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ONTOLOGY REPORT - ANNOTATIONS

Term:protein serine/threonine phosphatase activity
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Accession:GO:0004722 term browser browse the term
Definition:Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
Synonyms:exact_synonym: serine/threonine specific protein phosphatase activity
 narrow_synonym: phosphatase I;   phosphatase II;   phosphatase III;   protein phosphatase type 1 activity;   protein phosphatase type 2A activity;   protein phosphatase type 2B activity;   protein phosphatase type 2C activity;   protein phosphatase-1;   protein phosphatase-2A;   protein phosphatase-2B;   protein phosphatase-2C;   protein serine phosphatase activity;   protein threonine phosphatase activity
 related_synonym: magnesium-dependent protein serine/threonine phosphatase activity
 alt_id: GO:0000158;   GO:0000163;   GO:0004724;   GO:0008598;   GO:0008600;   GO:0015071;   GO:0030357;   GO:0030358;   GO:0030360;   GO:0030361;   GO:0106306;   GO:0106307
 xref: EC:3.1.3.16;   MetaCyc:3.1.3.16-RXN;   Reactome:R-HSA-163689 "Dephosphorylation of pChREBP (Ser 196) by PP2A";   Reactome:R-HSA-163750 "Dephosphorylation of phosphoPFKFB1 by PP2A complex";   Reactome:R-HSA-429730 "PPM1L dephosphorylates multiphospho-CERT1-2";   Reactome:R-HSA-9658445 "MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs";   Reactome:R-HSA-9660536 "SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex";   Reactome:R-HSA-9660538 "Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs";   Reactome:R-HSA-9686524 "PP6-PPP6R3 dephosphorylates TERF2";   Reactome:R-HSA-9831948 "P:PP1 dephosphorylates M2-1";   Reactome:R-HSA-9853385 "PPP1CC dephosphorylates PLK1";   Reactome:R-HSA-9861725 "PGAM5 dodecamer dephosphorylates p-S336-ME1";   reactome:R-HSA-1295632 "PPA2A dephosphorylates SPRY2";   reactome:R-HSA-163568 "phosphorylated perilipin + H2O -> perilipin + orthophosphate";   reactome:R-HSA-1638821 "PP2A-B56 dephosphorylates centromeric cohesin";   reactome:R-HSA-199425 "PHLPP dephosphorylates S473 in AKT";   reactome:R-HSA-199959 "ERKs are inactivated by protein phosphatase 2A";   reactome:R-HSA-201787 "PPP3 complex dephosphorylates DARPP-32 on Thr34";   reactome:R-HSA-201790 "DARPP-32 is dephosphorylated on Thr75 by PP2A";   reactome:R-HSA-209055 "PPM1A dephosphorylates nuclear SMAD2/3";   reactome:R-HSA-2187401 "MTMR4 dephosphorylates SMAD2/3";   reactome:R-HSA-2995388 "PP2A dephosphorylates BANF1";   reactome:R-HSA-3002811 "Myosin phosphatase dephosphorylates PLK1";   reactome:R-HSA-3601585 "PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex";   reactome:R-HSA-380949 "AMPK is dephosphorylated";   reactome:R-HSA-4088141 "PP2A-PPP2R2A dephosphorylates FOXM1";   reactome:R-HSA-4419948 "CTDNEP1:CNEP1R1 dephosphorylates LPIN";   reactome:R-HSA-5672957 "PP2A dephosphorylates KSR1";   reactome:R-HSA-5672961 "PP2A dephosphorylates inactive RAFs";   reactome:R-HSA-5675431 "PP2A dephosphorylates RAF1";   reactome:R-HSA-5675433 "PP5 dephosphorylates RAF1 S338";   reactome:R-HSA-5679206 "MTMR14, MTMR3 dephosphorylate PI3P";   reactome:R-HSA-5683405 "PPP5C dephosphorylates TP53BP1";   reactome:R-HSA-5687758 "PPP4C:PPP4R2 dephosphorylates RPA2";   reactome:R-HSA-5692754 "CDC14A,B dephosphorylate p-3S,T MAPK6";   reactome:R-HSA-5693153 "PPM1K dephosphorylates p-BCKDH";   reactome:R-HSA-5694421 "PP6 dephosphorylates SEC24";   reactome:R-HSA-6792863 "PP2A-PP2R5C dephosphorylates MDM2";   reactome:R-HSA-6811504 "AKT1 dephosphorylation by PP2A-B56-beta,gamma";   reactome:R-HSA-74948 "PP2A dephosphorylates p-RHO to RHO";   reactome:R-HSA-8948139 "p-S13-FUNDC1 is dephosphorylated by PGAM5";   reactome:R-HSA-9619430 "PPM1E dephosphorylates CAMK4";   reactome:R-HSA-9619449 "PPM1F dephosphorylates p-T286-CaMKII";   reactome:R-HSA-9619467 "PPM1F dephosphorylates CAMK1"


show annotations for term's descendants           Sort by:
protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC013717.1 novel protein, PPM1B-SLC3A1 readthrough enables IEA InterPro GO_REF:0000002 Ensembl chr 2:44,168,851...44,320,310 JBrowse link
G AC120057.2 novel protein enables IEA UniProt GO_REF:0000117 Ensembl chr17:7,240,427...7,244,635 JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase enables IDA (PMID:29779826) UniProt PMID:29779826 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G CDC14A cell division cycle 14A enables TAS
IBA
IEA		 Reactome
GO_Central
TreeGrafter
RHEA		 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 Reactome:R-HSA-5692754 NCBI chr 1:100,345,001...100,520,277
Ensembl chr 1:100,345,001...100,520,277 		JBrowse link
G CDC14B cell division cycle 14B enables TAS
IEA
IBA
IDA		 (PMID:18662541), (PMID:9367992) Reactome
TreeGrafter
GO_Central
RHEA
UniProt		 PMID:9367992 PMID:18662541 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 Reactome:R-HSA-5692754 NCBI chr 9:96,490,939...96,619,843
Ensembl chr 9:96,490,241...96,619,843 		JBrowse link
G CDC14C cell division cycle 14C enables IEA
IBA		 RHEA
GO_Central		 GO_REF:0000033 GO_REF:0000116 NCBI chr 7:48,924,547...48,927,454
Ensembl chr 7:48,924,547...48,927,454 		JBrowse link
G CDKL3 cyclin dependent kinase like 3 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 5:134,283,345...134,371,624
Ensembl chr 5:134,286,350...134,371,047 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 enables IDA
IEA		 (PMID:12745075) MGI
RHEA		 PMID:12745075 GO_REF:0000116 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CPPED1 calcineurin like phosphoesterase domain containing 1 enables IEA RHEA GO_REF:0000116 NCBI chr16:12,659,799...12,803,887
Ensembl chr16:12,659,799...12,803,887 		JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 enables IMP
IBA
IEA
TAS		 (PMID:17420445) UniProt
GO_Central
RHEA
Reactome		 PMID:17420445 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117 Reactome:R-HSA-4419948 NCBI chr17:7,243,591...7,251,978
Ensembl chr17:7,243,591...7,252,491 		JBrowse link
G CTDP1 CTD phosphatase subunit 1 enables IEA UniProt
RHEA		 GO_REF:0000116 GO_REF:0000117 NCBI chr18:79,676,768...79,756,625
Ensembl chr18:79,679,803...79,754,503 		JBrowse link
G CTDSP1 CTD small phosphatase 1 enables IEA RHEA
UniProt		 GO_REF:0000116 GO_REF:0000117 NCBI chr 2:218,396,351...218,405,941
Ensembl chr 2:218,397,136...218,405,941 		JBrowse link
G CTDSP2 CTD small phosphatase 2 enables IEA RHEA
UniProt		 GO_REF:0000116 GO_REF:0000117 NCBI chr12:57,819,927...57,846,729
Ensembl chr12:57,819,927...57,846,729 		JBrowse link
G CTDSPL CTD small phosphatase like enables IEA UniProt
RHEA		 GO_REF:0000116 GO_REF:0000117 NCBI chr 3:37,861,880...37,984,469
Ensembl chr 3:37,861,880...37,984,469 		JBrowse link
G CTDSPL2 CTD small phosphatase like 2 enables IEA UniProt GO_REF:0000117 NCBI chr15:44,427,629...44,529,038
Ensembl chr15:44,427,622...44,529,038 		JBrowse link
G DUSP1 dual specificity phosphatase 1 enables IEA
ISS		 Ensembl
RHEA
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP10 dual specificity phosphatase 10 enables IEA RHEA GO_REF:0000116 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G DUSP12 dual specificity phosphatase 12 enables IEA RHEA GO_REF:0000116 NCBI chr 1:161,749,786...161,757,238
Ensembl chr 1:161,749,758...161,757,238 		JBrowse link
G DUSP13A dual specificity phosphatase 13A enables IEA RHEA GO_REF:0000116 NCBI chr10:75,105,669...75,109,157
Ensembl chr10:75,094,434...75,109,221 		JBrowse link
G DUSP13B dual specificity phosphatase 13B enables IEA RHEA GO_REF:0000116 NCBI chr10:75,094,434...75,109,191
Ensembl chr10:75,094,432...75,109,206
Ensembl chr10:75,094,432...75,109,206 		JBrowse link
G DUSP14 dual specificity phosphatase 14 enables IEA RHEA GO_REF:0000116 NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501 		JBrowse link
G DUSP15 dual specificity phosphatase 15 enables IEA RHEA GO_REF:0000116 NCBI chr20:31,845,593...31,870,664
Ensembl chr20:31,847,637...31,870,664 		JBrowse link
G DUSP16 dual specificity phosphatase 16 enables IEA RHEA GO_REF:0000116 NCBI chr12:12,473,282...12,562,863
Ensembl chr12:12,473,282...12,562,863 		JBrowse link
G DUSP18 dual specificity phosphatase 18 enables IEA RHEA GO_REF:0000116 NCBI chr22:30,652,051...30,667,875
Ensembl chr22:30,652,051...30,667,887 		JBrowse link
G DUSP19 dual specificity phosphatase 19 enables IEA RHEA GO_REF:0000116 NCBI chr 2:183,078,747...183,100,008
Ensembl chr 2:183,078,559...183,100,008 		JBrowse link
G DUSP2 dual specificity phosphatase 2 enables IEA RHEA GO_REF:0000116 NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,169...96,145,440 		JBrowse link
G DUSP21 dual specificity phosphatase 21 enables IEA RHEA GO_REF:0000116 NCBI chr  X:44,844,021...44,844,888
Ensembl chr  X:44,844,021...44,844,888 		JBrowse link
G DUSP22 dual specificity phosphatase 22 enables IEA RHEA GO_REF:0000116 NCBI chr 6:292,487...351,355
Ensembl chr 6:291,630...351,355 		JBrowse link
G DUSP23 dual specificity phosphatase 23 enables IEA RHEA GO_REF:0000116 NCBI chr 1:159,780,962...159,782,543
Ensembl chr 1:159,780,932...159,782,543 		JBrowse link
G DUSP26 dual specificity phosphatase 26 enables IEA RHEA GO_REF:0000116 NCBI chr 8:33,591,330...33,600,023
Ensembl chr 8:33,591,330...33,600,023 		JBrowse link
G DUSP28 dual specificity phosphatase 28 enables IEA RHEA GO_REF:0000116 NCBI chr 2:240,560,054...240,565,256
Ensembl chr 2:240,560,054...240,565,256 		JBrowse link
G DUSP29 dual specificity phosphatase 29 enables IEA RHEA GO_REF:0000116 NCBI chr10:75,037,472...75,073,642
Ensembl chr10:75,037,472...75,073,642 		JBrowse link
G DUSP3 dual specificity phosphatase 3 enables IEA RHEA GO_REF:0000116 NCBI chr17:43,766,125...43,778,977
Ensembl chr17:43,766,125...43,778,977 		JBrowse link
G DUSP4 dual specificity phosphatase 4 enables IEA RHEA GO_REF:0000116 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G DUSP5 dual specificity phosphatase 5 enables IEA RHEA GO_REF:0000116 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP6 dual specificity phosphatase 6 enables IEA RHEA GO_REF:0000116 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G DUSP7 dual specificity phosphatase 7 enables IEA RHEA GO_REF:0000116 NCBI chr 3:52,048,919...52,056,571
Ensembl chr 3:52,048,919...52,056,571 		JBrowse link
G DUSP8 dual specificity phosphatase 8 enables IEA RHEA GO_REF:0000116 NCBI chr11:1,554,051...1,572,848
Ensembl chr11:1,554,051...1,572,271 		JBrowse link
G DUSP9 dual specificity phosphatase 9 enables IEA RHEA GO_REF:0000116 NCBI chr  X:153,642,441...153,651,326
Ensembl chr  X:153,642,492...153,651,326 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin enables IEA
IDA		 (PMID:12915448) Ensembl
RHEA
UniProt		 PMID:12915448 GO_REF:0000107 GO_REF:0000116 NCBI chr 6:145,383,353...145,736,023
Ensembl chr 6:145,382,535...145,736,023 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 enables IEA RHEA GO_REF:0000116 NCBI chr 8:71,197,433...71,548,094
Ensembl chr 8:71,197,433...71,592,025 		JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase enables IEA RHEA GO_REF:0000116 NCBI chr 6:109,691,296...109,825,426
Ensembl chr 6:109,690,609...109,878,098 		JBrowse link
G ILKAP ILK associated serine/threonine phosphatase enables ISO
IEA		 RGD
InterPro
RHEA		 PMID:9857069 GO_REF:0000002 GO_REF:0000116 RGD:632254 NCBI chr 2:238,170,402...238,203,695
Ensembl chr 2:238,170,402...238,203,708 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase enables IDA (PMID:8506364) UniProt PMID:8506364 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G LOC124907782 dual specificity protein phosphatase 22 enables IEA RHEA GO_REF:0000116
G LRRC18 leucine rich repeat containing 18 enables IBA GO_Central GO_REF:0000033 NCBI chr10:48,909,480...48,939,840
Ensembl chr10:48,909,480...48,939,840 		JBrowse link
G LRRC59 leucine rich repeat containing 59 enables IBA GO_Central GO_REF:0000033 NCBI chr17:50,381,238...50,397,523
Ensembl chr17:50,375,059...50,397,523 		JBrowse link
G MTMR14 myotubularin related protein 14 enables TAS Reactome Reactome:R-HSA-5679206 NCBI chr 3:9,649,505...9,702,393
Ensembl chr 3:9,649,433...9,702,393 		JBrowse link
G MTMR3 myotubularin related protein 3 enables TAS
IDA		 (PMID:10733931) Reactome
UniProt		 PMID:10733931 Reactome:R-HSA-5679206 NCBI chr22:29,883,174...30,030,868
Ensembl chr22:29,883,169...30,030,868 		JBrowse link
G MTMR4 myotubularin related protein 4 enables TAS
IDA		 (PMID:23150675) Reactome
FlyBase		 PMID:23150675 Reactome:R-HSA-2187401 NCBI chr17:58,489,537...58,519,047
Ensembl chr17:58,489,529...58,517,905 		JBrowse link
G MTMR6 myotubularin related protein 6 enables NAS (PMID:9736772) UniProt PMID:9736772 NCBI chr13:25,246,222...25,287,488
Ensembl chr13:25,246,222...25,287,510 		JBrowse link
G PDP1 pyruvate dehydrogenase phosphatase catalytic subunit 1 enables ISO
IEA
IDA		 (PMID:20801214) RGD
InterPro
UniProt		 PMID:15210124 PMID:20801214 GO_REF:0000002 RGD:1642641 NCBI chr 8:93,916,923...93,926,068
Ensembl chr 8:93,857,807...93,926,068 		JBrowse link
G PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 enables IEA InterPro GO_REF:0000002 NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754 		JBrowse link
G PDXP pyridoxal phosphatase enables IEA RHEA GO_REF:0000116 NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932 		JBrowse link
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase enables IDA
IBA
IEA
TAS		 (PMID:19590015) CACAO
GO_Central
RHEA
Reactome		 PMID:19590015 GO_REF:0000033 GO_REF:0000116 Reactome:R-HSA-8948139 NCBI chr12:132,710,842...132,722,734
Ensembl chr12:132,710,819...132,722,734 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 enables ISO
IDA
IBA
IEA		 (PMID:28147277) RGD
UniProt
GO_Central
RHEA		 PMID:20089132 PMID:28147277 GO_REF:0000033 GO_REF:0000116 RGD:5131540 NCBI chr18:62,715,541...62,980,433
Ensembl chr18:62,715,541...62,980,433 		JBrowse link
G PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 enables ISO
IBA
IEA		 RGD
GO_Central
RHEA
Ensembl		 PMID:20089132 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 RGD:5131540 NCBI chr16:71,644,924...71,724,701
Ensembl chr16:71,637,835...71,724,701 		JBrowse link
G PP2D1 protein phosphatase 2C like domain containing 1 enables IEA InterPro GO_REF:0000002 NCBI chr 3:19,979,961...20,012,264
Ensembl chr 3:19,979,961...20,012,267 		JBrowse link
G PPA2 inorganic pyrophosphatase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:105,369,077...105,474,070
Ensembl chr 4:105,369,077...105,474,067 		JBrowse link
G PPEF1 protein phosphatase with EF-hand domain 1 enables TAS
IBA
IEA		 (PMID:9215685) PINC
GO_Central
RHEA		 PMID:9215685 GO_REF:0000033 GO_REF:0000116 NCBI chr  X:18,675,067...18,827,917
Ensembl chr  X:18,675,909...18,827,921 		JBrowse link
G PPEF2 protein phosphatase with EF-hand domain 2 enables TAS
IBA
IEA		 (PMID:9326663) PINC
GO_Central
RHEA		 PMID:9326663 GO_REF:0000033 GO_REF:0000116 NCBI chr 4:75,859,867...75,902,452
Ensembl chr 4:75,859,864...75,902,571 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A enables TAS
IEA
IBA
IDA		 (PMID:1311954)
(PMID:10644691), (PMID:11559703), (PMID:20801214)		 Reactome
TreeGrafter
GO_Central
InterPro
RHEA
UniProt		 PMID:1311954 PMID:10644691 PMID:11559703 PMID:20801214 GO_REF:0000002 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 Reactome:R-HSA-209055 Reactome:R-HSA-380949 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B enables IDA
IEA
IBA
TAS		 (PMID:20801214)
(PMID:9684878)		 UniProt
TreeGrafter
GO_Central
InterPro
RHEA
PINC		 PMID:9684878 PMID:20801214 GO_REF:0000002 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 NCBI chr 2:44,168,875...44,246,928
Ensembl chr 2:44,167,969...44,244,384 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D enables IDA
IEA
IBA
TAS		 (PMID:20801214)
(PMID:9177166)		 UniProt
TreeGrafter
GO_Central
InterPro
RHEA
PINC		 PMID:9177166 PMID:20801214 GO_REF:0000002 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280 		JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E enables ISO
IEA
IDA		 (PMID:20801214) RGD
InterPro
RHEA
UniProt
Ensembl		 PMID:12807427 PMID:20801214 GO_REF:0000002 GO_REF:0000107 GO_REF:0000116 RGD:1299619 NCBI chr17:58,755,854...58,985,179
Ensembl chr17:58,755,854...58,985,179 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F enables ISO
IEA
IMP
IDA		 (PMID:20016286)
(PMID:11559703), (PMID:11864573), (PMID:15140879), (PMID:20801214)		 RGD
InterPro
RHEA
UniProt
Ensembl		 PMID:10456318 PMID:11559703 PMID:11864573 PMID:15140879 PMID:20016286 More... GO_REF:0000002 GO_REF:0000107 GO_REF:0000116 RGD:7241145 NCBI chr22:21,919,425...21,952,848
Ensembl chr22:21,919,425...21,952,848 		JBrowse link
G PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G enables IDA
IEA
TAS		 (PMID:20801214)
(PMID:9276438)		 UniProt
InterPro
RHEA
PINC		 PMID:9276438 PMID:20801214 GO_REF:0000002 GO_REF:0000116 NCBI chr 2:27,381,199...27,409,591
Ensembl chr 2:27,381,195...27,409,591 		JBrowse link
G PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H enables IEA RHEA
InterPro		 GO_REF:0000002 GO_REF:0000116 NCBI chr12:62,643,994...62,935,150
Ensembl chr12:62,643,994...62,935,150 		JBrowse link
G PPM1J protein phosphatase, Mg2+/Mn2+ dependent 1J enables IEA Ensembl
InterPro
RHEA		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000116 NCBI chr 1:112,709,998...112,715,332
Ensembl chr 1:112,709,994...112,715,332 		JBrowse link
G PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K enables IEA
IBA
IDA		 (PMID:17374715), (PMID:22291014), (PMID:29779826) InterPro
GO_Central
RHEA
UniProt		 PMID:17374715 PMID:22291014 PMID:29779826 GO_REF:0000002 GO_REF:0000033 GO_REF:0000116 NCBI chr 4:88,257,620...88,284,561
Ensembl chr 4:88,257,620...88,284,769 		JBrowse link
G PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L enables TAS
IEA		 Reactome
InterPro
RHEA
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000116 Reactome:R-HSA-429730 NCBI chr 3:160,756,231...161,078,902
Ensembl chr 3:160,755,602...161,078,902 		JBrowse link
G PPM1M protein phosphatase, Mg2+/Mn2+ dependent 1M enables IEA RHEA
InterPro		 GO_REF:0000002 GO_REF:0000116 NCBI chr 3:52,245,759...52,250,599
Ensembl chr 3:52,245,759...52,250,599 		JBrowse link
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) enables IEA
IBA		 RHEA
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000116 NCBI chr19:45,498,443...45,502,513
Ensembl chr19:45,488,777...45,502,513 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha enables TAS
IBA
IDA
IEA		 (PMID:10640627), (PMID:16262633), (PMID:8392016)
(PMID:28216226)		 ARUK-UCL
GO_Central
UniProt
TreeGrafter
RHEA
Ensembl		 PMID:8392016 PMID:10640627 PMID:16262633 PMID:28216226 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta enables IEA
IBA
TAS		 Ensembl
GO_Central
TreeGrafter
RHEA
Reactome		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 Reactome:R-HSA-9658445 Reactome:R-HSA-9660536 Reactome:R-HSA-9660538 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma enables TAS
IBA
IEA
IMP		 (PMID:10880350), (PMID:17936702) Reactome
GO_Central
TreeGrafter
RHEA
UniProt
Ensembl		 PMID:10880350 PMID:17936702 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 Reactome:R-HSA-9658445 Reactome:R-HSA-9660536 Reactome:R-HSA-9660538 NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C enables TAS (PMID:8985175) PINC PMID:8985175 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PPP1R3D protein phosphatase 1 regulatory subunit 3D enables TAS (PMID:9414128) PINC PMID:9414128 NCBI chr20:59,936,663...59,940,305
Ensembl chr20:59,936,663...59,940,305 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha enables ISO
IEA
IBA
TAS
IDA
ISS		 (PMID:10640627), (PMID:16262633), (PMID:21131359), (PMID:28386764)
(PMID:25438055), (PMID:30513302), (PMID:30595372), (PMID:30611118)		 RGD
TreeGrafter
GO_Central
ARUK-UCL
InterPro
Ensembl
RHEA
UniProt		 PMID:10640627 PMID:16262633 PMID:16519540 PMID:18322138 PMID:21131359 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:1582610 RGD:8693423 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta enables ISO
IEA
IBA
TAS
ISS		 (PMID:10640627), (PMID:16262633), (PMID:8206937) RGD
TreeGrafter
GO_Central
InterPro
RHEA
Ensembl
ARUK-UCL		 PMID:8206937 PMID:10640627 PMID:11884620 PMID:16262633 PMID:16519540 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:1582610 RGD:729591 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314 		JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha enables IEA Ensembl GO_REF:0000107 NCBI chr19:52,190,052...52,229,518
Ensembl chr19:52,170,936...52,229,518 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha enables ISO
IEA
IDA
IMP
NAS		 (PMID:30718414)
(PMID:30611118)
(PMID:8392375)		 RGD
UniProt
RHEA
Ensembl		 PMID:8392375 PMID:12135494 PMID:30611118 PMID:30718414 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 RGD:729536 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta enables NAS
IEA		 (PMID:8392375) UniProt
RHEA
Ensembl		 PMID:8392375 GO_REF:0000107 GO_REF:0000116 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma enables IEA RHEA
UniProt		 GO_REF:0000116 GO_REF:0000117 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,142 		JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit enables IDA
IBA
IEA
NAS		 (PMID:20154705)
(PMID:9837938)		 UniProt
GO_Central
TreeGrafter
InterPro
RHEA
Ensembl		 PMID:9837938 PMID:20154705 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr16:30,075,994...30,085,376
Ensembl chr16:30,075,978...30,085,376 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit enables ISS
IBA
IEA
IDA
TAS		 (PMID:15546861)
(PMID:30699359)
(PMID:15546861), (PMID:16262633), (PMID:7925273)		 ARUK-UCL
GO_Central
RHEA
UniProt
Reactome		 PMID:7925273 PMID:15546861 PMID:16262633 PMID:30699359 GO_REF:0000033 GO_REF:0000116 Reactome:R-HSA-5675433 Reactome:R-HSA-5683405 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit enables ISO
IEA
IBA
TAS
IDA		 (PMID:9013334)
(PMID:16716191), (PMID:32474700)		 RGD
TreeGrafter
GO_Central
InterPro
RHEA
PINC
Ensembl
MGI		 PMID:8077208 PMID:9013334 PMID:16716191 PMID:32474700 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:68293 Reactome:R-HSA-5694421 NCBI chr 9:125,146,573...125,189,803
Ensembl chr 9:125,146,573...125,189,939 		JBrowse link
G PPTC7 protein phosphatase targeting COQ7 enables IMP
IBA
IEA		 (PMID:30267671) UniProt
GO_Central
RHEA		 PMID:30267671 GO_REF:0000033 GO_REF:0000116 NCBI chr12:110,533,245...110,583,318
Ensembl chr12:110,533,245...110,583,318 		JBrowse link
G PTEN phosphatase and tensin homolog enables IDA
IEA		 (PMID:9256433) UniProt
RHEA		 PMID:9256433 GO_REF:0000116 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 enables IEA RHEA GO_REF:0000116 NCBI chr11:47,565,599...47,573,461
Ensembl chr11:47,565,430...47,573,461 		JBrowse link
G RPAP2 RNA polymerase II associated protein 2 enables IEA
IDA		 (PMID:30118681) RHEA
UniProt		 PMID:30118681 GO_REF:0000116 NCBI chr 1:92,299,059...92,402,056
Ensembl chr 1:92,299,059...92,402,056 		JBrowse link
G SSH1 slingshot protein phosphatase 1 enables IEA RHEA GO_REF:0000116 NCBI chr12:108,778,191...108,857,583
Ensembl chr12:108,778,191...108,857,590 		JBrowse link
G SSH2 slingshot protein phosphatase 2 enables IEA RHEA GO_REF:0000116 NCBI chr17:29,625,938...29,930,228
Ensembl chr17:29,625,938...29,930,276 		JBrowse link
G SSH3 slingshot protein phosphatase 3 enables IEA RHEA GO_REF:0000116 NCBI chr11:67,303,530...67,312,592
Ensembl chr11:67,303,478...67,312,607 		JBrowse link
G SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase enables IEA RHEA
UniProt		 GO_REF:0000104 GO_REF:0000116 NCBI chr 1:1,541,673...1,574,863
Ensembl chr 1:1,541,673...1,574,863 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 enables IEA InterPro GO_REF:0000002 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060 		JBrowse link
G TIMM50 translocase of inner mitochondrial membrane 50 enables IDA
IEA		 (PMID:15044455) UniProt PMID:15044455 GO_REF:0000117 NCBI chr19:39,480,838...39,493,779
Ensembl chr19:39,480,412...39,493,785 		JBrowse link
G UBLCP1 ubiquitin like domain containing CTD phosphatase 1 enables IEA
IBA
IDA		 (PMID:21949367), (PMID:28539385) UniProt
GO_Central
RHEA		 PMID:21949367 PMID:28539385 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117 NCBI chr 5:159,263,290...159,286,036
Ensembl chr 5:159,263,290...159,286,036 		JBrowse link
[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDP1 pyruvate dehydrogenase phosphatase catalytic subunit 1 enables IEA
IBA
IDA		 (PMID:15554715) RHEA
GO_Central
TreeGrafter
UniProt		 PMID:15554715 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000118 NCBI chr 8:93,916,923...93,926,068
Ensembl chr 8:93,857,807...93,926,068 		JBrowse link
G PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 enables IEA
IBA
ISS		 RHEA
GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754 		JBrowse link
G PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H enables IBA GO_Central GO_REF:0000033 NCBI chr12:62,643,994...62,935,150
Ensembl chr12:62,643,994...62,935,150 		JBrowse link
G PPM1J protein phosphatase, Mg2+/Mn2+ dependent 1J enables IBA GO_Central GO_REF:0000033 NCBI chr 1:112,709,998...112,715,332
Ensembl chr 1:112,709,994...112,715,332 		JBrowse link
G PPM1M protein phosphatase, Mg2+/Mn2+ dependent 1M enables IBA GO_Central GO_REF:0000033 NCBI chr 3:52,245,759...52,250,599
Ensembl chr 3:52,245,759...52,250,599 		JBrowse link
calcium-dependent protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2G calcium/calmodulin dependent protein kinase II gamma enables NAS (PMID:9060999) UniProt PMID:9060999 NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591 		JBrowse link
G PPP2R3B protein phosphatase 2 regulatory subunit B''beta enables ISO (PMID:27998980) MGI PMID:27998980 NCBI chr  X:333,933...386,907
NCBI chr  Y:333,933...386,907
Ensembl chr  Y:333,933...386,955
Ensembl chr  X:333,933...386,955 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha enables ISO
IEA		 RGD
UniProt
Ensembl		 PMID:12135494 GO_REF:0000107 GO_REF:0000117 RGD:729536 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta enables ISO
IEA		 RGD
UniProt		 PMID:12135494 GO_REF:0000117 RGD:729536 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma enables IDA
IEA		 (PMID:26429887) MGI
UniProt		 PMID:26429887 GO_REF:0000117 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,142 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha enables NAS (PMID:2558868) UniProt PMID:2558868 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237 		JBrowse link
calmodulin-dependent protein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A enables IDA (PMID:11559703) UniProt PMID:11559703 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F enables IDA (PMID:11559703), (PMID:15140879) UniProt PMID:11559703 PMID:15140879 NCBI chr22:21,919,425...21,952,848
Ensembl chr22:21,919,425...21,952,848 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha enables IEA
IBA
IDA
IMP
TAS		 (PMID:18815128), (PMID:19154138), (PMID:23468591), (PMID:30718414)
(PMID:30254215)
(PMID:2556704)		 Ensembl
TreeGrafter
GO_Central
UniProt
InterPro		 PMID:2556704 PMID:18815128 PMID:19154138 PMID:23468591 PMID:30254215 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta enables ISS
IEA
IBA
IDA
TAS		 (PMID:19154138), (PMID:25720963), (PMID:26794871), (PMID:32753672)
(PMID:2556704)		 UniProt
TreeGrafter
GO_Central
Ensembl
InterPro		 PMID:2556704 PMID:19154138 PMID:25720963 PMID:26794871 PMID:32753672 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma enables IEA
IBA
IDA		 (PMID:19154138) InterPro
GO_Central
UniProt		 PMID:19154138 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,142 		JBrowse link
MAP kinase serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP4 dual specificity phosphatase 4 enables IDA (PMID:7535768) UniProt PMID:7535768 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
myosin phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC013717.1 novel protein, PPM1B-SLC3A1 readthrough enables IEA UniProt GO_REF:0000003 Ensembl chr 2:44,168,851...44,320,310 JBrowse link
G CDC14A cell division cycle 14A enables IEA UniProt GO_REF:0000003 NCBI chr 1:100,345,001...100,520,277
Ensembl chr 1:100,345,001...100,520,277 		JBrowse link
G CDC14B cell division cycle 14B enables IEA UniProt GO_REF:0000003 NCBI chr 9:96,490,939...96,619,843
Ensembl chr 9:96,490,241...96,619,843 		JBrowse link
G CDC14C cell division cycle 14C enables IEA UniProt GO_REF:0000003 NCBI chr 7:48,924,547...48,927,454
Ensembl chr 7:48,924,547...48,927,454 		JBrowse link
G CDKL3 cyclin dependent kinase like 3 enables IEA UniProt GO_REF:0000003 NCBI chr 5:134,283,345...134,371,624
Ensembl chr 5:134,286,350...134,371,047 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 enables IEA UniProt GO_REF:0000003 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CPPED1 calcineurin like phosphoesterase domain containing 1 enables IEA UniProt GO_REF:0000003 NCBI chr16:12,659,799...12,803,887
Ensembl chr16:12,659,799...12,803,887 		JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr17:7,243,591...7,251,978
Ensembl chr17:7,243,591...7,252,491 		JBrowse link
G CTDP1 CTD phosphatase subunit 1 enables IEA UniProt GO_REF:0000003 NCBI chr18:79,676,768...79,756,625
Ensembl chr18:79,679,803...79,754,503 		JBrowse link
G CTDSP1 CTD small phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr 2:218,396,351...218,405,941
Ensembl chr 2:218,397,136...218,405,941 		JBrowse link
G CTDSP2 CTD small phosphatase 2 enables IEA UniProt GO_REF:0000003 NCBI chr12:57,819,927...57,846,729
Ensembl chr12:57,819,927...57,846,729 		JBrowse link
G CTDSPL CTD small phosphatase like enables IEA UniProt GO_REF:0000003 NCBI chr 3:37,861,880...37,984,469
Ensembl chr 3:37,861,880...37,984,469 		JBrowse link
G DUSP1 dual specificity phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP10 dual specificity phosphatase 10 enables IEA UniProt GO_REF:0000003 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G DUSP12 dual specificity phosphatase 12 enables IEA UniProt GO_REF:0000003 NCBI chr 1:161,749,786...161,757,238
Ensembl chr 1:161,749,758...161,757,238 		JBrowse link
G DUSP13A dual specificity phosphatase 13A enables IEA UniProt GO_REF:0000003 NCBI chr10:75,105,669...75,109,157
Ensembl chr10:75,094,434...75,109,221 		JBrowse link
G DUSP13B dual specificity phosphatase 13B enables IEA UniProt GO_REF:0000003 NCBI chr10:75,094,434...75,109,191
Ensembl chr10:75,094,432...75,109,206
Ensembl chr10:75,094,432...75,109,206 		JBrowse link
G DUSP14 dual specificity phosphatase 14 enables IEA UniProt GO_REF:0000003 NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501 		JBrowse link
G DUSP15 dual specificity phosphatase 15 enables IEA UniProt GO_REF:0000003 NCBI chr20:31,845,593...31,870,664
Ensembl chr20:31,847,637...31,870,664 		JBrowse link
G DUSP16 dual specificity phosphatase 16 enables IEA UniProt GO_REF:0000003 NCBI chr12:12,473,282...12,562,863
Ensembl chr12:12,473,282...12,562,863 		JBrowse link
G DUSP18 dual specificity phosphatase 18 enables IEA UniProt GO_REF:0000003 NCBI chr22:30,652,051...30,667,875
Ensembl chr22:30,652,051...30,667,887 		JBrowse link
G DUSP19 dual specificity phosphatase 19 enables IEA UniProt GO_REF:0000003 NCBI chr 2:183,078,747...183,100,008
Ensembl chr 2:183,078,559...183,100,008 		JBrowse link
G DUSP2 dual specificity phosphatase 2 enables IEA UniProt GO_REF:0000003 NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,169...96,145,440 		JBrowse link
G DUSP21 dual specificity phosphatase 21 enables IEA UniProt GO_REF:0000003 NCBI chr  X:44,844,021...44,844,888
Ensembl chr  X:44,844,021...44,844,888 		JBrowse link
G DUSP22 dual specificity phosphatase 22 enables IEA UniProt GO_REF:0000003 NCBI chr 6:292,487...351,355
Ensembl chr 6:291,630...351,355 		JBrowse link
G DUSP23 dual specificity phosphatase 23 enables IEA UniProt GO_REF:0000003 NCBI chr 1:159,780,962...159,782,543
Ensembl chr 1:159,780,932...159,782,543 		JBrowse link
G DUSP26 dual specificity phosphatase 26 enables IEA UniProt GO_REF:0000003 NCBI chr 8:33,591,330...33,600,023
Ensembl chr 8:33,591,330...33,600,023 		JBrowse link
G DUSP28 dual specificity phosphatase 28 enables IEA UniProt GO_REF:0000003 NCBI chr 2:240,560,054...240,565,256
Ensembl chr 2:240,560,054...240,565,256 		JBrowse link
G DUSP29 dual specificity phosphatase 29 enables IEA UniProt GO_REF:0000003 NCBI chr10:75,037,472...75,073,642
Ensembl chr10:75,037,472...75,073,642 		JBrowse link
G DUSP3 dual specificity phosphatase 3 enables IEA UniProt GO_REF:0000003 NCBI chr17:43,766,125...43,778,977
Ensembl chr17:43,766,125...43,778,977 		JBrowse link
G DUSP4 dual specificity phosphatase 4 enables IEA UniProt GO_REF:0000003 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G DUSP5 dual specificity phosphatase 5 enables IEA UniProt GO_REF:0000003 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP6 dual specificity phosphatase 6 enables IEA UniProt GO_REF:0000003 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G DUSP7 dual specificity phosphatase 7 enables IEA UniProt GO_REF:0000003 NCBI chr 3:52,048,919...52,056,571
Ensembl chr 3:52,048,919...52,056,571 		JBrowse link
G DUSP8 dual specificity phosphatase 8 enables IEA UniProt GO_REF:0000003 NCBI chr11:1,554,051...1,572,848
Ensembl chr11:1,554,051...1,572,271 		JBrowse link
G DUSP9 dual specificity phosphatase 9 enables IEA UniProt GO_REF:0000003 NCBI chr  X:153,642,441...153,651,326
Ensembl chr  X:153,642,492...153,651,326 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin enables IEA UniProt GO_REF:0000003 NCBI chr 6:145,383,353...145,736,023
Ensembl chr 6:145,382,535...145,736,023 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr 8:71,197,433...71,548,094
Ensembl chr 8:71,197,433...71,592,025 		JBrowse link
G ILKAP ILK associated serine/threonine phosphatase enables IEA UniProt GO_REF:0000003 NCBI chr 2:238,170,402...238,203,695
Ensembl chr 2:238,170,402...238,203,708 		JBrowse link
G LOC124907782 dual specificity protein phosphatase 22 enables IEA UniProt GO_REF:0000003
G MYH3 myosin heavy chain 3 enables TAS Reactome Reactome:R-HSA-390593 NCBI chr17:10,628,532...10,678,417
Ensembl chr17:10,628,526...10,657,309 		JBrowse link
G MYH6 myosin heavy chain 6 enables TAS Reactome Reactome:R-HSA-390593 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273 		JBrowse link
G MYH8 myosin heavy chain 8 enables TAS Reactome Reactome:R-HSA-390593 NCBI chr17:10,390,322...10,421,950
Ensembl chr17:10,390,322...10,421,950 		JBrowse link
G PDXP pyridoxal phosphatase enables IEA UniProt GO_REF:0000003 NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932 		JBrowse link
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase enables IEA UniProt GO_REF:0000003 NCBI chr12:132,710,842...132,722,734
Ensembl chr12:132,710,819...132,722,734 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr18:62,715,541...62,980,433
Ensembl chr18:62,715,541...62,980,433 		JBrowse link
G PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 enables IEA UniProt GO_REF:0000003 NCBI chr16:71,644,924...71,724,701
Ensembl chr16:71,637,835...71,724,701 		JBrowse link
G PPEF1 protein phosphatase with EF-hand domain 1 enables IEA UniProt GO_REF:0000003 NCBI chr  X:18,675,067...18,827,917
Ensembl chr  X:18,675,909...18,827,921 		JBrowse link
G PPEF2 protein phosphatase with EF-hand domain 2 enables IEA UniProt GO_REF:0000003 NCBI chr 4:75,859,867...75,902,452
Ensembl chr 4:75,859,864...75,902,571 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A enables IEA UniProt GO_REF:0000003 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B enables IEA UniProt GO_REF:0000003 NCBI chr 2:44,168,875...44,246,928
Ensembl chr 2:44,167,969...44,244,384 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D enables IEA UniProt GO_REF:0000003 NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280 		JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E enables IEA UniProt GO_REF:0000003 NCBI chr17:58,755,854...58,985,179
Ensembl chr17:58,755,854...58,985,179 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F enables IEA UniProt GO_REF:0000003 NCBI chr22:21,919,425...21,952,848
Ensembl chr22:21,919,425...21,952,848 		JBrowse link
G PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G enables IEA UniProt GO_REF:0000003 NCBI chr 2:27,381,199...27,409,591
Ensembl chr 2:27,381,195...27,409,591 		JBrowse link
G PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H enables IEA UniProt GO_REF:0000003 NCBI chr12:62,643,994...62,935,150
Ensembl chr12:62,643,994...62,935,150 		JBrowse link
G PPM1J protein phosphatase, Mg2+/Mn2+ dependent 1J enables IEA UniProt GO_REF:0000003 NCBI chr 1:112,709,998...112,715,332
Ensembl chr 1:112,709,994...112,715,332 		JBrowse link
G PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K enables IEA UniProt GO_REF:0000003 NCBI chr 4:88,257,620...88,284,561
Ensembl chr 4:88,257,620...88,284,769 		JBrowse link
G PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L enables IEA UniProt GO_REF:0000003 NCBI chr 3:160,756,231...161,078,902
Ensembl chr 3:160,755,602...161,078,902 		JBrowse link
G PPM1M protein phosphatase, Mg2+/Mn2+ dependent 1M enables IEA UniProt GO_REF:0000003 NCBI chr 3:52,245,759...52,250,599
Ensembl chr 3:52,245,759...52,250,599 		JBrowse link
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) enables IEA UniProt GO_REF:0000003 NCBI chr19:45,498,443...45,502,513
Ensembl chr19:45,488,777...45,502,513 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha enables IEA UniProt GO_REF:0000003 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta enables ISS
IEA		 UniProt GO_REF:0000003 GO_REF:0000024 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma enables IEA UniProt GO_REF:0000003 NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha enables IEA UniProt GO_REF:0000003 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta enables IEA UniProt GO_REF:0000003 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha enables IEA UniProt GO_REF:0000003 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta enables IEA UniProt GO_REF:0000003 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma enables IEA UniProt GO_REF:0000003 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,142 		JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit enables IEA UniProt GO_REF:0000003 NCBI chr16:30,075,994...30,085,376
Ensembl chr16:30,075,978...30,085,376 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit enables IEA UniProt GO_REF:0000003 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit enables IEA UniProt GO_REF:0000003 NCBI chr 9:125,146,573...125,189,803
Ensembl chr 9:125,146,573...125,189,939 		JBrowse link
G PPTC7 protein phosphatase targeting COQ7 enables IEA UniProt GO_REF:0000003 NCBI chr12:110,533,245...110,583,318
Ensembl chr12:110,533,245...110,583,318 		JBrowse link
G PTEN phosphatase and tensin homolog enables IEA UniProt GO_REF:0000003 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 enables IEA UniProt GO_REF:0000003 NCBI chr11:47,565,599...47,573,461
Ensembl chr11:47,565,430...47,573,461 		JBrowse link
G RPAP2 RNA polymerase II associated protein 2 enables IEA UniProt GO_REF:0000003 NCBI chr 1:92,299,059...92,402,056
Ensembl chr 1:92,299,059...92,402,056 		JBrowse link
G SSH1 slingshot protein phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr12:108,778,191...108,857,583
Ensembl chr12:108,778,191...108,857,590 		JBrowse link
G SSH2 slingshot protein phosphatase 2 enables IEA UniProt GO_REF:0000003 NCBI chr17:29,625,938...29,930,228
Ensembl chr17:29,625,938...29,930,276 		JBrowse link
G SSH3 slingshot protein phosphatase 3 enables IEA UniProt GO_REF:0000003 NCBI chr11:67,303,530...67,312,592
Ensembl chr11:67,303,478...67,312,607 		JBrowse link
G SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase enables IEA UniProt GO_REF:0000003 NCBI chr 1:1,541,673...1,574,863
Ensembl chr 1:1,541,673...1,574,863 		JBrowse link
G SSU72L1 SSU72 like 1 enables IEA UniProt GO_REF:0000003 NCBI chr11:4,338,245...4,339,345
Ensembl chr11:4,338,245...4,339,345 		JBrowse link
G SSU72L2 SSU72 like 2 enables IEA UniProt GO_REF:0000003 NCBI chr11:4,241,641...4,242,706
Ensembl chr11:4,241,641...4,242,706 		JBrowse link
G SSU72L3 SSU72 like 3 enables IEA UniProt GO_REF:0000003 NCBI chr11:4,329,790...4,330,864
Ensembl chr11:4,329,790...4,330,864 		JBrowse link
G SSU72L4 SSU72 like 4 enables IEA UniProt GO_REF:0000003 NCBI chr11:4,287,084...4,288,185
Ensembl chr11:4,287,084...4,288,185 		JBrowse link
G SSU72L5 SSU72 like 5 enables IEA UniProt GO_REF:0000003 NCBI chr11:4,233,217...4,234,287
Ensembl chr11:4,233,217...4,234,287 		JBrowse link
G SSU72L6 SSU72 like 6 enables IEA UniProt GO_REF:0000003 NCBI chr 7:124,476,317...124,477,664
Ensembl chr 7:124,476,317...124,477,664 		JBrowse link
G UBLCP1 ubiquitin like domain containing CTD phosphatase 1 enables IEA UniProt GO_REF:0000003 NCBI chr 5:159,263,290...159,286,036
Ensembl chr 5:159,263,290...159,286,036 		JBrowse link
RNA polymerase II CTD heptapeptide repeat phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTDP1 CTD phosphatase subunit 1 enables IDA
IBA
IEA		 (PMID:12721286), (PMID:9765293) GO_Central
InterPro
UniProt		 PMID:9765293 PMID:12721286 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr18:79,676,768...79,756,625
Ensembl chr18:79,679,803...79,754,503 		JBrowse link
G CTDSP1 CTD small phosphatase 1 enables IDA
IBA
IEA		 (PMID:12721286) UniProt
GO_Central
InterPro		 PMID:12721286 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:218,396,351...218,405,941
Ensembl chr 2:218,397,136...218,405,941 		JBrowse link
G CTDSP2 CTD small phosphatase 2 enables IDA
IBA
IEA		 (PMID:12721286) UniProt
GO_Central
InterPro		 PMID:12721286 GO_REF:0000002 GO_REF:0000033 NCBI chr12:57,819,927...57,846,729
Ensembl chr12:57,819,927...57,846,729 		JBrowse link
G CTDSPL CTD small phosphatase like enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:37,861,880...37,984,469
Ensembl chr 3:37,861,880...37,984,469 		JBrowse link
G CTDSPL2 CTD small phosphatase like 2 enables IDA (PMID:26920047) CACAO PMID:26920047 NCBI chr15:44,427,629...44,529,038
Ensembl chr15:44,427,622...44,529,038 		JBrowse link
G RPAP2 RNA polymerase II associated protein 2 enables IEA
IBA
IMP		 (PMID:22137580) InterPro
GO_Central
UniProt		 PMID:22137580 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:92,299,059...92,402,056
Ensembl chr 1:92,299,059...92,402,056 		JBrowse link
G RPRD1A regulation of nuclear pre-mRNA domain containing 1A enables IEA UniProt GO_REF:0000104 NCBI chr18:35,989,824...36,067,559
Ensembl chr18:35,984,387...36,067,576 		JBrowse link
G RPRD1B regulation of nuclear pre-mRNA domain containing 1B enables IEA UniProt GO_REF:0000104 NCBI chr20:38,033,746...38,092,364
Ensembl chr20:38,033,725...38,127,780 		JBrowse link
G SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase enables IDA
IBA
IEA		 (PMID:20861839) UniProt
GO_Central
TreeGrafter		 PMID:20861839 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:1,541,673...1,574,863
Ensembl chr 1:1,541,673...1,574,863 		JBrowse link
G SSU72L1 SSU72 like 1 enables IBA GO_Central GO_REF:0000033 NCBI chr11:4,338,245...4,339,345
Ensembl chr11:4,338,245...4,339,345 		JBrowse link
G SSU72L2 SSU72 like 2 enables IBA GO_Central GO_REF:0000033 NCBI chr11:4,241,641...4,242,706
Ensembl chr11:4,241,641...4,242,706 		JBrowse link
G SSU72L3 SSU72 like 3 enables IBA GO_Central GO_REF:0000033 NCBI chr11:4,329,790...4,330,864
Ensembl chr11:4,329,790...4,330,864 		JBrowse link
G SSU72L4 SSU72 like 4 enables IBA GO_Central GO_REF:0000033 NCBI chr11:4,287,084...4,288,185
Ensembl chr11:4,287,084...4,288,185 		JBrowse link
G SSU72L5 SSU72 like 5 enables IBA GO_Central GO_REF:0000033 NCBI chr11:4,233,217...4,234,287
Ensembl chr11:4,233,217...4,234,287 		JBrowse link
G SSU72L6 SSU72 like 6 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:124,476,317...124,477,664
Ensembl chr 7:124,476,317...124,477,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19566
    catalytic activity 5977
      catalytic activity, acting on a protein 2452
        phosphoprotein phosphatase activity 194
          protein serine/threonine phosphatase activity 112
            MAP kinase serine/threonine phosphatase activity 1
            RNA polymerase II CTD heptapeptide repeat phosphatase activity + 15
            [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity 5
            calcium-dependent protein serine/threonine phosphatase activity + 8
            myosin phosphatase activity 87
Path 2
Term Annotations click to browse term
  molecular_function 19566
    catalytic activity 5977
      hydrolase activity 2627
        hydrolase activity, acting on ester bonds 844
          phosphoric ester hydrolase activity 395
            phosphatase activity 298
              phosphoprotein phosphatase activity 194
                protein serine/threonine phosphatase activity 112
                  MAP kinase serine/threonine phosphatase activity 1
                  RNA polymerase II CTD heptapeptide repeat phosphatase activity + 15
                  [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity 5
                  calcium-dependent protein serine/threonine phosphatase activity + 8
                  myosin phosphatase activity 87
paths to the root