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ONTOLOGY REPORT - ANNOTATIONS

Term:fibroblast growth factor receptor activity
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Accession:GO:0005007 term browser browse the term
Definition:Combining with a fibroblast growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: FGF receptor activity;   FGF-activated receptor activity;   FGFR;   fibroblast growth factor-activated receptor activity


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fibroblast growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000066572 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:77,280,718...77,282,108 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 enables TAS
ISO
ISS
IEA
IBA		 (PMID:18480409), (PMID:20133753)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
(PMID:2161540)		 RGD
UniProt
InterPro
TreeGrafter
GO_Central		 PMID:2161540 PMID:18480409 PMID:20133753 PMID:9763444 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118, RGD:728839 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 enables TAS
IDA
ISO
IBA		 UniProtKB:P09038 (PMID:10830168), (PMID:15629145), (PMID:8663044)
GO_REF:0000033		 RGD
GO_Central		 PMID:8663044 PMID:10830168 PMID:15629145 PMID:7803853 PMID:15282342 GO_REF:0000033, RGD:632663, RGD:6480435 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 enables NAS
IDA
ISO
IBA		 (PMID:8663044)
GO_REF:0000033
(PMID:14699054)		 RGD
GO_Central		 PMID:8663044 PMID:14699054 PMID:11444149 PMID:15231666 GO_REF:0000033, RGD:632790, RGD:1304345 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 enables ISO
IEA
IBA		 UniProtKB:O95750 (PMID:10525310), (PMID:18480409), (PMID:21653700), (PMID:8663044)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118		 RGD
InterPro
Ensembl
GO_Central
TreeGrafter		 PMID:8663044 PMID:10525310 PMID:18480409 PMID:21653700 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 enables ISO
IEA
IBA		 (PMID:12813049)
(MGI:2673744|PMID:12813049)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:12813049 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:2673744 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      catalytic activity, acting on a protein 2516
        protein kinase activity 628
          transmembrane receptor protein kinase activity 81
            transmembrane receptor protein tyrosine kinase activity 63
              fibroblast growth factor receptor activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      transferase activity 2451
        transferase activity, transferring phosphorus-containing groups 983
          kinase activity 814
            protein kinase activity 628
              protein tyrosine kinase activity 138
                transmembrane receptor protein tyrosine kinase activity 63
                  fibroblast growth factor receptor activity 6
paths to the root