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ONTOLOGY REPORT - ANNOTATIONS


Term:hormone activity
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Accession:GO:0005179 term browser browse the term
Definition:The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
Comment:Also consider annotating to 'receptor agonist activity ; GO:0048018'.
Synonyms:narrow_synonym: cAMP generating peptide activity;   glycopeptide hormone;   lipopeptide hormone;   peptide hormone


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hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1600115
G Adm2 adrenomedullin 2 JBrowse link 7 130,296,895 130,298,641 RGD:1304019
G Agrp agouti related neuropeptide JBrowse link 19 37,525,941 37,584,875 RGD:1625226
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8553767
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:1624291
RGD:1600115
G Bmp10 bone morphogenetic protein 10 JBrowse link 4 119,224,906 119,230,534 RGD:1624291
RGD:1600115
G C1qtnf12 C1q and TNF related 12 JBrowse link 5 173,390,901 173,395,276 RGD:1624291
RGD:13792537
G C1qtnf9 C1q and TNF related 9 JBrowse link 15 41,069,579 41,080,961 RGD:1624291
RGD:1600115
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1600115
G Calcb calcitonin-related polypeptide, beta JBrowse link 1 184,271,116 184,276,480 RGD:1600115
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:625521
RGD:13792537
RGD:1626109
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:1624291
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:1624291
G Dio2 iodothyronine deiodinase 2 JBrowse link 6 114,475,156 114,489,443 RGD:1600115
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
RGD:1600115
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1624291
RGD:1600115
G Edn3 endothelin 3 JBrowse link 3 172,856,730 172,879,276 RGD:1624291
G Enho energy homeostasis associated JBrowse link 5 58,018,039 58,019,836 RGD:1624291
RGD:1600115
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1600115
G Erfe erythroferrone JBrowse link 9 98,505,136 98,513,005 RGD:1624291
RGD:13792537
RGD:1600115
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:1624291
G Fndc5 fibronectin type III domain containing 5 JBrowse link 5 147,323,240 147,330,266 RGD:1600115
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:13792537
G Galp galanin-like peptide JBrowse link 1 71,352,417 71,374,457 RGD:1600115
G Gast gastrin JBrowse link 10 88,245,532 88,248,485 RGD:632782
RGD:13792537
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:728574
RGD:1600115
RGD:13792537
RGD:2315021
RGD:1627653
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624960
RGD:13792537
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624382
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:1600115
G Gpha2 glycoprotein hormone subunit alpha 2 JBrowse link 1 221,594,110 221,597,297 RGD:1600115
G Gphb5 glycoprotein hormone subunit beta 5 JBrowse link 6 98,380,500 98,383,049 RGD:13792537
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1600115
RGD:1624291
G Iapp islet amyloid polypeptide JBrowse link 4 176,509,863 176,517,903 RGD:1625223
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1580473
RGD:1600115
RGD:1624291
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1600115
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:1600115
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:1600115
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:1600115
G Inhbc inhibin subunit beta C JBrowse link 7 70,648,005 70,661,475 RGD:1600115
G Inhbe inhibin subunit beta E JBrowse link 7 70,641,423 70,642,848 RGD:1600115
G Ins1 insulin 1 JBrowse link 1 272,799,784 272,800,351 RGD:1600115
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
RGD:1600115
G Insl3 insulin-like 3 JBrowse link 16 20,120,753 20,122,702 RGD:1600115
G Insl6 insulin-like 6 JBrowse link 1 247,473,292 247,476,827 RGD:1600115
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:2290293
RGD:13792537
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:1600115
RGD:13792537
G LOC100912649 uncharacterized LOC100912649 RGD:1600115
G LOC103689989 prolactin-3D4 JBrowse link 17 42,920,993 42,927,704 RGD:1600115
RGD:13792537
G LOC103694085 prolactin-8A4 JBrowse link 17 39,601,828 39,607,728 RGD:1600115
G LOC684107 similar to placental prolactin-like protein O JBrowse link 17 38,919,078 38,928,447 RGD:13792537
G Metrn meteorin, glial cell differentiation regulator JBrowse link 10 15,164,439 15,166,457 RGD:13792537
G Metrnl meteorin-like, glial cell differentiation regulator JBrowse link 10 110,893,261 110,907,256 RGD:1624291
RGD:13792537
RGD:1600115
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:70434
RGD:13792537
RGD:1626243
RGD:1626242
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:1626243
RGD:13792537
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1580115
RGD:13792537
RGD:1601491
G Ostn osteocrin JBrowse link 11 76,851,923 76,888,140 RGD:1600115
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:1624291
RGD:1600115
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:625674
RGD:13792537
G Prl2a1 Prolactin family 2, subfamily a, member 1 JBrowse link 17 38,900,411 38,906,503 RGD:13792537
G Prl2b1 Prolactin family 2, subfamily b, member 1 JBrowse link 17 39,542,058 39,549,080 RGD:633805
RGD:13792537
RGD:1600115
G Prl2c1 Prolactin family 2, subfamily c, member 1 JBrowse link 17 38,849,932 38,858,391 RGD:13792537
G Prl3a1 Prolactin family 3, subfamily a, member 1 JBrowse link 17 42,723,745 42,740,021 RGD:13792537
G Prl3b1 Prolactin family 3, subfamily b, member 1 JBrowse link 17 42,771,523 42,777,186 RGD:13792537
G Prl3c1 Prolactin family 3, subfamily c, member 1 JBrowse link 17 42,812,517 42,818,305 RGD:633805
RGD:13792537
RGD:1600115
G Prl3d1 Prolactin family 3, subfamily d, member 1 JBrowse link 17 39,777,255 39,782,877 RGD:1600115
RGD:13792537
G Prl3d2 Prolactin family 3, subfamily d, member 2 JBrowse link 17 42,849,469 42,855,496 RGD:13792537
G Prl3d4 prolactin family 3, subfamily d, member 4 JBrowse link 17 39,271,883 39,278,716 RGD:13792537
G Prl4a1 prolactin family 4, subfamily a, member 1 JBrowse link 17 38,710,401 38,718,343 RGD:1600115
RGD:13792537
G Prl5a1 prolactin family 5, subfamily a, member 1 JBrowse link 17 38,323,633 38,331,051 RGD:633805
RGD:13792537
G Prl5a2 prolactin family 5, subfamily a, member 2 JBrowse link 17 38,456,016 38,462,358 RGD:13792537
G Prl6a1 prolactin family 6, subfamily a, member 1 JBrowse link 17 42,705,730 42,710,574 RGD:1600115
RGD:13792537
G Prl7a3 prolactin family 7, subfamily a, member 3 JBrowse link 17 39,032,661 39,045,326 RGD:1600115
RGD:13792537
G Prl7a4 prolactin family 7, subfamily a, member 4 JBrowse link 17 39,095,463 39,104,519 RGD:13792537
G Prl7b1 prolactin family 7, subfamily b, member 1 JBrowse link 17 39,153,431 39,161,644 RGD:1600115
RGD:13792537
G Prl7d1 prolactin family 7, subfamily d, member 1 JBrowse link 17 38,993,183 38,999,651 RGD:13792537
G Prl8a2 prolactin family 8, subfamily a, member 2 JBrowse link 17 39,563,383 39,575,777 RGD:13792537
G Prl8a3 prolactin family 8, subfamily a, member 3 JBrowse link 17 39,455,865 39,463,715 RGD:13792537
G Prl8a4 prolactin family 8, subfamily a, member 4 JBrowse link 17 39,376,040 39,382,128 RGD:1600115
RGD:13792537
G Prl8a5 prolactin family 8, subfamily a, member 5 JBrowse link 17 39,411,716 39,417,929 RGD:1600115
RGD:13792537
G Prl8a7 prolactin family 8, subfamily a, member 7 JBrowse link 17 39,509,516 39,515,418 RGD:1600115
RGD:13792537
G Prl8a9 prolactin family 8, subfamily a, member 9 JBrowse link 17 39,241,133 39,246,941 RGD:13792537
G Prlh prolactin releasing hormone JBrowse link 9 98,111,391 98,114,831 RGD:1299340
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:12793028
RGD:13792537
RGD:1624291
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:729903
RGD:13792537
G Pyy peptide YY (mapped) JBrowse link 10 90,047,989 90,049,155 RGD:1600115
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:1624972
G Retnla resistin like alpha JBrowse link 11 54,543,727 54,545,493 RGD:1600115
G Retnlb resistin like beta JBrowse link 11 54,565,471 54,567,578 RGD:1600115
G Retnlg resistin-like gamma JBrowse link 11 54,512,950 54,514,722 RGD:1600115
G Rln1 relaxin 1 JBrowse link 1 247,483,298 247,486,331 RGD:70239
G Rln3 relaxin 3 JBrowse link 19 25,164,497 25,166,528 RGD:1304438
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:14397557
G Smr3b submaxillary gland androgen regulated protein 3B JBrowse link 14 21,490,216 21,709,077 RGD:1600115
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:737697
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:1600115
G Stc2 stanniocalcin 2 JBrowse link 10 16,542,909 16,552,675 RGD:1600115
G Tg thyroglobulin JBrowse link 7 107,467,260 107,652,897 RGD:1600115
G Thpo thrombopoietin JBrowse link 11 82,845,676 82,853,439 RGD:1600115
G Thpol1 thrombopoietin like 1 JBrowse link 11 83,867,549 83,874,670 RGD:1600115
G Tor2a torsin family 2, member A JBrowse link 3 11,794,731 11,800,261 RGD:1600115
G Tshb thyroid stimulating hormone subunit beta JBrowse link 2 205,207,799 205,215,199 RGD:729979
RGD:13792537
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:1600115
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1600115
G Ucn2 urocortin 2 JBrowse link 8 117,727,216 117,728,765 RGD:1600115
G Ucn3 urocortin 3 JBrowse link 17 69,959,879 69,966,532 RGD:1600115
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:1600115
G Uts2b urotensin 2B JBrowse link 11 76,833,761 76,848,808 RGD:1600115
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:1624291
RGD:1600115
RGD:8554017
corticotropin-releasing hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:13792537
digestive hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:9590242
follicle-stimulating hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:1600115
RGD:13792537
RGD:1624291
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:61788
RGD:13792537
RGD:1624291
RGD:1600115
gonadotropin hormone-releasing hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:9685144
RGD:13792537
growth hormone-releasing hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:628502
RGD:13792537
RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624396
RGD:13792537
RGD:625505
melanin-concentrating hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pmch pro-melanin-concentrating hormone JBrowse link 7 28,655,206 28,656,522 RGD:1600115
neurohypophyseal hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:1600115
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:1600115
neuropeptide hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:8554519
RGD:13792537
RGD:1624291
G Agrp agouti related neuropeptide JBrowse link 19 37,525,941 37,584,875 RGD:1624291
RGD:1600115
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:2312653
RGD:13792537
RGD:1624291
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1600607
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:1600115
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:1626108
RGD:13792537
RGD:8553788
RGD:1624291
G Cort cortistatin JBrowse link 5 165,942,780 165,944,221 RGD:728223
RGD:13792537
RGD:1624291
G Ecrg4 ECRG4 augurin precursor JBrowse link 9 50,526,811 50,548,056 RGD:1624291
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:1624291
RGD:13792537
RGD:1600115
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:13792537
G Grp gastrin releasing peptide JBrowse link 18 61,563,458 61,576,818 RGD:1624291
RGD:1600115
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:628422
RGD:13792537
RGD:1600968
G LOC100912228 pro-neuropeptide Y-like JBrowse link 4 79,573,999 79,581,212 RGD:13792537
G NEWGENE_735020 pyroglutamylated RFamide peptide JBrowse link 3 10,035,024 10,036,981 RGD:1600115
RGD:13792537
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:633355
RGD:13792537
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1624291
RGD:1600115
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:13792537
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:1600115
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:1579892
RGD:13792537
RGD:2312653
G Ppy pancreatic polypeptide JBrowse link 10 90,041,582 90,043,316 RGD:13792537
G Prlh prolactin releasing hormone JBrowse link 9 98,111,391 98,114,831 RGD:1641829
G Pyy peptide YY (mapped) JBrowse link 10 90,047,989 90,049,155 RGD:1624395
RGD:13792537
RGD:1624291
G Qrfp pyroglutamylated RFamide peptide JBrowse link 3 9,402,397 9,404,354 RGD:1624291
RGD:13792537
RGD:1600115
G Spx spexin hormone JBrowse link 4 176,629,597 176,635,698 RGD:1600115
RGD:1624291
RGD:13792537
RGD:12907558
G Vgf VGF nerve growth factor inducible JBrowse link 12 22,677,302 22,680,630 RGD:1600115
RGD:1624291
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:13792537
pituitary adenylate cyclase activating polypeptide activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:1624291
RGD:13792537
RGD:1600115
RGD:8554017
thyrotropin-releasing hormone activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:634240
RGD:13792537

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  molecular_function 18471
    molecular function regulator 1722
      receptor regulator activity 495
        signaling receptor activator activity 460
          receptor ligand activity 454
            hormone activity 132
              corticotropin-releasing hormone activity 1
              digestive hormone activity 1
              diuretic hormone activity 0
              follicle-stimulating hormone activity 2
              gonadotropin hormone-releasing hormone activity 1
              growth hormone activity 0
              growth hormone-releasing hormone activity 2
              melanin-concentrating hormone activity 1
              melanocyte-stimulating hormone activity 0
              myoinhibitory hormone activity 0
              myostimulatory hormone activity 0
              neuropeptide hormone activity + 26
              pituitary adenylate cyclase activating polypeptide activity 1
              thyrotropin-releasing hormone activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.