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ONTOLOGY REPORT - ANNOTATIONS

Term:valine-tRNA ligase activity
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Accession:GO:0004832 term browser browse the term
Definition:Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H+.
Synonyms:exact_synonym: valyl-tRNA synthetase activity
 related_synonym: L-valine:tRNAVal ligase (AMP-forming);   valine transfer ribonucleate ligase activity;   valine translase activity;   valyl-transfer RNA synthetase activity;   valyl-transfer ribonucleate synthetase activity;   valyl-transfer ribonucleic acid synthetase activity
 xref: EC:6.1.1.9;   KEGG_REACTION:R03665;   MetaCyc:VALINE--TRNA-LIGASE-RXN;   RHEA:10704;   reactome:R-HSA-380042 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate";   reactome:R-HSA-380199 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate"


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valine-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vars1 valyl-tRNA synthetase 1 enables IDA
ISO
IEA
IBA		 (PMID:8428657)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000118		 RGD
InterPro
GO_Central
TreeGrafter		 PMID:8428657 PMID:8428657 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118, RGD:634466 NCBI chr20:3,805,774...3,820,468
Ensembl chr20:3,805,776...3,820,298 		JBrowse link
G Vars2 valyl-tRNA synthetase 2, mitochondrial enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:24827421)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:24827421 GO_REF:0000024 GO_REF:0000033 NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      ligase activity 183
        ligase activity, forming carbon-oxygen bonds 45
          aminoacyl-tRNA ligase activity 45
            valine-tRNA ligase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      catalytic activity, acting on a nucleic acid 642
        catalytic activity, acting on RNA 403
          catalytic activity, acting on a tRNA 138
            aminoacyl-tRNA ligase activity 45
              valine-tRNA ligase activity 2
paths to the root