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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet-derived growth factor receptor activity
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Accession:GO:0005017 term browser browse the term
Definition:Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: PDGF receptor activity;   PDGF-activated receptor activity;   PDGFR activity;   platelet-derived growth factor-activated receptor activity


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platelet-derived growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta enables TAS
ISO
IDA		 (PMID:26437238) RGD PMID:26437238 PMID:11557582 PMID:11903042 PMID:8318539 RGD:628442, RGD:1581762, RGD:633648 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
platelet-derived growth factor alpha-receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha enables IDA
ISO
IEA
IBA		 (PMID:10806482), (PMID:2536956), (PMID:2554309), (PMID:8188664)
GO_REF:0000107
(MGI:5294530|PMID:20110689)
GO_REF:0000118
GO_REF:0000033		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:2536956 PMID:2554309 PMID:8188664 PMID:10806482 PMID:20110689 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5294530, RGD:729439 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
platelet-derived growth factor beta-receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:1314164), (PMID:2536956), (PMID:2554309), (PMID:26599395), (PMID:2850496)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118		 UniProt
RGD
InterPro
Ensembl
GO_Central
TreeGrafter		 PMID:1314164 PMID:2536956 PMID:2554309 PMID:2850496 PMID:26599395 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      catalytic activity, acting on a protein 2516
        protein kinase activity 628
          transmembrane receptor protein kinase activity 81
            transmembrane receptor protein tyrosine kinase activity 63
              platelet-derived growth factor receptor activity 2
                platelet-derived growth factor alpha-receptor activity 1
                platelet-derived growth factor beta-receptor activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      transferase activity 2451
        transferase activity, transferring phosphorus-containing groups 983
          kinase activity 814
            protein kinase activity 628
              protein tyrosine kinase activity 138
                transmembrane receptor protein tyrosine kinase activity 63
                  platelet-derived growth factor receptor activity 2
                    platelet-derived growth factor alpha-receptor activity 1
                    platelet-derived growth factor beta-receptor activity 1
paths to the root