ONTOLOGY REPORT - ANNOTATIONS
Term: vascular endothelial growth factor receptor activity
Accession: GO:0005021
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Definition: Combining with a vascular endothelial growth factor (VEGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms: exact_synonym: VEGF receptor activity; VEGF-activated receptor activity; VEGFR activity; vascular endothelial growth factor E-activated receptor activity; vascular endothelial growth factor-activated receptor activity
narrow_synonym: VEGF-A-activated receptor activity; VEGF-B-activated receptor activity; VEGF-C-activated receptor activity; VEGF-D-activated receptor activity; VEGF-E-activated receptor activity
alt_id: GO:0036326; GO:0036327; GO:0036328; GO:0036329; GO:0036330
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Flt1
Fms related receptor tyrosine kinase 1
enables
IMP ISO IEA IBA
(PMID:11312102), (PMID:1312256), (PMID:15952180), (PMID:8605350), (PMID:9299537) GO_REF:0000117 GO_REF:0000033 (PMID:8356051)
RGD UniProt GO_Central
PMID:1312256 PMID:8356051 PMID:8605350 PMID:9299537 PMID:11312102 PMID:15952180 PMID:15785231 More...
GO_REF:0000033 GO_REF:0000117, RGD:1626621
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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Flt4
Fms related receptor tyrosine kinase 4
enables
IMP ISS ISO IEA IBA
GO_REF:0000024 (PMID:11532940), (PMID:19779139), (PMID:23878260), (PMID:9012504) GO_REF:0000117 GO_REF:0000033 MGI:109124 (PMID:9247316)
UniProt RGD GO_Central
PMID:9012504 PMID:9247316 PMID:11532940 PMID:19779139 PMID:23878260 PMID:11683876 More...
GO_REF:0000024 GO_REF:0000033 GO_REF:0000117, RGD:727326
NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
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Kdr
kinase insert domain receptor
enables
IMP ISO IEA IBA
(PMID:10022831), (PMID:10102632), (PMID:11387210), (PMID:1417831), (PMID:15215251) GO_REF:0000117 GO_REF:0000033 (PMID:8356051)
RGD UniProt GO_Central
PMID:1417831 PMID:8356051 PMID:10022831 PMID:10102632 PMID:11387210 PMID:15215251 PMID:9442048 PMID:15785231 More...
GO_REF:0000033 GO_REF:0000117, RGD:729081 , RGD:1626621
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Nrp1
neuropilin 1
enables
ISO IEA IBA
(MGI:5141569|PMID:21658587) GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
RGD InterPro GO_Central TreeGrafter
PMID:21658587
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 MGI:5141569
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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Nrp2
neuropilin 2
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
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Pdgfra
platelet derived growth factor receptor alpha
enables
IEA ISO ISS
GO_REF:0000107 (PMID:17470632) GO_REF:0000024
Ensembl RGD UniProt
PMID:17470632
GO_REF:0000024 GO_REF:0000107
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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