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ONTOLOGY REPORT - ANNOTATIONS

Term:transmembrane receptor protein tyrosine kinase adaptor activity
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Accession:GO:0005068 term browser browse the term
Definition:The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.
Synonyms:exact_synonym: transmembrane receptor protein tyrosine kinase adaptor protein activity
 related_synonym: transmembrane receptor protein tyrosine kinase docking protein activity
 alt_id: GO:0005069


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transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dok2 docking protein 2 enables ISO PR:P25911 (PMID:10428862) RGD PMID:10428862 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 enables IBA
ISO		 GO_REF:0000033
(PMID:9182757)		 GO_Central
RGD		 PMID:9182757 GO_REF:0000033 NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 enables IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382 		JBrowse link
G Gab2 GRB2-associated binding protein 2 enables ISO
ISS
IEA
IBA		 (PMID:19172738)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:19172738 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Grb2 growth factor receptor bound protein 2 enables IEA
ISO		 GO_REF:0000107
MGI:108088 (PMID:17881575)		 Ensembl
RGD		 PMID:17881575 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Irs1 insulin receptor substrate 1 enables IMP
ISO		 PMID:18285345
(PMID:11784871), (PMID:12483226), (PMID:8649419)		 RGD PMID:8649419 PMID:11784871 PMID:12483226 PMID:18285345 RGD:8553881 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 enables ISO (PMID:7534300) RGD PMID:7534300 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 TAS RGD PMID:11859092 RGD:625637 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 enables IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 enables IEA
IBA
ISO		 GO_REF:0000118
GO_REF:0000033
(PMID:10196204)		 TreeGrafter
GO_Central
RGD		 PMID:10196204 GO_REF:0000033 GO_REF:0000118 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Shc1 SHC adaptor protein 1 enables IEA
ISO		 GO_REF:0000107
(PMID:12483226), (PMID:7799946)		 Ensembl
RGD		 PMID:7799946 PMID:12483226 GO_REF:0000107 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Stap1 signal transducing adaptor family member 1 enables ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Tradd TNFRSF1A-associated via death domain enables ISO
IBA		 UniProtKB:Q13546 (PMID:8612133)
GO_REF:0000033		 RGD
GO_Central		 PMID:8612133 GO_REF:0000033 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    molecular adaptor activity 1137
      protein-macromolecule adaptor activity 976
        signaling adaptor activity 102
          signaling receptor complex adaptor activity 40
            transmembrane receptor protein tyrosine kinase adaptor activity 14
Path 2
Term Annotations click to browse term
  molecular_function 20890
    binding 17950
      protein binding 14727
        enzyme binding 2361
          kinase binding 890
            protein kinase binding 798
              protein tyrosine kinase binding 134
                receptor tyrosine kinase binding 85
                  transmembrane receptor protein tyrosine kinase adaptor activity 14
paths to the root