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ONTOLOGY REPORT - ANNOTATIONS


Term:ionotropic glutamate receptor activity
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Accession:GO:0004970 term browser browse the term
Definition:Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'.


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ionotropic glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:4107730
RGD:1600115
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:728773
RGD:1600115
RGD:1624291
RGD:8553303
RGD:8553832
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 JBrowse link X 127,561,843 127,829,763 RGD:728843
RGD:1600115
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 JBrowse link 8 1,548,145 2,045,874 RGD:8554524
RGD:1600115
G Grid1 glutamate ionotropic receptor delta type subunit 1 JBrowse link 16 11,170,831 11,932,197 RGD:1600115
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1600115
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642466
RGD:1600115
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:69852
RGD:1600115
RGD:1624291
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1624291
RGD:8553493
RGD:8553521
G Grik4 glutamate ionotropic receptor kainate type subunit 4 JBrowse link 8 46,804,134 47,237,546 RGD:734533
RGD:1600115
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:727495
RGD:1642190
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1642190
RGD:2326036
RGD:2326029
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1642190
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:728651
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:728580
RGD:1624291
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A JBrowse link 5 64,928,620 65,073,012 RGD:632837
RGD:1600115
RGD:1642190
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B JBrowse link 7 12,764,993 12,771,310 RGD:1600115
AMPA glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:8554136
RGD:13792537
RGD:1624291
RGD:1600115
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:728773
RGD:13792537
RGD:8554236
RGD:8554136
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 JBrowse link X 127,561,843 127,829,763 RGD:728843
RGD:13792537
RGD:1624291
RGD:1600115
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 JBrowse link 8 1,548,145 2,045,874 RGD:728417
RGD:13792537
RGD:1624291
RGD:1600115
RGD:728438
glutamate-gated calcium ion channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:1600115
RGD:1624291
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1600115
RGD:1624291
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1600115
RGD:1624291
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:1600115
RGD:1624291
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:1600115
RGD:1624291
kainate selective glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:8553303
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642466
RGD:13792537
RGD:1624291
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:69852
RGD:13792537
RGD:1624291
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1600115
RGD:13792537
RGD:1624291
G Grik4 glutamate ionotropic receptor kainate type subunit 4 JBrowse link 8 46,804,134 47,237,546 RGD:734533
RGD:13792537
G Grik5 glutamate ionotropic receptor kainate type subunit 5 JBrowse link 1 81,885,516 81,946,731 RGD:625595
RGD:13792537
RGD:1624291
NMDA glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:727495
RGD:13792537
RGD:1624291
RGD:13432313
RGD:13432263
RGD:13432252
RGD:1600115
RGD:8553485
RGD:7241434
RGD:1642380
RGD:1642190
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:728651
RGD:13792537
RGD:1624291
RGD:13432313
RGD:13432339
RGD:1600115
RGD:7241434
RGD:1642380
RGD:1642190
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:727540
RGD:13792537
RGD:1624291
RGD:13432313
RGD:13432263
RGD:1600115
RGD:1642190
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:728651
RGD:13792537
RGD:1624291
RGD:1600115
RGD:1642375
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:728580
RGD:13792537
RGD:1624291
RGD:13432339
RGD:1600115
RGD:1642397
RGD:1642380
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A JBrowse link 5 64,928,620 65,073,012 RGD:632837
RGD:1624291
RGD:8553928
RGD:1642190
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8655534

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18263
    molecular transducer activity 2566
      signaling receptor activity 2526
        transmembrane signaling receptor activity 2354
          glutamate receptor activity 27
            ionotropic glutamate receptor activity 19
              AMPA glutamate receptor activity 4
              NMDA glutamate receptor activity 7
              glutamate-gated calcium ion channel activity 5
              kainate selective glutamate receptor activity 6
Path 2
Term Annotations click to browse term
  molecular_function 18263
    transporter activity 1190
      transmembrane transporter activity 1054
        passive transmembrane transporter activity 462
          channel activity 462
            gated channel activity 344
              ligand-gated channel activity 138
                ligand-gated ion channel activity 135
                  extracellular ligand-gated ion channel activity 70
                    transmitter-gated ion channel activity 58
                      ionotropic glutamate receptor activity 19
                        AMPA glutamate receptor activity 4
                        NMDA glutamate receptor activity 7
                        glutamate-gated calcium ion channel activity 5
                        kainate selective glutamate receptor activity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.