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ONTOLOGY REPORT - ANNOTATIONS

Term:GABA-A receptor activity
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Accession:GO:0004890 term browser browse the term
Definition:Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.
Synonyms:exact_synonym: ionotropic GABA receptor activity


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GABA-A receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 enables
contributes_to		 IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:49,006,981...49,065,205
Ensembl chr 4:49,009,495...49,062,581 		JBrowse link
G GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 enables
contributes_to		 IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:42,367,988...42,488,069
Ensembl chr13:42,368,949...42,488,075 		JBrowse link
G GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
Ensembl
GO_Central		 PMID:2153588 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:61593 NCBI chr  X:120,152,650...120,460,604
Ensembl chr  X:120,153,261...120,460,119 		JBrowse link
G GABRA4 gamma-aminobutyric acid type A receptor subunit alpha4 enables
contributes_to		 IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:42,889,100...42,958,604
Ensembl chr13:42,897,655...42,959,206 		JBrowse link
G GABRA5 gamma-aminobutyric acid type A receptor subunit alpha5 enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
Ensembl
GO_Central		 PMID:2153588 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:61593 NCBI chr 3:33,663,414...33,746,120
Ensembl chr 3:33,664,169...33,744,328 		JBrowse link
G GABRA6 gamma-aminobutyric acid type A receptor subunit alpha6 enables
contributes_to		 IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:49,208,691...49,225,754
Ensembl chr 4:49,208,605...49,226,212 		JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 enables ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:2548852 GO_REF:0000002 GO_REF:0000033 RGD:728451 NCBI chr13:43,011,491...43,349,876
Ensembl chr13:42,992,569...43,349,923 		JBrowse link
G GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 enables ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:11877425 GO_REF:0000002 GO_REF:0000033 RGD:727351 NCBI chr 4:49,342,527...49,579,697
Ensembl chr 4:49,342,508...49,578,092 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 enables ISO
IEA
IBA		 RGD
InterPro
GO_Central
Ensembl		 PMID:2548852 PMID:12356876 PMID:15152020 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1358699 RGD:727440 RGD:728451 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764 		JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta enables ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:12356876 GO_REF:0000002 GO_REF:0000033 RGD:727440 NCBI chr 5:56,984,786...56,994,790
Ensembl chr 5:56,984,913...56,994,358 		JBrowse link
G GABRE gamma-aminobutyric acid type A receptor subunit epsilon enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
Ensembl
GO_Central		 PMID:11691872 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:727328 NCBI chr  X:119,913,867...119,937,867
Ensembl chr  X:119,913,867...119,937,909 		JBrowse link
G GABRG1 gamma-aminobutyric acid type A receptor subunit gamma1 enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:2170110 GO_REF:0000002 GO_REF:0000033 RGD:728439 NCBI chr13:42,194,929...42,276,379
Ensembl chr13:42,200,202...42,276,711 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
Ensembl
GO_Central		 PMID:2561970 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:61596 NCBI chr 4:48,794,770...48,901,859
Ensembl chr 4:48,796,852...48,901,548 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 enables
contributes_to		 ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:1311098 GO_REF:0000002 GO_REF:0000033 RGD:727524 NCBI chr 3:32,956,061...33,641,971
Ensembl chr 3:32,964,122...33,642,686 		JBrowse link
G GABRP gamma-aminobutyric acid type A receptor subunit pi enables
contributes_to		 IEA
ISO
IBA		 InterPro
RGD
Ensembl
GO_Central		 PMID:9182563 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:728637 NCBI chr 4:41,164,725...41,186,716
Ensembl chr 4:41,166,453...41,184,589 		JBrowse link
G GABRQ gamma-aminobutyric acid type A receptor subunit theta enables IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:120,607,815...120,630,251
Ensembl chr  X:120,607,686...120,628,343 		JBrowse link
G GABRR1 gamma-aminobutyric acid type A receptor subunit rho1 enables IEA
IBA		 Ensembl
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:48,431,273...48,465,426
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GABRR2 gamma-aminobutyric acid type A receptor subunit rho2 enables ISO
IEA
IBA		 RGD
InterPro
Ensembl
GO_Central		 PMID:11891787 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:728465 NCBI chr12:48,492,607...48,537,961
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GABRR3 gamma-aminobutyric acid type A receptor rho3 subunit enables ISO PMID:11861315 UniProt PMID:11861315 RGD:405650323 NCBI chr33:5,013,983...5,036,304 JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21958
    molecular transducer activity 1885
      signaling receptor activity 1885
        transmembrane signaling receptor activity 1684
          GABA receptor activity 23
            GABA-A receptor activity 19
paths to the root