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ONTOLOGY REPORT - ANNOTATIONS

Term:AMPA glutamate receptor activity
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Accession:GO:0004971 term browser browse the term
Definition:An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.
Synonyms:exact_synonym: AMPA receptor activity;   alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity


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AMPA glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:54,634,332...54,710,711
Ensembl chr15:54,634,335...54,708,184 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:11834304 GO_REF:0000107 GO_REF:0000118 RGD:728843 NCBI chr  X:94,729,828...95,006,244
Ensembl chr  X:94,730,943...95,004,279 		JBrowse link
G GRIA4 glutamate ionotropic receptor AMPA type subunit 4 enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:2166337 GO_REF:0000107 GO_REF:0000118 RGD:728438 NCBI chr 5:26,272,008...26,642,819
Ensembl chr 5:26,272,970...26,642,100 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        inorganic molecular entity transmembrane transporter activity 694
          inorganic cation transmembrane transporter activity 580
            AMPA glutamate receptor activity 4
Path 2
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        passive transmembrane transporter activity 532
          channel activity 532
            gated channel activity 332
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 186
                  extracellular ligand-gated monoatomic ion channel activity 75
                    transmitter-gated monoatomic ion channel activity 64
                      glutamate-gated receptor activity 16
                        AMPA glutamate receptor activity 4
paths to the root