ONTOLOGY REPORT - ANNOTATIONS
Term: guanyl-nucleotide exchange factor activity
Accession: GO:0005085
Definition: Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
Synonyms: exact_synonym: GDP-dissociation stimulator activity; GDS; GEF; Rho guanine nucleotide exchange factor; RhoGEF; guanyl-nucleotide release factor activity; guanyl-nucleotide releasing factor narrow_synonym: ARF guanyl-nucleotide exchange factor activity; GNRP; Rab guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; Ral guanyl-nucleotide exchange factor activity; Ran guanyl-nucleotide exchange factor activity; Rap guanyl-nucleotide exchange factor activity; Ras guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; Sar guanyl-nucleotide exchange factor activity; cAMP-dependent guanyl-nucleotide exchange factor activity alt_id: GO:0005086; GO:0005087; GO:0005088; GO:0005089; GO:0005090; GO:0008321; GO:0008433; GO:0016219; GO:0016220; GO:0017034; GO:0017112; GO:0017132; GO:0019839; GO:0030676 xref: Reactome:R-HSA-109807 "GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS"; Reactome:R-HSA-109817 "GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS"; Reactome:R-HSA-1225951 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)"; Reactome:R-HSA-1225957 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants)"; Reactome:R-HSA-1250383 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4"; Reactome:R-HSA-1250463 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers"; Reactome:R-HSA-1250498 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers."; Reactome:R-HSA-1306972 "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers"; Reactome:R-HSA-1433471 "Activation of RAS by p-KIT bound SOS1"; Reactome:R-HSA-171026 "Guanine nucleotide exchange on RAL"; Reactome:R-HSA-177938 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)"; Reactome:R-HSA-177945 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)"; Reactome:R-HSA-180687 "Conversion of Ran-GDP to Ran-GTP"; Reactome:R-HSA-186834 "SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS)"; Reactome:R-HSA-194518 "RhoA is activated by nucleotide exchange and inhibits axonal growth"; Reactome:R-HSA-2029445 "An unknown GEF exchanges GTP for GDP on CDC42:GDP"; Reactome:R-HSA-210977 "Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos)"; Reactome:R-HSA-2179407 "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)"; Reactome:R-HSA-2424477 "SOS mediated nucleotide exchange of RAS (SHC)"; Reactome:R-HSA-350769 "trans-Golgi Network Coat Activation"; Reactome:R-HSA-392054 "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras"; Reactome:R-HSA-399938 "Activation of Rac1 by FARP2"; Reactome:R-HSA-400092 "Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins"; Reactome:R-HSA-416530 "FFAR1:FFAR1 ligands activate Gq"; Reactome:R-HSA-416588 "Activation of Rho by LARG and PDZ-RhoGEF"; Reactome:R-HSA-418850 "Activation of Cdc42"; Reactome:R-HSA-418856 "Activation of Rac1"; Reactome:R-HSA-419166 "GEFs activate RhoA,B,C"; Reactome:R-HSA-428535 "Activation of RAC1 by SOS"; Reactome:R-HSA-442273 "VAV1 is a GEF for Rho/Rac family GTPases"; Reactome:R-HSA-442732 "NMDA-activated RASGRF1 activates RAS"; Reactome:R-HSA-5617816 "RAB3IP stimulates nucleotide exchange on RAB8A"; Reactome:R-HSA-5623508 "GBF1 stimulates nucleotide exchange on ARF4"; Reactome:R-HSA-5623521 "RAB3IP stimulates nucleotide exchange on RAB8A"; Reactome:R-HSA-5637806 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII)"; Reactome:R-HSA-5637808 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII)"; Reactome:R-HSA-5654392 "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654402 "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654413 "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654426 "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654600 "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654618 "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654647 "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5654663 "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5655241 "Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5655277 "Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5655326 "Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5655347 "Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange"; Reactome:R-HSA-5672965 "RAS GEFs promote RAS nucleotide exchange"; Reactome:R-HSA-5686071 "GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS"; Reactome:R-HSA-5686318 "GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS"; Reactome:R-HSA-6811414 "GBF1 stimulates nucleotide exchange on ARF"; Reactome:R-HSA-6811418 "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane"; Reactome:R-HSA-8875318 "RAB3 GEFs exchange GTP for GDP on RAB3A"; Reactome:R-HSA-8875320 "RAB5 GEFs exchange GTP for GDP on RAB5"; Reactome:R-HSA-8876188 "DENND4s exchange GTP for GDP on RAB10"; Reactome:R-HSA-8876190 "RAB8 GEFs exchange GTP for GDP on RAB8"; Reactome:R-HSA-8876191 "RAB9 GEFs exchange GTP for GDP on RAB9"; Reactome:R-HSA-8876193 "RIC1-RGP1 exchanges GTP for GDP on RAB6"; Reactome:R-HSA-8876454 "DENND3 exchanges GTP for GDP on RAB12"; Reactome:R-HSA-8876615 "RAB13 GEFs exchange GTP for GDP on RAB13"; Reactome:R-HSA-8876616 "DENND6A,B exchange GTP for GDP on RAB14"; Reactome:R-HSA-8876837 "RAB21 GEFs exchange GTP for GDP on RAB21"; Reactome:R-HSA-8877308 "MADD exchanges GTP for GDP on RAB27"; Reactome:R-HSA-8877311 "RAB31 GEFs exchange GTP for GDP on RAB31"; Reactome:R-HSA-8877451 "MON1:CCZ1 exchanges GTP for GDP on RAB7"; Reactome:R-HSA-8877475 "TRAPPC complexes exchange GTP for GDP on RAB1"; Reactome:R-HSA-8877612 "DENND1s exchange GTP for GDP on RAB35"; Reactome:R-HSA-8877760 "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38"; Reactome:R-HSA-8877813 "DENND5A,B exchange GTP for GDP on RAB39"; Reactome:R-HSA-8877998 "RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18"; Reactome:R-HSA-8980691 "RHOA GEFs activate RHOA"; Reactome:R-HSA-9013023 "RHOB GEFs activate RHOB"; Reactome:R-HSA-9013109 "RHOC GEFs activate RHOC"; Reactome:R-HSA-9013143 "RAC1 GEFs activate RAC1"; Reactome:R-HSA-9013159 "CDC42 GEFs activate CDC42"; Reactome:R-HSA-9013435 "RHOD auto-activates"; Reactome:R-HSA-9014296 "RAC2 GEFs activate RAC2"; Reactome:R-HSA-9014433 "RHOG GEFs activate RHOG"; Reactome:R-HSA-9017491 "RHOJ GEFs activate RHOJ"; Reactome:R-HSA-9018747 "RHOQ GEFs activate RHOQ"; Reactome:R-HSA-9018768 "RHOU auto-activates"; Reactome:R-HSA-9018804 "RAC3 GEFs activate RAC3"; Reactome:R-HSA-9018817 "RHOT1 GEFs activate RHOT1"; Reactome:R-HSA-9018825 "RHOT2 GEFs activate RHOT2"; Reactome:R-HSA-9026891 "NTRK2 activates RAS signaling through SHC1"; Reactome:R-HSA-9029158 "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS"; Reactome:R-HSA-9032067 "NTRK2 activates RAS signaling through FRS2"; Reactome:R-HSA-9032798 "DOCK3 activates RAC1"; Reactome:R-HSA-9033292 "NTRK2 and CDK5 promote activation of RAC1 by TIAM1"; Reactome:R-HSA-9036301 "ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s"; Reactome:R-HSA-9607304 "SOS1-mediated nucleotide exchange of RAS downstream of FLT3"; Reactome:R-HSA-9619803 "p-S516-ARHGEF7 activates RAC1"; Reactome:R-HSA-9624845 "RCC1 stimulates GDP to GTP exchange on RAN"; Reactome:R-HSA-9634418 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1"; Reactome:R-HSA-9639286 "RRAGC,D exchanges GTP for GDP"; Reactome:R-HSA-9640167 "RRAGA,B exchanges GDP for GTP"; Reactome:R-HSA-9660824 "ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs"; Reactome:R-HSA-9664991 "RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants"; Reactome:R-HSA-9665009 "RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR"; Reactome:R-HSA-9665404 "RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1"; Reactome:R-HSA-9665408 "RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2"; Reactome:R-HSA-9665700 "RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants"; Reactome:R-HSA-9665707 "RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR"; Reactome:R-HSA-9666428 "DOCK180 exchanges GTP for GDP on RAC1:GDP"; Reactome:R-HSA-9666430 "p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP"; Reactome:R-HSA-9670436 "p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS"; Reactome:R-HSA-9672163 "SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers"; Reactome:R-HSA-9672170 "SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors"; Reactome:R-HSA-9680385 "CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS"; Reactome:R-HSA-9693111 "RHOF auto-activates"; Reactome:R-HSA-9695853 "FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS"; Reactome:R-HSA-9703441 "SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants"; Reactome:R-HSA-9751201 "p-VAV1,2,3 exchange 6TGTP for GDP on RAC1"; reactome:R-HSA-114544 "p115-RhoGEF activation of RHOA"; reactome:R-HSA-1168636 "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP"; reactome:R-HSA-1433415 "Activation of RAC1"; reactome:R-HSA-156913 "Regeneration of eEF1A:GTP by eEF1B activity"; reactome:R-HSA-169904 "C3G stimulates nucleotide exchange on Rap1"; reactome:R-HSA-170979 "(Frs2)C3G stimulates nucleotide exchange on Rap1"; reactome:R-HSA-187746 "RIT/RIN are activated"; reactome:R-HSA-2029451 "Activation of RAC1 by VAV"; reactome:R-HSA-2029467 "Activation of RAC1 by CRKII:DOCK180:ELMO"; reactome:R-HSA-203977 "SAR1 Activation And Membrane Binding"; reactome:R-HSA-205039 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor"; reactome:R-HSA-2424476 "Activation of RAC1 by VAV2/3"; reactome:R-HSA-2485180 "MII catalyses GDP/GTP exchange on Gt"; reactome:R-HSA-2730840 "Activation of RAC1 by VAV"; reactome:R-HSA-354173 "Activation of Rap1 by cytosolic GEFs"; reactome:R-HSA-379044 "Liganded Gs-activating GPCR acts as a GEF for Gs"; reactome:R-HSA-379048 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11"; reactome:R-HSA-380073 "Liganded Gi-activating GPCR acts as a GEF for Gi"; reactome:R-HSA-389348 "Activation of Rac1 by pVav1"; reactome:R-HSA-389350 "Activation of Cdc42 by pVav1"; reactome:R-HSA-392195 "Gi activation by P2Y purinoceptor 12"; reactome:R-HSA-3928592 "p190RhoGEF exchanges GTP for GDP on RHOA, activating it"; reactome:R-HSA-3928612 "KALRN exchanges GTP for GDP on RAC1, activating it"; reactome:R-HSA-3928628 "VAV exchanges GTP for GDP on RAC1, activating it"; reactome:R-HSA-3928632 "ITSN1 exchanges GTP for GDP on CDC42, activating it"; reactome:R-HSA-3928633 "bPIX exchanges GTP for GDP on RAC, activating it"; reactome:R-HSA-3928642 "TIAM1 exchanges GTP for GDP on RAC1, activating it"; reactome:R-HSA-3928651 "NGEF exchanges GTP for GDP on RHOA"; reactome:R-HSA-392870 "Gs activation by prostacyclin receptor"; reactome:R-HSA-3965444 "WNT:FZD complex promotes G-protein nucleotide exchange"; reactome:R-HSA-399995 "Muscarinic Acetylcholine Receptor M3 activates Gq"; reactome:R-HSA-4093336 "p-TIAM1 exchanges GTP for GDP on RAC1, activating it"; reactome:R-HSA-418579 "Gq activation by P2Y purinoceptor 1"; reactome:R-HSA-420883 "Opsins act as GEFs for G alpha-t"; reactome:R-HSA-428750 "Gq activation by TP receptor"; reactome:R-HSA-428917 "G13 activation by TP receptor"; reactome:R-HSA-442291 "VAV2 is a GEF for Rho/Rac family kinases"; reactome:R-HSA-442314 "VAV3 is a GEF for Rho/Rac family kinases"; reactome:R-HSA-445064 "Activation of Rac1 by VAV2"; reactome:R-HSA-5218829 "VEGF induces CDC42 activation by unknown mechanism"; reactome:R-HSA-5218839 "DOCK180:ELMO exchanges GTP for GDP, activating RAC1"; reactome:R-HSA-5218850 "VAV exchanges GTP for GDP on RAC1, activating it"; reactome:R-HSA-5694409 "Nucleotide exchange on RAB1"; reactome:R-HSA-6807868 "GBF1 stimulates ARF nucleotide exchange"; reactome:R-HSA-6811429 "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange"; reactome:R-HSA-749453 "Liganded Gz-activating GPCR acts as a GEF for Gz"; reactome:R-HSA-751029 "Liganded G12/13-activating GPCR acts as a GEF for G12/13"; reactome:R-HSA-825631 "Glucagon:GCGR mediates GTP-GDP exchange"; reactome:R-HSA-8848618 "Activation of RAC1 by the PXN:CRK complex"; reactome:R-HSA-8850041 "RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18"; reactome:R-HSA-8851827 "RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1"; reactome:R-HSA-8851877 "RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET"; reactome:R-HSA-8851899 "RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET"; reactome:R-HSA-8875568 "RAPGEF1 activates RAP1"; reactome:R-HSA-8875591 "DOCK7 activates RAC1"; reactome:R-HSA-8964604 "CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated"; reactome:R-HSA-8982637 "Opsins binds G alpha-t"; reactome:R-HSA-8982640 "G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t)"; reactome:R-HSA-939265 "Activation of Rap1 by membrane-associated GEFs"
G
4930474N05Rikl2 RIKEN cDNA 4930474N05 gene like 2
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,664,310...11,672,032
G
4930596D02Rikl2 RIKEN cDNA 4930596D02 gene like 2
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr17:54,151,572...54,154,198
G
AABR07000583.1 enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
Ensembl chr 1:17,691,637...17,692,974
G
AABR07006688.2 enables
IEA GO_REF:0000118
TreeGrafter GO_REF:0000118
Ensembl chr 1:227,796,499...227,800,519
G
AABR07007642.1 enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
G
AABR07018646.1 enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
Ensembl chr15:59,673,927...59,675,144
G
AABR07036505.1 enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
Ensembl chr16:11,344,202...11,347,032
G
AABR07047293.1 enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
Ensembl chr 5:39,030,901...39,032,104
G
Abr ABR activator of RhoGEF and GTPase
enables
IEA ISO GO_REF:0000043
UniProt RGD Ensembl PMID:7479768 GO_REF:0000043 GO_REF:0000107
NCBI chr10:61,262,516...61,461,331
G
Akap13 A-kinase anchoring protein 13
enables
ISO ISS IEA (PMID:11546812), (PMID:25186459)
RGD UniProt Ensembl PMID:11546812 PMID:23658642 PMID:25186459 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 MGI:5770047
NCBI chr 1:129,313,183...129,619,647
G
Als2 alsin Rho guanine nucleotide exchange factor ALS2
contributes_to
ISO ISS IEA IBA (PMID:15247254)
RGD UniProt Ensembl GO_Central PMID:12837691 PMID:15247254 PMID:16049005 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107
NCBI chr 9:60,613,182...60,686,394
G
Als2cl ALS2 C-terminal like
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:15388334 GO_REF:0000033
NCBI chr 8:110,863,753...110,884,434
G
Ankrd27 ankyrin repeat domain 27
enables
ISO IBA (PMID:16525121)
RGD GO_Central PMID:16525121 GO_REF:0000033
NCBI chr 1:88,251,216...88,303,615
G
Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1
enables
ISO IEA (PMID:15644318)
RGD Ensembl UniProt PMID:15644318 GO_REF:0000043 GO_REF:0000107
NCBI chr 5:8,982,061...9,076,326
G
Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2
enables
TAS ISS ISO IEA GO_REF:0000024
UniProt RGD PMID:10212200 PMID:15385626 PMID:15198677 GO_REF:0000024 GO_REF:0000043, RGD:1304338
NCBI chr 3:155,547,504...155,633,652
G
Arfgef3 ARFGEF family member 3
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr 1:13,245,578...13,404,319
G
Arhgef1 Rho guanine nucleotide exchange factor 1
enables
IEA IBA GO_REF:0000002
InterPro TreeGrafter GO_Central GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 1:80,499,026...80,520,954
G
Arhgef10 Rho guanine nucleotide exchange factor 10
enables
ISO (PMID:16896804), (PMID:19635168), (PMID:20042462)
RGD PMID:16896804 PMID:19635168 PMID:20042462
NCBI chr16:74,647,147...74,738,784
G
Arhgef10l Rho guanine nucleotide exchange factor 10 like
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 5:152,792,247...152,935,255
G
Arhgef11 Rho guanine nucleotide exchange factor 11
enables
IEA IDA IBA GO_REF:0000002
InterPro TreeGrafter GO_Central PMID:11242047 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118, RGD:631920
NCBI chr 2:173,074,383...173,195,962
G
Arhgef12 Rho guanine nucleotide exchange factor 12
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 8:43,350,070...43,475,404
G
Arhgef15 Rho guanine nucleotide exchange factor 15
enables
IDA ISO PMID:12775584
RGD PMID:12775584 PMID:21029865 PMID:12775584 MGI:4881358 , RGD:8554375
NCBI chr10:53,650,521...53,663,269
G
Arhgef16 Rho guanine nucleotide exchange factor 16
enables
ISO (PMID:20679435)
RGD PMID:20679435
NCBI chr 5:164,843,656...164,866,212
G
Arhgef17 Rho guanine nucleotide exchange factor 17
enables
ISO (PMID:12071859)
RGD PMID:12071859
NCBI chr 1:155,230,607...155,290,163
G
Arhgef18 Rho/Rac guanine nucleotide exchange factor 18
enables
ISO (PMID:14512443)
RGD PMID:14512443
NCBI chr12:1,395,035...1,503,082
G
Arhgef19 Rho guanine nucleotide exchange factor 19
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 5:153,536,038...153,554,203
G
Arhgef2 Rho/Rac guanine nucleotide exchange factor 2
enables
ISO IEA ISS (PMID:9857026)
RGD UniProt Ensembl InterPro PMID:9857026 PMID:15996550 GO_REF:0000002 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107
NCBI chr 2:174,061,126...174,118,355
G
Arhgef25 Rho guanine nucleotide exchange factor 25
enables
IEA IBA GO_REF:0000002
InterPro TreeGrafter GO_Central GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 7:63,005,938...63,013,325
G
Arhgef26 Rho guanine nucleotide exchange factor 26
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 2:146,740,336...146,850,918
G
Arhgef28 Rho guanine nucleotide exchange factor 28
enables
ISO IEA (PMID:11058585)
RGD UniProt PMID:11058585 GO_REF:0000043
NCBI chr 2:29,263,888...29,560,595
G
Arhgef3 Rho guanine nucleotide exchange factor 3
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr16:2,301,573...2,581,951
G
Arhgef33 Rho guanine nucleotide exchange factor 33
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 6:14,582,922...14,715,014
G
Arhgef37 Rho guanine nucleotide exchange factor 37
enables
IEA IBA GO_REF:0000002
InterPro TreeGrafter GO_Central GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr18:54,935,256...55,001,017
G
Arhgef38 Rho guanine nucleotide exchange factor 38
enables
IEA IBA GO_REF:0000002
InterPro GO_Central TreeGrafter GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 2:221,610,212...221,739,841
G
Arhgef39 Rho guanine nucleotide exchange factor 39
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 5:57,752,509...57,756,079
G
Arhgef4 Rho guanine nucleotide exchange factor 4
enables
ISO IBA (PMID:17599059)
RGD GO_Central PMID:17599059 GO_REF:0000033
NCBI chr 9:36,861,800...37,005,079
G
Arhgef40 Rho guanine nucleotide exchange factor 40
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr15:24,672,645...24,696,510
G
Arhgef5 Rho guanine nucleotide exchange factor 5
enables
ISO (PMID:15601624)
RGD PMID:15601624
NCBI chr 4:72,087,205...72,112,316
G
Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6
enables
IEA IBA GO_REF:0000043
UniProt InterPro TreeGrafter GO_Central GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118
NCBI chr X:135,145,447...135,264,636
G
Arhgef7 Rho guanine nucleotide exchange factor 7
enables
TAS ISO IEA IBA (PMID:12695502), (PMID:17310244), (PMID:21048939)
RGD UniProt Ensembl GO_Central PMID:12695502 PMID:17310244 PMID:21048939 PMID:21828338 PMID:12226077 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:633693
NCBI chr16:77,671,021...77,782,593
G
Arhgef9 Cdc42 guanine nucleotide exchange factor 9
enables
IEA IBA GO_REF:0000002
InterPro GO_Central GO_REF:0000002 GO_REF:0000033
NCBI chr X:59,919,560...60,077,538
G
Bcar3 BCAR3 adaptor protein, NSP family member
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr 2:210,525,260...210,638,674
G
Bcr BCR activator of RhoGEF and GTPase
enables
ISO (PMID:23940119), (PMID:7479768)
RGD PMID:7479768 PMID:23940119
NCBI chr20:13,469,325...13,596,942
G
Ccdc88a coiled coil domain containing 88A
enables
ISO (PMID:19211784), (PMID:23509302), (PMID:27864364)
RGD PMID:19211784 PMID:23509302 PMID:27864364
NCBI chr14:103,104,091...103,256,112
G
Ccdc88c coiled-coil domain containing 88C
enables
ISO (PMID:26126266)
RGD PMID:26126266
NCBI chr 6:120,169,752...120,289,459
G
Ccz1 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
enables
ISO (PMID:23084991)
RGD PMID:23084991
NCBI chr12:10,601,066...10,624,608
G
Cdrt15l2 CMT1A duplicated region transcript 15 like 2
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,226,012...11,231,967
G
Chrm4 cholinergic receptor, muscarinic 4
IDA RGD
PMID:12048193 RGD:625569
NCBI chr 3:77,893,425...77,901,166
G
Cyth1 cytohesin 1
enables
ISS ISO IEA GO_REF:0000024
UniProt RGD InterPro Ensembl PMID:10652308 PMID:18042453 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:5520046
NCBI chr10:103,402,727...103,485,826
G
Cyth2 cytohesin 2
enables
ISS ISO IEA GO_REF:0000024
UniProt RGD InterPro PMID:18042453 GO_REF:0000002 GO_REF:0000024 MGI:5520046
NCBI chr 1:96,283,182...96,291,094
G
Cyth3 cytohesin 3
enables
ISO ISS IEA (PMID:23940353), (PMID:9707577)
RGD UniProt Ensembl PMID:9707577 PMID:23940353 GO_REF:0000024 GO_REF:0000107
NCBI chr12:10,840,137...10,933,792
G
Cyth4 cytohesin 4
enables
ISO (PMID:10652308)
RGD PMID:10652308
NCBI chr 7:110,152,232...110,176,726
G
Dennd10 DENN domain containing 10
enables
ISO IBA (PMID:30771381)
RGD GO_Central PMID:30771381 GO_REF:0000033
NCBI chr 1:259,950,955...259,974,459
G
Dennd11 DENN domain containing 11
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr 4:69,197,161...69,266,013
G
Dennd1a DENN domain containing 1A
enables
ISO (PMID:20937701)
RGD PMID:20159556 PMID:20937701 MGI:5751677
NCBI chr 3:21,564,749...22,052,057
G
Dennd1b DENN domain containing 1B
enables
ISO (PMID:20937701)
RGD PMID:20937701 PMID:26774822 MGI:5751612
NCBI chr13:50,545,324...50,772,922
G
Dennd1c DENN domain containing 1C
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 9:1,904,040...1,916,329
G
Dennd2a DENN domain containing 2A
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 4:68,233,016...68,332,235
G
Dennd2b DENN domain containing 2B
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 1:163,544,075...163,734,736
G
Dennd2c DENN domain containing 2C
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 2:190,622,357...190,690,489
G
Dennd2d DENN domain containing 2D
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 2:193,973,231...193,992,275
G
Dennd3 DENN domain containing 3
enables
ISO (PMID:20937701)
RGD PMID:20937701 PMID:21718402 MGI:5448516
NCBI chr 7:105,415,870...105,473,583
G
Dennd4a DENN domain containing 4A
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 8:65,322,920...65,436,331
G
Dennd4b DENN domain containing 4B
enables
ISO (PMID:20937701)
RGD PMID:20937701
NCBI chr 2:175,720,473...175,736,425
G
Dennd4c DENN domain containing 4C
enables
ISO (PMID:20937701)
RGD PMID:20937701 PMID:21454697 MGI:5487518
NCBI chr 5:101,272,298...101,369,529
G
Dennd5a DENN domain containing 5A
enables
ISO IEA IBA (PMID:20937701)
RGD UniProt GO_Central PMID:20937701 GO_REF:0000033 GO_REF:0000043
NCBI chr 1:163,928,183...163,994,207
G
Dennd5b DENN domain containing 5B
enables
ISO IBA (PMID:20937701)
RGD GO_Central PMID:20937701 GO_REF:0000033
NCBI chr 4:181,959,597...182,089,661
G
Dennd6a DENN domain containing 6A
enables
ISO (PMID:22595670)
RGD PMID:22595670
NCBI chr16:1,837,019...1,885,420
G
Dennd6b DENN domain containing 6B
enables
ISO (PMID:22595670)
RGD PMID:22595670
NCBI chr 7:120,261,679...120,273,667
G
Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
enables
ISO (PMID:9562621)
RGD PMID:9562621
NCBI chr15:75,820,040...75,850,450
G
Dnmbp dynamin binding protein
enables
ISS ISO IEA IBA GO_REF:0000024
UniProt RGD InterPro Ensembl TreeGrafter GO_Central PMID:14506234 PMID:17015620 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:2682085
NCBI chr 1:242,736,189...242,829,431
G
Dock1 dedicator of cyto-kinesis 1
contributes_to
ISO (PMID:12134158)
RGD PMID:12134158
NCBI chr 1:189,467,143...189,983,777
G
Dock10 dedicator of cytokinesis 10
enables
ISO (MGI:5825418|PMID:25851601), (PMID:15710388)
RGD PMID:15710388 PMID:25851601 MGI:5825418
NCBI chr 9:81,843,599...82,101,540
G
Dock11 dedicator of cytokinesis 11
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:15710388 PMID:22494997 PMID:25851601 GO_REF:0000033 MGI:5825418 MGI:5825422
NCBI chr X:115,131,720...115,314,854
G
Dock2 dedicator of cytokinesis 2
enables
ISO (PMID:10559471)
RGD PMID:10559471
NCBI chr10:18,827,237...19,244,832
G
Dock3 dedicator of cyto-kinesis 3
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 8:107,552,462...107,903,527
G
Dock4 dedicator of cytokinesis 4
enables
ISO IBA (PMID:16464467)
RGD GO_Central PMID:16464467 GO_REF:0000033
NCBI chr 6:57,512,929...57,902,597
G
Dock5 dedicator of cytokinesis 5
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:18396277 PMID:27505886 GO_REF:0000033 MGI:3784815
NCBI chr15:41,979,728...42,158,733
G
Dock6 dedicator of cytokinesis 6
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 8:20,342,430...20,394,660
G
Dock7 dedicator of cytokinesis 7
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 5:113,599,371...113,782,871
G
Dock8 dedicator of cytokinesis 8
enables
ISO IBA (PMID:28028151)
RGD GO_Central PMID:22461490 PMID:28028151 GO_REF:0000033
NCBI chr 1:222,649,309...222,842,474
G
Dock9 dedicator of cytokinesis 9
enables
IEA ISS ISO GO_REF:0000043
UniProt RGD PMID:15710388 PMID:25851601 GO_REF:0000024 GO_REF:0000043 MGI:5825418
NCBI chr15:98,611,518...98,883,306
G
Ect2 epithelial cell transforming 2
enables
ISO (PMID:15254234), (PMID:15545273)
RGD PMID:15254234 PMID:15545273
NCBI chr 2:109,975,813...110,037,911
G
Ect2l epithelial cell transforming 2 like
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 1:12,775,705...12,857,538
G
Eef1b2 eukaryotic translation elongation factor 1 beta 2
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 9:64,580,163...64,582,737
G
Eef1d eukaryotic translation elongation factor 1 delta
enables
IEA IBA GO_REF:0000118
TreeGrafter GO_Central GO_REF:0000033 GO_REF:0000118
NCBI chr 7:107,581,930...107,596,735
G
Egf epidermal growth factor
enables
ISO IEA (PMID:20353436)
RGD Ensembl PMID:20353436 GO_REF:0000107
NCBI chr 2:218,219,408...218,302,359
G
Eif2b1 eukaryotic translation initiation factor 2B subunit alpha
contributes_to
IDA ISO ISS IEA IBA (PMID:11323413)
RGD UniProt Ensembl GO_Central TreeGrafter PMID:11323413 PMID:25858979 PMID:27023709 PMID:9631509 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:11041878
NCBI chr12:32,025,593...32,033,848
G
Eif2b2 eukaryotic translation initiation factor 2B subunit beta
contributes_to
IDA ISO IEA ISS IBA (PMID:11323413), (PMID:15054402)
RGD Ensembl UniProt GO_Central TreeGrafter
PMID:11323413 PMID:15054402 PMID:25858979 PMID:27023709 PMID:9631509 PMID:9582312 More...
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:11041878 , RGD:1581075
NCBI chr 6:104,866,926...104,873,351
G
Eif2b3 eukaryotic translation initiation factor 2B subunit gamma
contributes_to
IDA ISS ISO IEA IBA GO_REF:0000024
UniProt RGD Ensembl TreeGrafter GO_Central
PMID:11323413 PMID:15054402 PMID:25858979 PMID:27023709 PMID:9139680 PMID:9582312 PMID:9798914 PMID:9631509 More...
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:1581073 , RGD:1581075 , RGD:1581077 , RGD:11041878
NCBI chr 5:130,492,167...130,558,692
G
Eif2b4 eukaryotic translation initiation factor 2B subunit delta
contributes_to
IDA ISS ISO IEA GO_REF:0000024
UniProt RGD Ensembl
PMID:11323413 PMID:15054402 PMID:25858979 PMID:27023709 PMID:9139680 PMID:9582312 PMID:9631509 More...
GO_REF:0000024 GO_REF:0000107, RGD:1581073 , RGD:1581075 , RGD:11041878
NCBI chr 6:25,183,177...25,188,832
G
Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon
contributes_to
IDA IMP ISO ISS IBA (PMID:11323413)
RGD UniProt GO_Central
PMID:11323413 PMID:15054402 PMID:25858979 PMID:27023709 PMID:9139680 PMID:9582312 PMID:11500362 PMID:9631509 PMID:10858531 PMID:9139680 More...
GO_REF:0000024 GO_REF:0000033, RGD:1581073 , RGD:1581075 , RGD:1581085 , RGD:11041878 , RGD:8553751 , RGD:1581073
NCBI chr11:80,394,433...80,404,468
G
Elmo1 engulfment and cell motility 1
contributes_to
ISO (PMID:12134158)
RGD PMID:12134158
NCBI chr17:44,286,495...44,822,668
G
ENSRNOG00000063958 enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
Ensembl chr16:11,723,738...11,725,865
G
ENSRNOG00000066475 enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
Ensembl chr 7:1,169,039...1,178,734
G
ENSRNOG00000066767 enables
IEA GO_REF:0000002
InterPro TreeGrafter GO_REF:0000002 GO_REF:0000118
Ensembl chr 2:146,621,513...146,622,884
G
ENSRNOG00000066806 enables
IEA GO_REF:0000118
TreeGrafter GO_REF:0000118
Ensembl chr15:31,017,340...31,017,939
G
ENSRNOG00000070167 enables
IEA GO_REF:0000118
TreeGrafter GO_REF:0000118
Ensembl chr20:31,012,060...31,012,587
G
Eps8l1 EPS8-like 1
contributes_to
ISO (PMID:14565974)
RGD PMID:14565974
NCBI chr 1:69,343,202...69,359,778
G
Eps8l2 EPS8-like 2
contributes_to
ISO (PMID:14565974)
RGD PMID:14565974
NCBI chr 1:196,446,260...196,471,544
G
Eps8l3 EPS8 like 3
enables
ISO (PMID:14565974)
RGD PMID:14565974
NCBI chr 2:195,514,692...195,528,085
G
Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1
enables
IMP IEA IBA ISO PMID:23209303
UniProt GO_Central RGD PMID:35676269 PMID:23209303 GO_REF:0000033 GO_REF:0000043, RGD:8554251
NCBI chr15:98,124,304...98,363,299
G
Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2
enables
ISO IBA (MGI:5487879|PMID:23375260)
RGD GO_Central PMID:12351724 PMID:23375260 GO_REF:0000033 MGI:5487879
NCBI chr 9:94,053,650...94,161,982
G
Fbxo8 F-box protein 8
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr16:33,665,305...33,711,215
G
Fgd1 FYVE, RhoGEF and PH domain containing 1
enables
ISO (PMID:8969170)
RGD PMID:8969170
NCBI chr X:20,023,746...20,066,734
G
Fgd2 FYVE, RhoGEF and PH domain containing 2
enables
ISO IBA (PMID:18838382)
RGD GO_Central PMID:18838382 GO_REF:0000033
NCBI chr20:7,424,795...7,441,603
G
Fgd3 FYVE, RhoGEF and PH domain containing 3
enables
IEA IBA GO_REF:0000002
InterPro GO_Central GO_REF:0000002 GO_REF:0000033
NCBI chr17:15,324,848...15,387,271
G
Fgd4 FYVE, RhoGEF and PH domain containing 4
enables
IEA IBA GO_REF:0000002
InterPro UniProt GO_Central GO_REF:0000002 GO_REF:0000033 GO_REF:0000043
NCBI chr11:84,399,989...84,551,013
G
Fgd5 FYVE, RhoGEF and PH domain containing 5
enables
IEA IBA GO_REF:0000002
InterPro GO_Central GO_REF:0000002 GO_REF:0000033
NCBI chr 4:124,497,061...124,594,564
G
Fgd6 FYVE, RhoGEF and PH domain containing 6
enables
IEA IBA GO_REF:0000002
InterPro GO_Central GO_REF:0000002 GO_REF:0000033
NCBI chr 7:28,597,609...28,712,908
G
Frmd7 FERM domain containing 7
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr X:130,375,925...130,423,836
G
Gapvd1 GTPase activating protein and VPS9 domains 1
enables
ISO IBA (PMID:16410077)
RGD GO_Central PMID:16410077 PMID:17189207 GO_REF:0000033 MGI:3790294
NCBI chr 3:17,968,345...18,041,888
G
Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr 1:245,018,535...245,147,052
G
Gripap1 GRIP1 associated protein 1
IMP RGD
PMID:10896157 RGD:632892
NCBI chr X:14,678,896...14,708,747
G
Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
contributes_to
ISO IBA (PMID:23084991)
RGD GO_Central PMID:23084991 GO_REF:0000033
NCBI chr 1:241,551,180...241,577,292
G
Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
contributes_to
ISO IBA (PMID:23084991)
RGD GO_Central PMID:23084991 GO_REF:0000033
NCBI chr12:44,264,037...44,294,791
G
Iqsec1 IQ motif and Sec7 domain ArfGEF 1
enables
IEA GO_REF:0000043
UniProt InterPro GO_REF:0000002 GO_REF:0000043
NCBI chr 4:123,168,719...123,488,300
G
Iqsec2 IQ motif and Sec7 domain ArfGEF 2
enables
ISO (PMID:26793055)
RGD PMID:26793055
NCBI chr X:21,254,799...21,337,179
G
Iqsec3 IQ motif and Sec7 domain ArfGEF 3
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 4:154,610,933...154,707,310
G
Itsn1 intersectin 1
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr11:30,978,590...31,160,645
G
Itsn2 intersectin 2
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 6:27,616,645...27,727,373
G
Kalrn kalirin, RhoGEF kinase
enables
TAS ISO IEA IBA PMID:12177196
RGD InterPro UniProt TreeGrafter GO_Central PMID:12546821 PMID:12177196 PMID:12177196 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118, RGD:628431 , RGD:628431
NCBI chr11:66,198,155...66,803,166
G
Kndc1 kinase non-catalytic C-lobe domain containing 1
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:17984326 GO_REF:0000033
NCBI chr 1:194,689,962...194,738,353
G
Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
contributes_to
ISO ISS IBA IEA (PMID:22980980)
RGD UniProt GO_Central TreeGrafter PMID:22980980 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118
NCBI chr 1:156,272,116...156,277,687
G
Lamtor1l1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1
contributes_to
ISS IBA IEA GO_REF:0000024
UniProt GO_Central TreeGrafter GO_REF:0000024 GO_REF:0000033 GO_REF:0000118
NCBI chr X:34,637,460...34,638,509
G
Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
contributes_to
ISO (PMID:22980980)
RGD PMID:22980980
NCBI chr 2:174,008,556...174,011,950
G
Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
contributes_to
ISO ISS IEA (PMID:22980980)
RGD UniProt Ensembl PMID:22980980 GO_REF:0000024 GO_REF:0000107
NCBI chr 2:226,411,389...226,423,612
G
Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
contributes_to
ISO IBA (PMID:22980980)
RGD GO_Central PMID:22980980 GO_REF:0000033
NCBI chr12:17,258,656...17,262,478
G
Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
contributes_to
ISO IBA (PMID:22980980)
RGD GO_Central PMID:22980980 GO_REF:0000033
NCBI chr 2:194,900,038...194,905,394
G
LOC100911649 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,435,459...11,438,066
G
LOC102551632 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,293,983...11,321,792
G
LOC102552466 uncharacterized LOC102552466
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,409,036...11,427,387
G
LOC102553208 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr17:54,780,591...54,783,184
G
LOC108353077 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,121,513...11,128,582
G
LOC108353078 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,371,437...11,377,948
G
LOC120093097 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr10:40,323,007...40,325,012
G
LOC120095104 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr10:40,279,251...40,281,351
G
LOC120097482 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,269,061...11,277,700
G
LOC120097781 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr17:54,720,780...54,728,358
G
LOC120100841 guanine nucleotide exchange factor MSS4-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr 2:153,400,400...153,447,089
G
LOC134482318 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
G
LOC134482319 ral guanine nucleotide dissociation stimulator-like
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
G
Madd MAP-kinase activating death domain
enables
IDA ISO ISS IEA IBA (PMID:20937701), (PMID:9115275)
RGD UniProt GO_Central PMID:9115275 PMID:20937701 PMID:9224661 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043, RGD:9588648
NCBI chr 3:77,114,330...77,157,865
G
Mcf2 MCF.2 cell line derived transforming sequence
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:8464478 GO_REF:0000033
NCBI chr X:138,414,077...138,514,828
G
Mcf2l MCF.2 cell line derived transforming sequence-like
enables
ISO IDA IEA IBA (PMID:15157669)
RGD InterPro UniProt TreeGrafter GO_Central PMID:12637522 PMID:15157669 PMID:7957046 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118, RGD:729022
NCBI chr16:76,507,133...76,652,893
G
Mettl6 methyltransferase 6, tRNA N3-cytidine
enables
IEA GO_REF:0000104
UniProt GO_REF:0000104
NCBI chr16:6,683,820...6,699,013
G
Mon1a MON1 homolog A, secretory trafficking associated
enables
ISO (PMID:23084991)
RGD PMID:23084991
NCBI chr 8:108,574,272...108,593,163
G
Mycbp2 MYC binding protein 2
enables
ISO (PMID:26304119)
RGD PMID:26304119
NCBI chr15:79,937,354...80,175,432
G
Net1 neuroepithelial cell transforming 1
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr17:66,341,251...66,370,445
G
Ngef neuronal guanine nucleotide exchange factor
enables
ISO IEA (PMID:15848799)
RGD InterPro PMID:15848799 GO_REF:0000002
NCBI chr 9:88,146,956...88,244,454
G
Nucb1 nucleobindin 1
enables
IDA PMID:21653697
UniProt
PMID:21653697 RGD:14929204
NCBI chr 1:95,968,325...95,999,183
G
Nucb2 nucleobindin 2
enables
IDA PMID:21653697
UniProt
PMID:21653697 RGD:14929204
NCBI chr 1:170,750,830...170,787,356
G
Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
NAS RGD
PMID:12631729 RGD:633514
NCBI chr10:43,774,113...43,919,718
G
Pcp2 Purkinje cell protein 2
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:10196137 GO_REF:0000033
NCBI chr12:1,681,659...1,683,899
G
Plcd4 phospholipase C, delta 4
enables
ISO (PMID:30194280)
RGD PMID:30194280
NCBI chr 9:76,115,523...76,158,602
G
Plce1 phospholipase C, epsilon 1
enables
IEA GO_REF:0000043
UniProt InterPro GO_REF:0000002 GO_REF:0000043
NCBI chr 1:236,243,445...236,552,571
G
Plcg1 phospholipase C, gamma 1
enables
IDA PMID:15252117
UniProt
PMID:15252117 RGD:401827133
NCBI chr 3:149,385,587...149,416,330
G
Plekhg1 pleckstrin homology and RhoGEF domain containing G1
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 1:40,348,684...40,434,063
G
Plekhg2 pleckstrin homology and RhoGEF domain containing G2
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 1:83,651,902...83,665,063
G
Plekhg3 pleckstrin homology and RhoGEF domain containing G3
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 6:95,265,756...95,308,952
G
Plekhg4 pleckstrin homology and RhoGEF domain containing G4
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr19:33,251,788...33,266,490
G
Plekhg5 pleckstrin homology and RhoGEF domain containing G5
enables
IEA ISO GO_REF:0000002
InterPro RGD PMID:16467373 GO_REF:0000002
NCBI chr 5:162,577,999...162,621,518
G
Plekhg6 pleckstrin homology and RhoGEF domain containing G6
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 4:158,163,443...158,182,628
G
Preb prolactin regulatory element binding
enables
ISS IEA ISO GO_REF:0000024
UniProt InterPro Ensembl RGD PMID:11422940 PMID:32358066 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:5784996
NCBI chr 6:25,418,805...25,422,594
G
Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 3:155,306,950...155,456,688
G
Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
enables
ISO IBA (PMID:15304343)
RGD GO_Central PMID:15304343 GO_REF:0000033
NCBI chr 5:7,937,692...8,253,112
G
Psd pleckstrin and Sec7 domain containing
enables
ISS ISO IEA GO_REF:0000024
UniProt RGD InterPro Ensembl PMID:23603394 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107
NCBI chr 1:245,173,279...245,188,681
G
Psd2 pleckstrin and Sec7 domain containing 2
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr18:27,564,912...27,616,674
G
Psd3 pleckstrin and Sec7 domain containing 3
enables
ISO (PMID:16707115)
RGD PMID:16707115
NCBI chr16:21,465,643...22,035,846
G
Psd4 pleckstrin and Sec7 domain containing 4
enables
IEA GO_REF:0000002
InterPro GO_REF:0000002
NCBI chr 3:7,137,069...7,173,571
G
Pycr3 pyrroline-5-carboxylate reductase 3
enables
IEA GO_REF:0000118
TreeGrafter GO_REF:0000118
NCBI chr 7:107,603,543...107,608,831
G
Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1
contributes_to
ISO IEA (PMID:24891604)
RGD Ensembl PMID:24891604 GO_REF:0000107
NCBI chr13:39,355,698...39,429,154
G
Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2
contributes_to
ISO IEA (PMID:24891604)
RGD Ensembl PMID:24891604 GO_REF:0000107
NCBI chr13:96,757,430...96,828,930
G
Rab3il1 RAB3A interacting protein-like 1
enables
IDA ISO IEA (PMID:20937701)
RGD InterPro Ensembl PMID:20937701 PMID:11516400 GO_REF:0000002 GO_REF:0000107, RGD:632896
NCBI chr 1:206,646,168...206,682,718
G
Rab3ip RAB3A interacting protein
enables
IDA ISO ISS IEA (PMID:20937701)
RGD UniProt InterPro PMID:20937701 PMID:12221131 GO_REF:0000002 GO_REF:0000024, RGD:11534981
NCBI chr 7:52,531,461...52,575,295
G
Rabgef1 RAB guanine nucleotide exchange factor 1
enables
ISO IBA (PMID:20937701), (PMID:23382462)
RGD GO_Central PMID:20937701 PMID:23382462 GO_REF:0000033
NCBI chr12:26,459,190...26,503,790
G
Rabif RAB interacting factor
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr13:45,936,371...45,948,929
G
Ralgds ral guanine nucleotide dissociation stimulator
enables
TAS IEA IBA GO_REF:0000043
UniProt Reactome GO_Central PMID:8094051 GO_REF:0000033 GO_REF:0000043 Reactome:R-RNO-187759 Reactome:R-RNO-187762, RGD:69953
NCBI chr 3:11,839,686...11,880,059
G
Ralgds-ps4 ral guanine nucleotide dissociation stimulator, pseudogene 4
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,398,874...11,402,678
G
Ralgdsl1 ral guanine nucleotide dissociation stimulator like 1
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr13:64,634,489...64,904,170
G
Ralgdsl11 ral guanine nucleotide dissociation stimulator like 11
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,180,700...11,189,203
G
Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2
enables
ISO (PMID:24069211)
RGD PMID:24069211
NCBI chr20:4,948,495...4,956,774
G
Ralgdsl3 ral guanine nucleotide dissociation stimulator like 3
enables
ISO (PMID:10869344)
RGD PMID:10869344
NCBI chr 8:20,500,846...20,520,471
G
Ralgdsl4 ral guanine nucleotide dissociation stimulator like 4
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,644,655...11,649,507
G
Ralgdsl6 ral guanine nucleotide dissociation stimulator like 6
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,203,355...11,209,558
G
Ralgdsl7 ral guanine nucleotide dissociation stimulator like 7
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr10:40,267,536...40,269,571
G
Ralgdsl8 ral guanine nucleotide dissociation stimulator like 8
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr17:54,800,565...54,808,145
G
Ralgdsl9 ral guanine nucleotide dissociation stimulator like 9
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,156,428...11,160,928
G
Ralgps1 Ral GEF with PH domain and SH3 binding motif 1
enables
ISO IBA (PMID:10747847)
RGD GO_Central PMID:10747847 GO_REF:0000033
NCBI chr 3:16,433,323...16,670,276
G
Ralgps2 Ral GEF with PH domain and SH3 binding motif 2
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr13:68,924,674...69,104,637
G
Ranbp10 RAN binding protein 10
enables
ISO (PMID:18347012)
RGD PMID:18347012
NCBI chr19:33,656,046...33,716,864
G
Rangrf RAN guanine nucleotide release factor
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:10811801 GO_REF:0000033
NCBI chr10:53,677,467...53,678,880
G
Rap1a RAP1A, member of RAS oncogene family
enables
IMP PMID:17724123
UniProt
PMID:17724123 RGD:8554481
NCBI chr 2:193,208,631...193,286,513
G
Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1
enables
ISO (PMID:21242305), (PMID:28630045), (PMID:30190425)
RGD PMID:21242305 PMID:28630045 PMID:30190425
NCBI chr 2:227,500,366...227,645,213
G
Rapgef1 Rap guanine nucleotide exchange factor 1
enables
ISO IBA (PMID:10548487), (PMID:21840392)
RGD GO_Central PMID:10548487 PMID:12671687 PMID:14712229 PMID:21840392 GO_REF:0000033
NCBI chr 3:12,898,349...13,016,234
G
Rapgef2 Rap guanine nucleotide exchange factor 2
enables
ISS ISO IBA GO_REF:0000024
UniProt RGD GO_Central
PMID:10608883 PMID:10801446 PMID:12391161 PMID:16272156 PMID:19635461 PMID:23800469 More...
GO_REF:0000024 GO_REF:0000033 MGI:4359570 MGI:5499726 MGI:5514088
NCBI chr 2:164,207,513...164,322,157
G
Rapgef3 Rap guanine nucleotide exchange factor 3
enables
ISS IEA ISO IBA GO_REF:0000024
UniProt RGD Ensembl GO_Central PMID:14712229 PMID:15334074 PMID:16076873 PMID:21840392 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107
NCBI chr 7:128,875,772...128,898,203
G
Rapgef4 Rap guanine nucleotide exchange factor 4
enables
IDA ISS IEA ISO IBA GO_REF:0000024
UniProt Ensembl RGD GO_Central PMID:11056535 PMID:15334074 PMID:16076873 PMID:18660803 PMID:9856955 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:632397
NCBI chr 3:56,809,388...57,101,332
G
Rapgef5 Rap guanine nucleotide exchange factor 5
enables
ISO IEA IBA (PMID:10486569)
RGD UniProt GO_Central PMID:10486569 GO_REF:0000033 GO_REF:0000043
NCBI chr 6:138,445,184...138,679,943
G
Rapgef6 Rap guanine nucleotide exchange factor 6
enables
ISO IBA (PMID:11524421)
RGD GO_Central PMID:11524421 GO_REF:0000033
NCBI chr10:38,655,854...38,824,227
G
Rapgefl1 Rap guanine nucleotide exchange factor like 1
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr10:83,793,711...83,810,373
G
Rasgef1a RasGEF domain family, member 1A
enables
ISO IBA (PMID:17121879), (PMID:19645719)
RGD GO_Central PMID:17121879 PMID:19645719 GO_REF:0000033
NCBI chr 4:151,187,533...151,267,982
G
Rasgef1b RasGEF domain family, member 1B
enables
ISO IBA (PMID:19645719)
RGD GO_Central PMID:19645719 GO_REF:0000033
NCBI chr14:9,859,512...10,380,044
G
Rasgef1c RasGEF domain family, member 1C
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr10:34,227,483...34,293,676
G
Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1
enables
ISO IEA IBA (PMID:27856453)
RGD Ensembl UniProt GO_Central PMID:27856453 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107
NCBI chr 8:90,445,154...90,574,274
G
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2
enables
ISO IEA IBA (PMID:27856453)
RGD InterPro Ensembl GO_Central PMID:27856453 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107
NCBI chr 2:23,113,613...23,361,537
G
Rasgrp1 RAS guanyl releasing protein 1
enables
TAS ISO IEA IBA (PMID:23908768)
RGD UniProt Ensembl GO_Central PMID:23908768 PMID:9789079 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:633848
NCBI chr 3:104,168,549...104,230,107
G
Rasgrp2 RAS guanyl releasing protein 2
enables
ISO IEA IBA (PMID:24958846)
RGD Ensembl GO_Central PMID:24958846 GO_REF:0000033 GO_REF:0000107
NCBI chr 1:203,705,777...203,722,993
G
Rasgrp3 RAS guanyl releasing protein 3
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:15545601 GO_REF:0000033
NCBI chr 6:19,895,361...19,993,945
G
Rasgrp4 RAS guanyl releasing protein 4
enables
ISO ISS IEA IBA (PMID:11880369)
RGD UniProt Ensembl GO_Central PMID:11880369 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107
NCBI chr 1:84,433,033...84,452,841
G
Rcc1 regulator of chromosome condensation 1
enables
ISO IBA (PMID:11336674), (PMID:1944575)
RGD GO_Central PMID:1944575 PMID:11336674 PMID:18347012 GO_REF:0000033
NCBI chr 5:144,526,025...144,544,445
G
Rcc1l RCC1 like
enables
ISO IBA (PMID:28746876)
RGD GO_Central PMID:28746876 GO_REF:0000033
NCBI chr12:22,543,125...22,574,042
G
RGD1359108 similar to RIKEN cDNA 3110043O21
contributes_to
ISO IEA (PMID:27103069), (PMID:27617292)
RGD Ensembl InterPro PMID:27103069 PMID:27617292 GO_REF:0000002 GO_REF:0000107
NCBI chr 5:49,766,340...49,791,434
G
Rgl4 ral guanine nucleotide dissociation stimulator like 4
enables
IEA GO_REF:0000043
UniProt GO_REF:0000043
NCBI chr16:11,333,283...11,335,800
G
Rgp1 RGP1 homolog, RAB6A GEF complex partner 1
enables
ISO (PMID:23091056)
RGD PMID:23091056
NCBI chr 5:57,834,467...57,843,087
G
Ric1 RIC1 homolog, RAB6A GEF complex partner 1
enables
ISO (PMID:23091056)
RGD PMID:23091056
NCBI chr 1:227,285,510...227,384,553
G
Ric8a RIC8 guanine nucleotide exchange factor A
enables
IDA IEA IBA PMID:21158412
UniProt GO_Central PMID:12509430 PMID:21158412 PMID:12509430 GO_REF:0000033 GO_REF:0000104, RGD:633903 , RGD:8553612 , RGD:633903
NCBI chr 1:195,935,162...195,941,469
G
Ric8b RIC8 guanine nucleotide exchange factor B
enables
IEA IBA GO_REF:0000104
UniProt GO_Central GO_REF:0000033 GO_REF:0000104
NCBI chr 7:18,746,716...18,843,264
G
Rin1 Ras and Rab interactor 1
enables
IEA IBA GO_REF:0000002
InterPro GO_Central TreeGrafter GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 1:202,355,729...202,362,731
G
Rin2 Ras and Rab interactor 2
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 3:133,086,858...133,303,604
G
Rin3 Ras and Rab interactor 3
enables
ISO IBA (PMID:21586568), (PMID:23185384)
RGD GO_Central PMID:21586568 PMID:23185384 GO_REF:0000033
NCBI chr 6:121,431,776...121,540,956
G
Rinl Ras and Rab interactor-like
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:21419809 GO_REF:0000033
NCBI chr 1:84,077,011...84,088,590
G
Sbf1 SET binding factor 1
enables
ISO IBA (PMID:20937701)
RGD GO_Central PMID:20937701 GO_REF:0000033
NCBI chr 7:120,358,338...120,385,022
G
Sbf2 SET binding factor 2
enables
ISO IBA (PMID:20937701)
RGD GO_Central PMID:20937701 GO_REF:0000033
NCBI chr 1:164,352,892...164,719,883
G
Sec61b SEC61 translocon subunit beta
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr 5:61,773,594...61,781,804
G
Sh2d3c SH2 domain containing 3C
enables
IEA GO_REF:0000043
UniProt InterPro GO_REF:0000002 GO_REF:0000043
NCBI chr 3:16,010,622...16,046,491
G
Sh3bp5 SH3-domain binding protein 5
enables
ISS ISO IEA GO_REF:0000024
UniProt RGD PMID:26506309 PMID:30217979 GO_REF:0000024 GO_REF:0000104
NCBI chr16:6,583,462...6,678,344
G
Sh3bp5l SH3 binding domain protein 5 like
enables
ISO (PMID:30217979)
RGD PMID:30217979
NCBI chr10:42,512,437...42,529,564
G
Slc38a9 solute carrier family 38, member 9
enables
ISS ISO GO_REF:0000024
UniProt RGD PMID:30181260 GO_REF:0000024
NCBI chr 2:44,291,637...44,374,897
G
Smcr8 SMCR8-C9orf72 complex subunit
contributes_to
ISO (PMID:27103069), (PMID:27617292)
RGD PMID:27103069 PMID:27617292
NCBI chr10:45,457,962...45,465,101
G
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
enables
ISO TAS IBA (PMID:1371879), (PMID:16483568), (PMID:7731718)
RGD Reactome GO_Central
PMID:1371879 PMID:7731718 PMID:7799946 PMID:8479536 PMID:11524436 PMID:15644420 PMID:15728722 PMID:16203968 PMID:16483568 PMID:17721087 PMID:24222714 PMID:29844066 More...
GO_REF:0000033 MGI:3607660 MGI:3613346 MGI:6214787 Reactome:R-NUL-9032387
NCBI chr 6:14,533,870...14,613,348
G
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
enables
IBA ISO GO_REF:0000033
GO_Central RGD PMID:14712229 PMID:15728722 GO_REF:0000033
NCBI chr 6:88,042,966...88,156,140
G
Spata13 spermatogenesis associated 13
enables
ISO IBA (PMID:17145773), (PMID:17599059), (PMID:19934221)
RGD GO_Central PMID:17145773 PMID:17599059 PMID:19934221 GO_REF:0000033
NCBI chr15:34,778,479...34,907,645
G
Thg1l tRNA-histidine guanylyltransferase 1-like
enables
ISO IEA (PMID:25008184)
RGD Ensembl PMID:25008184 GO_REF:0000107
NCBI chr10:30,387,929...30,396,579
G
Tiam1 TIAM Rac1 associated GEF 1
enables
ISS ISO GO_REF:0000024
SynGO RGD PMID:12525493 PMID:15721239 PMID:20361982 PMID:23109420 PMID:25684205 GO_REF:0000024 MGI:5466648
NCBI chr11:29,031,347...29,380,153
G
Tiam2 TIAM Rac1 associated GEF 2
enables
ISO (PMID:10364228)
RGD PMID:10364228
NCBI chr 1:43,918,179...44,119,499
G
Trio trio Rho guanine nucleotide exchange factor
enables
IEA IBA GO_REF:0000043
UniProt GO_Central GO_REF:0000033 GO_REF:0000043
NCBI chr 2:78,505,069...78,801,384
G
Vav1 vav guanine nucleotide exchange factor 1
enables
TAS ISO IEA IBA (PMID:8990121)
RGD UniProt Ensembl GO_Central
PMID:8990121 PMID:15249579 PMID:15644420 PMID:16203968 PMID:17721087 PMID:10395673 More...
GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 MGI:3607660 MGI:3613346 MGI:6214787 , RGD:727273
NCBI chr 9:2,161,985...2,209,951
G
Vav2 vav guanine nucleotide exchange factor 2
enables
ISO IBA (PMID:8990121)
RGD GO_Central PMID:8990121 PMID:15728722 GO_REF:0000033
NCBI chr 3:10,584,688...10,754,128
G
Vav3 vav guanine nucleotide exchange factor 3
enables
ISO IBA (PMID:8990121)
RGD GO_Central PMID:8990121 PMID:15249579 PMID:15728722 GO_REF:0000033
NCBI chr 2:197,011,901...197,354,321
G
Vps9d1 VPS9 domain containing 1
enables
IBA GO_REF:0000033
GO_Central GO_REF:0000033
NCBI chr19:51,276,998...51,290,726
G
Wdr41 WD repeat domain 41
contributes_to
ISO (PMID:27103069)
RGD PMID:27103069
NCBI chr 2:26,222,797...26,273,849
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