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ONTOLOGY REPORT - ANNOTATIONS


Term:pyruvate dehydrogenase (acetyl-transferring) kinase activity
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Accession:GO:0004740 term browser browse the term
Definition:Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.
Synonyms:exact_synonym: ATP:pyruvate dehydrogenase (acetyl-transferring) phosphotransferase activity;   PDH kinase activity;   pyruvate dehydrogenase (lipoamide) kinase activity;   pyruvate dehydrogenase kinase (phosphorylating) activity;   pyruvate dehydrogenase kinase activity
 narrow_synonym: pyruvate dehydrogenase kinase activator protein activity
 related_synonym: PDHK;   PDK;   PDK1;   PDK2;   PDK3;   PDK4;   STK1
 xref: EC:2.7.11.2;   MetaCyc:2.7.11.2-RXN;   reactome:R-HSA-203946 "PDK isoforms phosphorylate lipo-PDH"


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pyruvate dehydrogenase (acetyl-transferring) kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:68684
RGD:1624291
RGD:1600115
RGD:8553418
RGD:68199
RGD:2307429
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1582376
RGD:1624291
RGD:1582377
RGD:2307429
RGD:68199
RGD:8553418
RGD:1600115
G Pdk3 pyruvate dehydrogenase kinase 3 JBrowse link X 62,836,131 62,904,114 RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:729541
RGD:8553418
RGD:68199
RGD:1582377
RGD:1582376

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18263
    catalytic activity 5790
      catalytic activity, acting on a protein 2204
        protein kinase activity 610
          pyruvate dehydrogenase (acetyl-transferring) kinase activity 4
Path 2
Term Annotations click to browse term
  molecular_function 18263
    catalytic activity 5790
      transferase activity 2294
        transferase activity, transferring phosphorus-containing groups 960
          kinase activity 810
            protein kinase activity 610
              pyruvate dehydrogenase (acetyl-transferring) kinase activity 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.