBI chr13:117,832,199...118,088,383
Ensembl chr13:117,833,705...118,088,277 		JBrowse link
intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:29,439,294...29,808,855
Ensembl chr16:29,439,264...29,808,993 		JBrowse link
intracellularly cAMP-activated cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:37,896,460...37,968,935
Ensembl chr 8:37,896,459...37,969,344 		JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 enables ISO PMID:1697649
PMID:15134638
PMID:10377344		 RGD
UniProt		 PMID:1697649 PMID:10377344 PMID:15134638 PMID:22786723 RGD:1298763 RGD:405650282 RGD:632392 RGD:7241219 NCBI chr  X:123,115,980...123,130,043
Ensembl chr  X:123,115,975...123,129,840 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:55,872,607...55,936,516
Ensembl chr 3:55,874,250...55,922,979 		JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 enables ISO
IBA		 RGD
GO_Central		 PMID:22786723 GO_REF:0000033 RGD:7241219 NCBI chr 9:3,430,995...3,438,411
Ensembl chr 9:3,431,340...3,442,426 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 enables ISO PMID:10377344
PMID:15134638
(PMID:34699778)		 RGD
UniProt		 PMID:10377344 PMID:15134638 PMID:22786723 PMID:34699778 RGD:405650282 RGD:632392 RGD:7241219 NCBI chr 6:19,752,734...19,865,830 JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:50,112,927...50,263,264
Ensembl chr 4:50,112,927...50,263,222 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:29,439,294...29,808,855
Ensembl chr16:29,439,264...29,808,993 		JBrowse link
G HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:77,708,159...77,730,881
Ensembl chr 2:77,708,162...77,730,881 		JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 NOT|enables ISO (PMID:15923185) UniProt PMID:15923185 NCBI chr 4:94,545,919...94,560,105
Ensembl chr 4:94,547,416...94,560,106 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:60,010,396...60,052,258
Ensembl chr 7:60,010,283...60,050,689 		JBrowse link
intracellularly cGMP-activated cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 enables ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:18048449 PMID:21809342 GO_REF:0000033 GO_REF:0000107 RGD:6902901 RGD:6902904 NCBI chr 8:37,896,460...37,968,935
Ensembl chr 8:37,896,459...37,969,344 		JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 enables ISO PMID:1697649
PMID:27405959
PMID:9878057		 RGD
UniProt		 PMID:1697649 PMID:9878057 PMID:18048449 PMID:22786723 PMID:27405959 RGD:1298763 RGD:401966869 RGD:405650338 RGD:6902904 RGD:7241219 NCBI chr  X:123,115,980...123,130,043
Ensembl chr  X:123,115,975...123,129,840 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 enables ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:11387380 GO_REF:0000033 GO_REF:0000107 RGD:1600869 NCBI chr 3:55,872,607...55,936,516
Ensembl chr 3:55,874,250...55,922,979 		JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 enables ISO
IBA		 RGD
GO_Central		 PMID:22786723 GO_REF:0000033 RGD:7241219 NCBI chr 9:3,430,995...3,438,411
Ensembl chr 9:3,431,340...3,442,426 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 enables ISO PMID:27405959
PMID:9878057
(PMID:24164424), (PMID:34699778)		 RGD
UniProt		 PMID:9878057 PMID:21809342 PMID:22786723 PMID:24164424 PMID:27405959 More... RGD:401966869 RGD:405650338 RGD:6902901 RGD:7241219 NCBI chr 6:19,752,734...19,865,830 JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:50,112,927...50,263,264
Ensembl chr 4:50,112,927...50,263,222 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18634
    transporter activity 1193
      transmembrane transporter activity 1096
        monoatomic ion transmembrane transporter activity 722
          monoatomic ion channel activity 439
            ligand-gated monoatomic ion channel activity 185
              intracellularly ligand-gated monoatomic ion channel activity 32
                intracellularly cyclic nucleotide-activated monoatomic cation channel activity 12
                  intracellularly cAMP-activated cation channel activity + 10
                  intracellularly cGMP-activated cation channel activity 7
Path 2
Term Annotations click to browse term
  molecular_function 18634
    transporter activity 1193
      transmembrane transporter activity 1096
        passive transmembrane transporter activity 499
          channel activity 499
            gated channel activity 327
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 185
                  cyclic nucleotide-activated monoatomic ion channel activity 12
                    intracellularly cyclic nucleotide-activated monoatomic cation channel activity 12
                      intracellularly cAMP-activated cation channel activity + 10
                      intracellularly cGMP-activated cation channel activity 7
paths to the root