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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor receptor activity
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Accession:GO:0005021 term browser browse the term
Definition:Combining with a vascular endothelial growth factor (VEGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: VEGF receptor activity;   VEGF-activated receptor activity;   VEGFR activity;   vascular endothelial growth factor E-activated receptor activity;   vascular endothelial growth factor-activated receptor activity
 narrow_synonym: VEGF-A-activated receptor activity;   VEGF-B-activated receptor activity;   VEGF-C-activated receptor activity;   VEGF-D-activated receptor activity;   VEGF-E-activated receptor activity
 alt_id: GO:0036326;   GO:0036327;   GO:0036328;   GO:0036329;   GO:0036330



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vascular endothelial growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 Fms related receptor tyrosine kinase 1 enables IMP
ISO
IEA
IBA
(PMID:11312102), (PMID:1312256), (PMID:15952180), (PMID:8605350), (PMID:9299537)
GO_REF:0000117
GO_REF:0000033
(PMID:8356051)
RGD
UniProt
GO_Central
PMID:1312256 PMID:8356051 PMID:8605350 PMID:9299537 PMID:11312102 More... GO_REF:0000033 GO_REF:0000117, RGD:1626621 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 enables IMP
ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:11532940), (PMID:19779139), (PMID:23878260), (PMID:9012504)
GO_REF:0000117
GO_REF:0000033
MGI:109124 (PMID:9247316)
UniProt
RGD
GO_Central
PMID:9012504 PMID:9247316 PMID:11532940 PMID:19779139 PMID:23878260 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000117, RGD:727326 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G Kdr kinase insert domain receptor enables IMP
ISO
IEA
IBA
(PMID:10022831), (PMID:10102632), (PMID:11387210), (PMID:1417831), (PMID:15215251)
GO_REF:0000117
GO_REF:0000033
(PMID:8356051)
RGD
UniProt
GO_Central
PMID:1417831 PMID:8356051 PMID:10022831 PMID:10102632 PMID:11387210 More... GO_REF:0000033 GO_REF:0000117, RGD:729081, RGD:1626621 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Nrp1 neuropilin 1 enables ISO
IEA
IBA
(MGI:5141569|PMID:21658587)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000118
RGD
InterPro
GO_Central
TreeGrafter
PMID:21658587 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 MGI:5141569 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nrp2 neuropilin 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha enables IEA
ISO
ISS
GO_REF:0000107
(PMID:17470632)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17470632 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a protein 2496
        protein kinase activity 621
          transmembrane receptor protein kinase activity 81
            transmembrane receptor protein tyrosine kinase activity 63
              vascular endothelial growth factor receptor activity 6
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      transferase activity 2428
        transferase activity, transferring phosphorus-containing groups 970
          kinase activity 802
            protein kinase activity 621
              protein tyrosine kinase activity 138
                transmembrane receptor protein tyrosine kinase activity 63
                  vascular endothelial growth factor receptor activity 6
paths to the root