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ONTOLOGY REPORT - ANNOTATIONS

Term:GABA-A receptor activity
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Accession:GO:0004890 term browser browse the term
Definition:Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.
Synonyms:exact_synonym: ionotropic GABA receptor activity


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GABA-A receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 enables TAS
IDA
ISO
IEA		 PMID:9882711
(PMID:23909897), (PMID:30602789)
GO_REF:0000107		 RGD
Ensembl		 PMID:23909897 PMID:30602789 PMID:11161482 PMID:9882711 GO_REF:0000107, RGD:625528, RGD:405650244 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 enables
contributes_to		 TAS
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:11161482 GO_REF:0000002 GO_REF:0000033, RGD:625528 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 enables IDA
TAS
ISO
IEA		 (PMID:16412217)
PMID:9882711
GO_REF:0000107		 RGD
Ensembl		 PMID:16412217 PMID:2153588 PMID:11161482 PMID:9882711 GO_REF:0000107, RGD:61593, RGD:625528, RGD:405650244 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 contributes_to TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12581182 GO_REF:0000033, RGD:1299322 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 enables IDA
ISO		 PMID:10462548
(PMID:14993607)		 RGD PMID:14993607 PMID:2153588 PMID:10462548 RGD:61593, RGD:405650343 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 contributes_to
enables		 IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:17395622 GO_REF:0000002 GO_REF:0000033, RGD:1626515 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 enables IDA
IMP
ISO
IBA		 PMID:2540033
(PMID:16412217)
GO_REF:0000033		 RGD
GO_Central		 PMID:16412217 PMID:2548852 PMID:2540033 GO_REF:0000033, RGD:728451, RGD:8693372 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 enables TAS
IMP
IEA
IBA		 PMID:18281286
GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:11161482 PMID:11877425 PMID:18281286 GO_REF:0000002 GO_REF:0000033, RGD:625528, RGD:727351, RGD:8693370 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 enables TAS
IDA
IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000107
PMID:10462548
(PMID:14993607), (PMID:22303015), (PMID:30602789)
(PMID:9108119)
GO_REF:0000033		 InterPro
Ensembl
RGD
GO_Central		 PMID:9108119 PMID:14993607 PMID:22303015 PMID:30602789 PMID:11161482 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:625528, RGD:728451, RGD:727440, RGD:1358699, RGD:405650343 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:12356876 GO_REF:0000002 GO_REF:0000033, RGD:727440 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411 		JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon enables IDA
IEA
ISO		 GO_REF:0000002
(PMID:16412217), (PMID:9882711)		 InterPro
RGD		 PMID:9882711 PMID:16412217 PMID:11691872 GO_REF:0000002, RGD:727328 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 enables IDA
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:2170110 GO_REF:0000002, RGD:728439 NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 enables IDA
TAS
IEA
ISO		 GO_REF:0000107
(PMID:30602789)
(PMID:14993607)
(PMID:12574411), (PMID:18281286)		 Ensembl
RGD		 PMID:12574411 PMID:14993607 PMID:18281286 PMID:30602789 PMID:2561970 More... GO_REF:0000107, RGD:61596, RGD:625528 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 enables IDA
IEA		 GO_REF:0000002
PMID:10462548		 InterPro
RGD		 PMID:1311098 PMID:10462548 GO_REF:0000002, RGD:727524, RGD:405650343 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763 		JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi contributes_to
enables		 IDA
ISO
IMP
IEA
IBA		 (PMID:10462548)
PMID:17003036
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10462548 PMID:9182563 PMID:17003036 GO_REF:0000033 GO_REF:0000107, RGD:728637, RGD:405650305 NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516 		JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta enables ISO
IBA		 (PMID:16412217)
GO_REF:0000033		 RGD
GO_Central		 PMID:16412217 GO_REF:0000033 NCBI chr  X:150,696,161...150,712,948
Ensembl chr  X:150,696,427...150,709,919 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 enables IEA
IDA
IBA		 GO_REF:0000002
PMID:8524843
GO_REF:0000033		 InterPro
GO_Central		 PMID:8524843 GO_REF:0000002 GO_REF:0000033, RGD:728796 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 enables IDA
ISO
IBA		 MGI:2446461 (PMID:12019334)
PMID:8524843
GO_REF:0000033		 RGD
GO_Central		 PMID:12019334 PMID:11891787 PMID:8524843 GO_REF:0000033, RGD:728465, RGD:728796 NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809 		JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 enables IDA
IBA		 PMID:11861315
GO_REF:0000033		 GO_Central PMID:11861315 GO_REF:0000033, RGD:405650323 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    molecular transducer activity 2665
      signaling receptor activity 2665
        transmembrane signaling receptor activity 2416
          GABA receptor activity 23
            GABA-A receptor activity 19
paths to the root