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ONTOLOGY REPORT - ANNOTATIONS

Term:ribose phosphate diphosphokinase activity
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Accession:GO:0004749 term browser browse the term
Definition:Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H+.
Comment:Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
Synonyms:exact_synonym: ribose-phosphate pyrophosphokinase activity
 related_synonym: 5-phosphoribose pyrophosphorylase activity;   5-phosphoribosyl-1-pyrophosphate synthetase activity;   5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity;   ATP:D-ribose-5-phosphate diphosphotransferase activity;   PP-ribose P synthetase activity;   PPRibP synthetase activity;   PRPP synthetase activity;   phosphoribosyl diphosphate synthetase activity;   phosphoribosyl pyrophosphate synthetase activity;   phosphoribosylpyrophosphate synthase activity;   phosphoribosylpyrophosphate synthetase activity;   pyrophosphoribosylphosphate synthetase activity;   ribophosphate pyrophosphokinase activity;   ribose-5-phosphate pyrophosphokinase activity
 xref: EC:2.7.6.1;   KEGG_REACTION:R01049;   MetaCyc:PRPPSYN-RXN;   RHEA:15609;   reactome:R-HSA-111215 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate";   reactome:R-HSA-73580 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate"


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ribose phosphate diphosphokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000063771 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 8:29,989,298...29,991,027 JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 enables IDA
ISO
ISS
IBA		 (PMID:12847698), (PMID:16939420), (PMID:17701896), (PMID:17701900)
GO_REF:0000024
GO_REF:0000033
(PMID:26175007)		 RGD
UniProt
GO_Central		 PMID:12847698 PMID:16939420 PMID:17701896 PMID:17701900 PMID:26175007 More... GO_REF:0000024 GO_REF:0000033, RGD:5134985, RGD:1599724, RGD:2291920, RGD:2291928 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:57,412,331...57,414,021
Ensembl chr 6:51,684,948...51,687,291 		JBrowse link
G Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 enables ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:74,755,331...74,763,493
Ensembl chr 6:74,755,310...74,766,465 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 enables IDA
ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:24855946), (PMID:26175007)		 UniProt
Ensembl
GO_Central
RGD		 PMID:24855946 PMID:26175007 PMID:2546925 PMID:9748490 PMID:1651917 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:5134985, RGD:1599724, RGD:2291920, RGD:2291928 NCBI chr  X:26,975,915...27,013,184
Ensembl chr  X:26,976,061...27,013,181 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      transferase activity 2443
        transferase activity, transferring phosphorus-containing groups 1008
          diphosphotransferase activity 6
            ribose phosphate diphosphokinase activity 5
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