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ONTOLOGY REPORT - ANNOTATIONS


Term:guanyl-nucleotide exchange factor activity
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Accession:GO:0005085 term browser browse the term
Definition:Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Comment:Note that guanyl-nucleotide exchange factor (GEF) activity alters binding affinity, but not GTPase catalytic activity directly. Therefore GO:0005085 is under 'regulation of GTPase activity' but is not a 'GTPase regulator', which is reserved for cases where the action of one gene product directly alters the rate of catalysis by another gene product.
Synonyms:exact_synonym: GDP-dissociation stimulator activity;   GDS;   GEF;   guanyl-nucleotide release factor activity;   guanyl-nucleotide releasing factor
 narrow_synonym: GNRP
 alt_id: GO:0008433;   GO:0016219;   GO:0019839
 xref: MIPS_funcat:18.02.03;   Reactome:R-HSA-442273 "VAV1 is a GEF for Rho/Rac family GTPases";   reactome:R-HSA-114544 "p115-RhoGEF activation of RHOA";   reactome:R-HSA-1168636 "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP";   reactome:R-HSA-1433415 "Activation of RAC1";   reactome:R-HSA-156913 "Regeneration of eEF1A:GTP by eEF1B activity";   reactome:R-HSA-169904 "C3G stimulates nucleotide exchange on Rap1";   reactome:R-HSA-170979 "(Frs2)C3G stimulates nucleotide exchange on Rap1";   reactome:R-HSA-187746 "RIT/RIN are activated";   reactome:R-HSA-2029445 "Activation of CDC42 by unknown mechanism";   reactome:R-HSA-2029451 "Activation of RAC1 by VAV";   reactome:R-HSA-2029467 "Activation of RAC1 by CRKII:DOCK180:ELMO";   reactome:R-HSA-203977 "SAR1 Activation And Membrane Binding";   reactome:R-HSA-205039 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor";   reactome:R-HSA-2424476 "Activation of RAC1 by VAV2/3";   reactome:R-HSA-2485180 "MII catalyses GDP/GTP exchange on Gt";   reactome:R-HSA-2730840 "Activation of RAC1 by VAV";   reactome:R-HSA-354173 "Activation of Rap1 by cytosolic GEFs";   reactome:R-HSA-379044 "Liganded Gs-activating GPCR acts as a GEF for Gs";   reactome:R-HSA-379048 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11";   reactome:R-HSA-380073 "Liganded Gi-activating GPCR acts as a GEF for Gi";   reactome:R-HSA-389348 "Activation of Rac1 by pVav1";   reactome:R-HSA-389350 "Activation of Cdc42 by pVav1";   reactome:R-HSA-392195 "Gi activation by P2Y purinoceptor 12";   reactome:R-HSA-3928592 "p190RhoGEF exchanges GTP for GDP on RHOA, activating it";   reactome:R-HSA-3928612 "KALRN exchanges GTP for GDP on RAC1, activating it";   reactome:R-HSA-3928628 "VAV exchanges GTP for GDP on RAC1, activating it";   reactome:R-HSA-3928632 "ITSN1 exchanges GTP for GDP on CDC42, activating it";   reactome:R-HSA-3928633 "bPIX exchanges GTP for GDP on RAC, activating it";   reactome:R-HSA-3928642 "TIAM1 exchanges GTP for GDP on RAC1, activating it";   reactome:R-HSA-3928651 "NGEF exchanges GTP for GDP on RHOA";   reactome:R-HSA-392870 "Gs activation by prostacyclin receptor";   reactome:R-HSA-3965444 "WNT:FZD complex promotes G-protein nucleotide exchange";   reactome:R-HSA-399995 "Muscarinic Acetylcholine Receptor M3 activates Gq";   reactome:R-HSA-4093336 "p-TIAM1 exchanges GTP for GDP on RAC1, activating it";   reactome:R-HSA-416530 "GPR40:fatty acid activates Gq";   reactome:R-HSA-418579 "Gq activation by P2Y purinoceptor 1";   reactome:R-HSA-420883 "Opsins act as GEFs for G alpha-t";   reactome:R-HSA-428750 "Gq activation by TP receptor";   reactome:R-HSA-428917 "G13 activation by TP receptor";   reactome:R-HSA-442291 "VAV2 is a GEF for Rho/Rac family kinases";   reactome:R-HSA-442314 "VAV3 is a GEF for Rho/Rac family kinases";   reactome:R-HSA-445064 "Activation of Rac1 by VAV2";   reactome:R-HSA-5218829 "VEGF induces CDC42 activation by unknown mechanism";   reactome:R-HSA-5218839 "DOCK180:ELMO exchanges GTP for GDP, activating RAC1";   reactome:R-HSA-5218850 "VAV exchanges GTP for GDP on RAC1, activating it";   reactome:R-HSA-5694409 "Nucleotide exchange on RAB1";   reactome:R-HSA-6807868 "GBF1 stimulates ARF nucleotide exchange";   reactome:R-HSA-6811429 "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange";   reactome:R-HSA-749453 "Liganded Gz-activating GPCR acts as a GEF for Gz";   reactome:R-HSA-751029 "Liganded G12/13-activating GPCR acts as a GEF for G12/13";   reactome:R-HSA-825631 "Glucagon:GCGR mediates GTP-GDP exchange";   reactome:R-HSA-8848618 "Activation of RAC1 by the PXN:CRK complex";   reactome:R-HSA-8850041 "RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18";   reactome:R-HSA-8851827 "RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1";   reactome:R-HSA-8851877 "RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET";   reactome:R-HSA-8851899 "RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET";   reactome:R-HSA-8875568 "RAPGEF1 activates RAP1";   reactome:R-HSA-8875591 "DOCK7 activates RAC1";   reactome:R-HSA-8964604 "CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated";   reactome:R-HSA-8982637 "Opsins binds G alpha-t";   reactome:R-HSA-8982640 "G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t)";   reactome:R-HSA-939265 "Activation of Rap1 by membrane-associated GEFs"


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guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07000581.1 RGD:1600115
G AABR07000583.1 RGD:1600115
G AABR07000595.1 RGD:1600115
G AABR07006688.2 RGD:13792537
G AABR07018646.1 RGD:1600115
G AABR07019903.1 RGD:1600115
G AABR07029272.1 RGD:1600115
G AABR07029605.1 RGD:1600115
G AABR07036505.1 RGD:1600115
G AABR07047293.1 RGD:1600115
G AABR07047606.1 RGD:1600115
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 JBrowse link 9 65,961,361 66,034,396 RGD:1624291
RGD:1600115
G Ankrd27 ankyrin repeat domain 27 JBrowse link 1 91,857,048 91,958,763 RGD:1624291
RGD:13792537
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 JBrowse link 5 8,666,046 8,760,458 RGD:1624291
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 JBrowse link 3 163,570,435 163,656,612 RGD:1304338
RGD:1624291
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link 16 79,725,629 79,817,065 RGD:13792537
G Arhgef17 Rho guanine nucleotide exchange factor 17 RGD:1624291
RGD:13792537
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 JBrowse link 12 1,889,252 1,998,128 RGD:1624291
G Arhgef19 Rho guanine nucleotide exchange factor 19 JBrowse link 5 159,754,954 159,773,699 RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1600115
G Arhgef26 Rho guanine nucleotide exchange factor 26 JBrowse link 2 27,107,263 27,236,336 RGD:1600115
G Arhgef28 Rho guanine nucleotide exchange factor 28 JBrowse link 2 25,738,514 26,011,429 RGD:1624291
G Arhgef3 Rho guanine nucleotide exchange factor 3 JBrowse link 16 2,743,714 3,026,768 RGD:1600115
G Arhgef33 Rho guanine nucleotide exchange factor 33 JBrowse link 6 2,982,324 3,100,358 RGD:1600115
G Arhgef37 Rho guanine nucleotide exchange factor 37 JBrowse link 18 56,817,986 56,871,159 RGD:1600115
G Arhgef39 Rho guanine nucleotide exchange factor 39 JBrowse link 5 58,998,209 59,001,779 RGD:1600115
G Arhgef4 Rho guanine nucleotide exchange factor 4 JBrowse link 9 41,160,562 41,305,015 RGD:1624291
G Arhgef40 Rho guanine nucleotide exchange factor 40 JBrowse link 15 28,377,916 28,403,090 RGD:1600115
G Arhgef5 Rho guanine nucleotide exchange factor 5 JBrowse link 4 72,710,775 72,736,415 RGD:1624291
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 JBrowse link X 159,722,031 159,841,344 RGD:1600115
G Arhgef7 Rho guanine nucleotide exchange factor 7 JBrowse link 16 83,006,732 83,117,065 RGD:633693
RGD:1600115
RGD:1624291
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 JBrowse link X 64,249,576 64,428,444 RGD:1600115
G Bcar3 BCAR3 adaptor protein, NSP family member JBrowse link 2 226,563,050 226,679,449 RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
G Ccdc88c coiled-coil domain containing 88C JBrowse link 6 124,905,811 125,028,011 RGD:1624291
G Ccz1b CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated JBrowse link 12 12,638,849 12,662,371 RGD:1624291
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:625569
G Dennd10 DENN domain containing 10 JBrowse link 1 282,188,080 282,211,588 RGD:1624291
RGD:1600115
G Dennd11 DENN domain containing 11 JBrowse link 4 68,569,308 68,597,626 RGD:1600115
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease JBrowse link 15 83,466,330 83,494,107 RGD:1624291
RGD:1600115
G Dock1 dedicator of cyto-kinesis 1 JBrowse link 1 206,900,617 207,414,852 RGD:1624291
RGD:1600115
G Dock10 dedicator of cytokinesis 10 JBrowse link 9
9
86,424,638
86,312,470
86,571,854
86,423,054
RGD:1624291
G Dock11 dedicator of cytokinesis 11 JBrowse link X 122,507,169 122,690,463 RGD:1624291
RGD:1600115
G Dock3 dedicator of cyto-kinesis 3 JBrowse link 8 115,627,282 115,982,260 RGD:1600115
G Dock4 dedicator of cytokinesis 4 JBrowse link 6 60,374,839 60,782,648 RGD:1600115
G Dock5 dedicator of cytokinesis 5 JBrowse link 15 44,449,108 44,627,774 RGD:1624291
RGD:1600115
G Dock6 dedicator of cytokinesis 6 JBrowse link 8 22,822,412 22,874,670 RGD:1600115
G Dock7 dedicator of cytokinesis 7 JBrowse link 5 117,595,194 117,780,844 RGD:1600115
G Dock8 dedicator of cytokinesis 8 JBrowse link 1 242,934,685 243,153,472 RGD:1624291
RGD:1600115
G Dock9 dedicator of cytokinesis 9 JBrowse link 15 107,945,664 108,210,967 RGD:1600115
RGD:1624291
G Ect2 epithelial cell transforming 2 JBrowse link 2 112,769,385 112,831,476 RGD:1600115
G Ect2l epithelial cell transforming 2 like JBrowse link 1 13,301,918 13,372,928 RGD:1600115
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 JBrowse link 9 69,953,440 69,956,158 RGD:13792537
G Eef1d eukaryotic translation elongation factor 1 delta JBrowse link 7 116,928,264 116,942,981 RGD:13792537
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link 12 37,444,136 37,452,391 RGD:1581073
RGD:13792537
RGD:1600115
RGD:1624291
RGD:11041878
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 6 109,044,830 109,051,254 RGD:8553751
RGD:13792537
RGD:1624291
RGD:1600115
RGD:1581075
RGD:11041878
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link 5 135,882,946 135,949,276 RGD:1581073
RGD:1624291
RGD:1600115
RGD:11041878
RGD:8553751
RGD:1581077
RGD:1581075
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 6 26,546,917 26,552,474 RGD:1581073
RGD:1624291
RGD:1600115
RGD:11041878
RGD:8553751
RGD:1581075
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:1581073
RGD:13792537
RGD:1600115
RGD:1624291
RGD:11041878
RGD:8553751
RGD:1581085
RGD:1581075
G Elmo1 engulfment and cell motility 1 JBrowse link 17 46,352,102 46,888,788 RGD:1624291
RGD:1600115
G Fgd1 FYVE, RhoGEF and PH domain containing 1 JBrowse link X 20,100,942 20,143,871 RGD:1624291
G Fgd3 FYVE, RhoGEF and PH domain containing 3 JBrowse link 17 15,737,962 15,800,403 RGD:1600115
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 11 88,699,222 88,796,677 RGD:1600115
G Fgd5 FYVE, RhoGEF and PH domain containing 5 JBrowse link 4 123,865,557 123,962,904 RGD:1600115
G Fgd6 FYVE, RhoGEF and PH domain containing 6 JBrowse link 7 34,951,878 35,063,006 RGD:1600115
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1600115
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Gapvd1 GTPase activating protein and VPS9 domains 1 JBrowse link 3 13,751,572 13,825,573 RGD:1624291
RGD:1600115
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 JBrowse link 1 261,989,178 262,015,282 RGD:1624291
RGD:1600115
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 JBrowse link 12 50,285,239 50,315,893 RGD:1624291
RGD:1600115
G Itsn1 intersectin 1 JBrowse link 11 31,943,119 32,069,249 RGD:1600115
G Itsn2 intersectin 2 JBrowse link 6 30,098,378 30,208,694 RGD:1600115
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:628431
RGD:1624291
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 1 166,991,474 166,997,045 RGD:1624291
RGD:13792537
RGD:1600115
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 2 187,911,530 187,914,930 RGD:1624291
RGD:13792537
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 2 243,160,821 243,173,057 RGD:1624291
RGD:1600115
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 12 19,573,909 19,577,625 RGD:1624291
RGD:13792537
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:1624291
RGD:13792537
G LOC100361543 RhoA activator C11orf59-like JBrowse link X 37,261,428 37,262,470 RGD:1600115
RGD:13792537
G LOC100911649 ral guanine nucleotide dissociation stimulator-like JBrowse link 16 12,739,773 12,742,080 RGD:1600115
G LOC102552619 uncharacterized LOC102552619 JBrowse link 10 41,489,533 41,491,613 RGD:1600115
G LOC102552882 uncharacterized LOC102552882 JBrowse link 10 41,544,660 41,835,362 RGD:1600115
G LOC685463 similar to Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS) JBrowse link 16 12,736,364 12,738,310 RGD:1600115
G Mcf2 MCF.2 cell line derived transforming sequence JBrowse link X 143,159,071 143,292,467 RGD:1624291
G Mcf2l MCF.2 cell line derived transforming sequence-like JBrowse link 16 81,839,686 81,986,007 RGD:1600115
G Mon1a MON1 homolog A, secretory trafficking associated JBrowse link 8 116,657,345 116,682,172 RGD:1624291
RGD:1600115
G Mycbp2 MYC binding protein 2 JBrowse link 15
15
87,405,472
93,678,062
87,450,812
93,901,556
RGD:1600115
RGD:1624291
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:1600115
G Ngef neuronal guanine nucleotide exchange factor JBrowse link 9 94,569,286 94,601,852 RGD:1624291
RGD:1600115
G Nucb1 nucleobindin 1 JBrowse link 1 101,480,160 101,511,029 RGD:14929204
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:14929204
G Pcp2 Purkinje cell protein 2 JBrowse link 12 2,172,378 2,174,674 RGD:1624291
RGD:13792537
G Plcd4 phospholipase C, delta 4 JBrowse link 9 81,816,395 81,844,364 RGD:1624291
G Plce1 phospholipase C, epsilon 1 JBrowse link 1 257,156,023 257,465,440 RGD:1600115
G Plekhg1 pleckstrin homology and RhoGEF domain containing G1 JBrowse link 1 40,286,908 40,521,395 RGD:1600115
G Plekhg2 pleckstrin homology and RhoGEF domain containing G2 JBrowse link 1 85,386,492 85,399,699 RGD:1600115
G Plekhg3 pleckstrin homology and RhoGEF domain containing G3 JBrowse link 6 99,612,993 99,655,753 RGD:1600115
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 JBrowse link 19 37,327,395 37,345,047 RGD:1600115
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 JBrowse link 5 169,244,778 169,288,310 RGD:1600115
G Plekhg6 pleckstrin homology and RhoGEF domain containing G6 JBrowse link 4 157,877,725 157,897,167 RGD:1600115
G Rab3ip RAB3A interacting protein JBrowse link 7 59,927,486 59,971,518 RGD:1600115
G Rabif RAB interacting factor JBrowse link 13 51,317,476 51,330,536 RGD:13792537
G Ralgds ral guanine nucleotide dissociation stimulator JBrowse link 3 7,090,134 7,130,548 RGD:1600115
G Ralgps2 Ral GEF with PH domain and SH3 binding motif 2 JBrowse link 13 74,446,001 74,520,640 RGD:1600115
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:1624291
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:1624291
RGD:1600115
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:632397
RGD:1624291
G Rapgef5 Rap guanine nucleotide exchange factor 5 JBrowse link 6 145,387,890 145,625,243 RGD:1600115
G Rapgef6 Rap guanine nucleotide exchange factor 6 JBrowse link 10 39,875,322 40,039,929 RGD:1624291
RGD:1600115
G Rapgefl1 Rap guanine nucleotide exchange factor like 1 JBrowse link 10 86,749,220 86,765,677 RGD:1600115
G Rasgef1c RasGEF domain family, member 1C JBrowse link 10 35,392,762 35,459,267 RGD:1600115
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1600115
G Rasgrp2 RAS guanyl releasing protein 2 JBrowse link 1 221,771,238 221,788,765 RGD:1600115
RGD:1624291
G Rasgrp3 RAS guanyl releasing protein 3 JBrowse link 6 21,072,634 21,171,619 RGD:1600115
G Rcc1l RCC1 like JBrowse link 12 25,561,871 25,592,337 RGD:1600115
RGD:1624291
G RGD1359108 similar to RIKEN cDNA 3110043O21 JBrowse link 5 50,666,444 50,691,523 RGD:1600115
G RGD1559508 similar to hypothetical protein 4930474N05 JBrowse link 16 12,659,206 12,663,594 RGD:1600115
G RGD1561114 similar to hypothetical protein 4930474N05 JBrowse link 18 41,896,720 41,899,400 RGD:1600115
G RGD1562508 similar to hypothetical protein 4930474N05 JBrowse link 16 12,701,049 12,704,441 RGD:1600115
G RGD1563962 similar to Mss4 protein JBrowse link 2 165,805,230 165,816,725 RGD:13792537
G RGD1564129 similar to hypothetical protein 4930474N05 JBrowse link 17 56,935,121 56,937,957 RGD:1600115
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 JBrowse link 20 5,458,509 5,466,853 RGD:1600115
G Ric8a RIC8 guanine nucleotide exchange factor A JBrowse link 1 213,606,599 213,612,905 RGD:633903
RGD:13792537
RGD:8553612
G Ric8b RIC8 guanine nucleotide exchange factor B JBrowse link 7 25,919,266 26,015,506 RGD:13792537
G Rinl Ras and Rab interactor-like JBrowse link 1 86,971,997 86,983,306 RGD:1624291
RGD:1600115
G Sh2d3c SH2 domain containing 3C JBrowse link 3 11,756,427 11,793,547 RGD:1600115
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:1624291
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:1624291
G Spata13 spermatogenesis associated 13 JBrowse link 15 40,937,652 41,066,645 RGD:1624291
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:1624291
G Tiam2 TIAM Rac1 associated GEF 2 JBrowse link 1 44,232,520 44,433,450 RGD:1624291
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:727273
RGD:1624291
G Vav2 vav guanine nucleotide exchange factor 2 JBrowse link 3 5,811,504 5,976,311 RGD:1624291
G Vav3 vav guanine nucleotide exchange factor 3 JBrowse link 2 212,247,061 212,585,818 RGD:1624291
ARF guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 JBrowse link 5 8,666,046 8,760,458 RGD:1600115
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 JBrowse link 3 163,570,435 163,656,612 RGD:1624291
RGD:1600115
G Arfgef3 ARFGEF family member 3 JBrowse link 1 13,837,861 13,918,277 RGD:1600115
G Cyth1 cytohesin 1 JBrowse link 10 107,197,983 107,281,285 RGD:1624291
RGD:1600115
G Cyth2 cytohesin 2 JBrowse link 1 101,796,349 101,803,407 RGD:1600115
RGD:1624291
G Cyth3 cytohesin 3 JBrowse link 12 12,877,559 12,907,771 RGD:1600115
RGD:1624291
G Cyth4 cytohesin 4 JBrowse link 7 119,820,521 119,845,003 RGD:1624291
RGD:1600115
G Fbxo8 F-box protein 8 JBrowse link 16 37,131,566 37,177,033 RGD:1600115
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 JBrowse link 1 265,904,616 266,033,107 RGD:1600115
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 JBrowse link 4 123,400,717 123,454,656 RGD:1600115
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 JBrowse link X 22,212,137 22,293,810 RGD:1624291
RGD:1600115
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 JBrowse link 4 153,948,052 154,044,493 RGD:1600115
G Preb prolactin regulatory element binding JBrowse link 6 26,784,088 26,787,875 RGD:1624291
G Psd pleckstrin and Sec7 domain containing JBrowse link 1 266,059,331 266,074,774 RGD:1624291
RGD:1600115
G Psd2 pleckstrin and Sec7 domain containing 2 JBrowse link 18 28,781,267 28,832,429 RGD:1600115
G Psd3 pleckstrin and Sec7 domain containing 3 JBrowse link 16 23,212,165 23,789,414 RGD:1624291
RGD:13792537
G Psd4 pleckstrin and Sec7 domain containing 4 JBrowse link 3 1,478,432 1,515,094 RGD:1600115
G Sec61b Sec61 translocon beta subunit JBrowse link 5 63,192,322 63,200,532 RGD:13792537
Rab guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 JBrowse link 9 65,961,361 66,034,396 RGD:1624291
RGD:1600115
G Als2cl ALS2 C-terminal like JBrowse link 8 119,156,081 119,176,680 RGD:1624291
G Dennd1a DENN domain containing 1A JBrowse link 3 22,061,120 22,501,502 RGD:1624291
RGD:13792537
G Dennd1b DENN domain containing 1B JBrowse link 13 56,015,813 56,242,041 RGD:1624291
RGD:13792537
G Dennd1c DENN domain containing 1C JBrowse link 9 9,976,015 9,982,349 RGD:1624291
RGD:13792537
G Dennd2a DENN domain containing 2A JBrowse link 4 67,242,257 67,342,993 RGD:1624291
RGD:1600115
G Dennd2b DENN domain containing 2B JBrowse link 1 174,137,120 174,290,533 RGD:1624291
RGD:1600115
G Dennd2c DENN domain containing 2C JBrowse link 2 205,592,348 205,660,619 RGD:1624291
RGD:1600115
G Dennd2d DENN domain containing 2D JBrowse link 2 209,097,894 209,116,978 RGD:1624291
RGD:1600115
G Dennd3 DENN domain containing 3 JBrowse link 7 114,724,644 114,812,471 RGD:1624291
RGD:1600115
G Dennd4a DENN domain containing 4A JBrowse link 8 70,293,355 70,406,675 RGD:1624291
RGD:1600115
G Dennd4b DENN domain containing 4B JBrowse link 2 189,626,922 189,642,732 RGD:1624291
RGD:1600115
G Dennd4c DENN domain containing 4C JBrowse link 5 105,100,081 105,195,634 RGD:1624291
RGD:1600115
G Dennd5a DENN domain containing 5A JBrowse link 1 174,524,047 174,588,553 RGD:1624291
RGD:1600115
G Dennd5b DENN domain containing 5B JBrowse link 4 183,476,093 183,604,940 RGD:1624291
G Dennd6a DENN domain containing 6A JBrowse link 16 2,278,701 2,327,062 RGD:1624291
RGD:13792537
G Dennd6b DENN domain containing 6B JBrowse link 7 130,162,728 130,178,282 RGD:1624291
RGD:13792537
G Madd MAP-kinase activating death domain JBrowse link 3 79,960,301 80,003,023 RGD:9588648
RGD:13792537
RGD:1624291
RGD:1600115
G Preb prolactin regulatory element binding JBrowse link 6 26,784,088 26,787,875 RGD:1624291
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1600115
RGD:1624291
G Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2 JBrowse link 13 103,157,806 103,229,010 RGD:1600115
RGD:13792537
RGD:1624291
G Rab3il1 RAB3A interacting protein-like 1 JBrowse link 1 226,077,182 226,084,830 RGD:632896
RGD:1624291
RGD:1600115
G Rab3ip RAB3A interacting protein JBrowse link 7 59,927,486 59,971,518 RGD:11534981
RGD:1600115
RGD:1624291
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
G RGD1359108 similar to RIKEN cDNA 3110043O21 JBrowse link 5 50,666,444 50,691,523 RGD:1600115
RGD:1624291
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 JBrowse link 5 59,080,290 59,088,777 RGD:1624291
RGD:13792537
G Ric1 RIC1 homolog, RAB6A GEF complex partner 1 JBrowse link 1 247,688,778 247,784,219 RGD:1624291
RGD:13792537
G Rin3 Ras and Rab interactor 3 JBrowse link 6 126,170,672 126,279,682 RGD:1624291
RGD:1600115
G Sbf1 SET binding factor 1 JBrowse link 7 130,261,552 130,288,566 RGD:1624291
RGD:1600115
G Sbf2 SET binding factor 2 JBrowse link 1 174,948,361 175,420,161 RGD:1624291
RGD:1600115
G Sh3bp5 SH3-domain binding protein 5 JBrowse link 16 7,473,367 7,559,976 RGD:1600115
RGD:1624291
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link 10 43,768,620 43,785,702 RGD:1600115
RGD:1624291
G Smcr8 SMCR8-C9orf72 complex subunit JBrowse link 10 47,019,326 47,026,465 RGD:1624291
RGD:13792537
G Trappc1 trafficking protein particle complex 1 JBrowse link 10 55,924,996 55,926,582 RGD:13792537
G Trappc3 trafficking protein particle complex 3 JBrowse link 5 144,281,720 144,295,306 RGD:13792537
G Trappc3l trafficking protein particle complex 3-like JBrowse link 20 27,578,268 27,664,689 RGD:13792537
G Trappc4 trafficking protein particle complex 4 JBrowse link 8 48,723,755 48,727,182 RGD:13792537
G Trappc5 trafficking protein particle complex 5 JBrowse link 12 2,228,670 2,232,973 RGD:13792537
G Wdr41 WD repeat domain 41 JBrowse link 2 24,668,108 24,717,280 RGD:1624291
RGD:1600115
Rac guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 JBrowse link 9 65,961,361 66,034,396 RGD:1624291
RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
RGD:1600115
G Arhgef4 Rho guanine nucleotide exchange factor 4 JBrowse link 9 41,160,562 41,305,015 RGD:1624291
RGD:1600115
G Dock2 dedicator of cytokinesis 2 JBrowse link 10 19,181,512 19,603,171 RGD:1624291
G Eps8 epidermal growth factor receptor pathway substrate 8 JBrowse link 4 171,475,155 171,645,620 RGD:13792537
G Eps8l1 EPS8-like 1 JBrowse link 1 72,926,106 72,942,433 RGD:1624291
RGD:13792537
G Eps8l2 EPS8-like 2 JBrowse link 1 214,327,992 214,353,466 RGD:1624291
RGD:13792537
G Eps8l3 EPS8 like 3 JBrowse link 2 210,668,249 210,681,930 RGD:1624291
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 JBrowse link 15 106,375,298 106,625,837 RGD:8554251
RGD:13792537
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 JBrowse link 9 100,660,366 100,767,940 RGD:1624291
RGD:13792537
G Frmd7 FERM domain containing 7 JBrowse link X 138,095,707 138,149,702 RGD:13792537
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1624291
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 JBrowse link 3 163,329,580 163,477,822 RGD:13792537
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 JBrowse link 5 7,622,668 7,941,715 RGD:1624291
RGD:13792537
G Spata13 spermatogenesis associated 13 JBrowse link 15 40,937,652 41,066,645 RGD:1624291
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:1624291
RGD:1600115
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:1624291
RGD:1600115
G Vav3 vav guanine nucleotide exchange factor 3 JBrowse link 2 212,247,061 212,585,818 RGD:1624291
RGD:1600115
Ral guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ralgds ral guanine nucleotide dissociation stimulator JBrowse link 3 7,090,134 7,130,548 RGD:69953
RGD:1600115
G Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 JBrowse link 3 12,182,722 12,415,081 RGD:1624291
RGD:1600115
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 JBrowse link 13 69,909,122 70,174,590 RGD:1600115
G Rgl3 ral guanine nucleotide dissociation stimulator-like 3 JBrowse link 8 22,980,727 23,000,881 RGD:1624291
RGD:1600115
Ran guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ranbp10 RAN binding protein 10 JBrowse link 19 37,734,662 37,795,360 RGD:1624291
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1600115
G Rcc1 regulator of chromosome condensation 1 JBrowse link 5 150,508,840 150,531,062 RGD:1624291
RGD:1600115
Rap guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:8554481
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:1624291
RGD:1600115
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:8554481
RGD:1624291
RGD:1600115
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:1624291
RGD:1600115
G Rapgef5 Rap guanine nucleotide exchange factor 5 JBrowse link 6 145,387,890 145,625,243 RGD:1624291
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:633848
Ras guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007642.1 RGD:1600115
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:1600115
RGD:1624291
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Kndc1 kinase non-catalytic C-lobe domain containing 1 JBrowse link 1 212,229,751 212,279,254 RGD:1624291
RGD:13792537
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:1600115
RGD:1624291
G Rasgef1a RasGEF domain family, member 1A JBrowse link 4 150,063,484 150,144,203 RGD:1624291
RGD:1600115
G Rasgef1b RasGEF domain family, member 1B JBrowse link 14 11,499,692 12,028,513 RGD:1624291
RGD:1600115
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1624291
RGD:1600115
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:1624291
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G Rasgrp3 RAS guanyl releasing protein 3 JBrowse link 6 21,072,634 21,171,619 RGD:1624291
RGD:1600115
G Rasgrp4 RAS guanyl releasing protein 4 JBrowse link 1 88,078,350 88,094,331 RGD:1600115
RGD:1624291
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:1624291
RGD:1600115
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:1624291
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:1624291
Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1600115
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1624291
RGD:1600115
G Arhgef1 Rho guanine nucleotide exchange factor 1 JBrowse link 1 81,769,212 81,797,237 RGD:1600115
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link 16 79,725,629 79,817,065 RGD:1624291
RGD:13792537
G Arhgef10l Rho guanine nucleotide exchange factor 10 like JBrowse link 5 159,018,373 159,089,383 RGD:1600115
G Arhgef11 Rho guanine nucleotide exchange factor 11 JBrowse link 2 186,979,850 187,102,523 RGD:1600115
G Arhgef12 Rho guanine nucleotide exchange factor 12 JBrowse link 8 47,259,377 47,393,042 RGD:1600115
G Arhgef15 Rho guanine nucleotide exchange factor 15 JBrowse link 10 55,532,097 55,545,675 RGD:8554375
RGD:1600115
RGD:1624291
G Arhgef16 Rho guanine nucleotide exchange factor 16 JBrowse link 5 171,626,450 171,649,124 RGD:1624291
RGD:1600115
G Arhgef17 Rho guanine nucleotide exchange factor 17 RGD:13792537
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 JBrowse link 12 1,889,252 1,998,128 RGD:1600115
G Arhgef19 Rho guanine nucleotide exchange factor 19 JBrowse link 5 159,754,954 159,773,699 RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
RGD:1600115
G Arhgef25 Rho guanine nucleotide exchange factor 25 JBrowse link 7 70,469,304 70,476,633 RGD:1600115
G Arhgef26 Rho guanine nucleotide exchange factor 26 JBrowse link 2 27,107,263 27,236,336 RGD:1600115
G Arhgef28 Rho guanine nucleotide exchange factor 28 JBrowse link 2 25,738,514 26,011,429 RGD:1600115
G Arhgef3 Rho guanine nucleotide exchange factor 3 JBrowse link 16 2,743,714 3,026,768 RGD:1600115
G Arhgef33 Rho guanine nucleotide exchange factor 33 JBrowse link 6 2,982,324 3,100,358 RGD:1600115
G Arhgef37 Rho guanine nucleotide exchange factor 37 JBrowse link 18 56,817,986 56,871,159 RGD:1600115
RGD:13792537
G Arhgef39 Rho guanine nucleotide exchange factor 39 JBrowse link 5 58,998,209 59,001,779 RGD:1600115
G Arhgef40 Rho guanine nucleotide exchange factor 40 JBrowse link 15 28,377,916 28,403,090 RGD:1600115
G Arhgef5 Rho guanine nucleotide exchange factor 5 JBrowse link 4 72,710,775 72,736,415 RGD:1600115
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 JBrowse link X 159,722,031 159,841,344 RGD:1600115
G Arhgef7 Rho guanine nucleotide exchange factor 7 JBrowse link 16 83,006,732 83,117,065 RGD:1600115
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 JBrowse link X 64,249,576 64,428,444 RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
RGD:1600115
G Dnmbp dynamin binding protein JBrowse link 1 263,625,503 263,718,784 RGD:13792537
RGD:1624291
RGD:1600115
G Dock10 dedicator of cytokinesis 10 JBrowse link 9
9
86,424,638
86,312,470
86,571,854
86,423,054
RGD:1624291
G Dock11 dedicator of cytokinesis 11 JBrowse link X 122,507,169 122,690,463 RGD:1624291
RGD:1600115
G Dock9 dedicator of cytokinesis 9 JBrowse link 15 107,945,664 108,210,967 RGD:1624291
G Ect2 epithelial cell transforming 2 JBrowse link 2 112,769,385 112,831,476 RGD:1600115
RGD:1624291
G Ect2l epithelial cell transforming 2 like JBrowse link 1 13,301,918 13,372,928 RGD:1600115
G Eps8l1 EPS8-like 1 JBrowse link 1 72,926,106 72,942,433 RGD:1624291
G Eps8l2 EPS8-like 2 JBrowse link 1 214,327,992 214,353,466 RGD:1624291
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 JBrowse link 9 100,660,366 100,767,940 RGD:1624291
G Fgd2 FYVE, RhoGEF and PH domain containing 2 JBrowse link 20 6,973,356 6,990,026 RGD:1624291
RGD:1600115
G Fgd3 FYVE, RhoGEF and PH domain containing 3 JBrowse link 17 15,737,962 15,800,403 RGD:1600115
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 11 88,699,222 88,796,677 RGD:1600115
G Fgd5 FYVE, RhoGEF and PH domain containing 5 JBrowse link 4 123,865,557 123,962,904 RGD:1600115
G Fgd6 FYVE, RhoGEF and PH domain containing 6 JBrowse link 7 34,951,878 35,063,006 RGD:1600115
G Itsn1 intersectin 1 JBrowse link 11 31,943,119 32,069,249 RGD:1600115
G Itsn2 intersectin 2 JBrowse link 6 30,098,378 30,208,694 RGD:1600115
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1600115
G LOC102556447 rho guanine nucleotide exchange factor 38-like JBrowse link 2 238,376,034 238,468,652 RGD:13792537
G Mcf2 MCF.2 cell line derived transforming sequence JBrowse link X 143,159,071 143,292,467 RGD:1600115
G Mcf2l MCF.2 cell line derived transforming sequence-like JBrowse link 16 81,839,686 81,986,007 RGD:1600115
RGD:1624291
RGD:729022
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:1600115
G Ngef neuronal guanine nucleotide exchange factor JBrowse link 9 94,569,286 94,601,852 RGD:1600115
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 10 45,353,185 45,483,570 RGD:633514
G Plekhg1 pleckstrin homology and RhoGEF domain containing G1 JBrowse link 1 40,286,908 40,521,395 RGD:1600115
G Plekhg2 pleckstrin homology and RhoGEF domain containing G2 JBrowse link 1 85,386,492 85,399,699 RGD:1600115
G Plekhg3 pleckstrin homology and RhoGEF domain containing G3 JBrowse link 6 99,612,993 99,655,753 RGD:1600115
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 JBrowse link 19 37,327,395 37,345,047 RGD:1600115
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 JBrowse link 5 169,244,778 169,288,310 RGD:1624291
RGD:1600115
G Plekhg6 pleckstrin homology and RhoGEF domain containing G6 JBrowse link 4 157,877,725 157,897,167 RGD:1600115
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1600115
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:1600115
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 JBrowse link 20 5,458,509 5,466,853 RGD:1624291
RGD:1600115
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:1600115
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:1600115
G Spata13 spermatogenesis associated 13 JBrowse link 15 40,937,652 41,066,645 RGD:1600115
G Tiam2 TIAM Rac1 associated GEF 2 JBrowse link 1 44,232,520 44,433,450 RGD:1600115
G Trio trio Rho guanine nucleotide exchange factor JBrowse link 2 80,471,398 80,769,313 RGD:1600115
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:1624291
RGD:1600115
G Vav2 vav guanine nucleotide exchange factor 2 JBrowse link 3 5,811,504 5,976,311 RGD:1600115
G Vav3 vav guanine nucleotide exchange factor 3 JBrowse link 2 212,247,061 212,585,818 RGD:1624291
RGD:1600115
Sar guanyl-nucleotide exchange factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Preb prolactin regulatory element binding JBrowse link 6 26,784,088 26,787,875 RGD:1600115
RGD:13792537
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19460
    molecular function regulator 1759
      guanyl-nucleotide exchange factor activity 226
        ARF guanyl-nucleotide exchange factor activity 18
        Ras guanyl-nucleotide exchange factor activity + 136
        Sar guanyl-nucleotide exchange factor activity 1
        cAMP-dependent guanyl-nucleotide exchange factor activity 0
Path 2
Term Annotations click to browse term
  molecular_function 19460
    binding 15841
      protein binding 12616
        enzyme binding 2384
          GTPase binding 548
            guanyl-nucleotide exchange factor activity 226
              ARF guanyl-nucleotide exchange factor activity 18
              Ras guanyl-nucleotide exchange factor activity + 136
              Sar guanyl-nucleotide exchange factor activity 1
              cAMP-dependent guanyl-nucleotide exchange factor activity 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.