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ONTOLOGY REPORT - ANNOTATIONS
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Term:
thromboxane-A synthase activity
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Accession:
GO:0004796
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Definition:
Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).
Synonyms:
narrow_synonym:
cytochrome P450 CYP5
related_synonym:
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity; (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity; thromboxane synthase activity; thromboxane synthetase activity
alt_id:
GO:0008400
xref:
EC:5.3.99.5; KEGG_REACTION:R02268; MetaCyc:THROMBOXANE-A-SYNTHASE-RXN; RHEA:17137; Reactome:R-HSA-5603275 "Defective TBXAS1 does not isomerise PGH2 to TXA2"; reactome:R-HSA-76500 "TBXAS1 isomerises PGH2 to TXA2"
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Rat (2)
Mouse (2)
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Bonobo (2)
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Pig (2)
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All
Genes (2)
thromboxane-A synthase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
enables
ISO
(PMID:21068195)
RGD
PMID:21068195
NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
G
Tbxas1
thromboxane A synthase 1
enables
ISO
IBA
(PMID:11097184), (PMID:11297515)
GO_REF:0000033
(PMID:7688225)
RGD
GO_Central
PMID:7688225
PMID:11097184
PMID:11297515
GO_REF:0000033
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
Term paths to the root
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Path 1
Term
Annotations
molecular_function
20732
catalytic activity
6109
isomerase activity
212
intramolecular oxidoreductase activity
71
thromboxane-A synthase activity
2