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ONTOLOGY REPORT - ANNOTATIONS

Term:AMPA glutamate receptor activity
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Accession:GO:0004971 term browser browse the term
Definition:An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.
Synonyms:exact_synonym: AMPA receptor activity;   alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity


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AMPA glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:11834304 GO_REF:0000107 GO_REF:0000118 RGD:728843 NCBI chr  X:112,380,229...112,687,740
Ensembl chr  X:122,562,330...122,870,130 		JBrowse link
G GRIA4 glutamate ionotropic receptor AMPA type subunit 4 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:2166337 GO_REF:0000107 GO_REF:0000118 RGD:728438 NCBI chr11:100,498,632...100,873,764
Ensembl chr11:103,983,862...104,355,280 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17460
    transporter activity 1150
      transmembrane transporter activity 1063
        inorganic molecular entity transmembrane transporter activity 637
          inorganic cation transmembrane transporter activity 528
            AMPA glutamate receptor activity 4
Path 2
Term Annotations click to browse term
  molecular_function 17460
    transporter activity 1150
      transmembrane transporter activity 1063
        passive transmembrane transporter activity 494
          channel activity 494
            gated channel activity 319
              ligand-gated channel activity 189
                ligand-gated monoatomic ion channel activity 185
                  extracellular ligand-gated monoatomic ion channel activity 74
                    transmitter-gated monoatomic ion channel activity 60
                      glutamate-gated receptor activity 16
                        AMPA glutamate receptor activity 4
paths to the root