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ONTOLOGY REPORT - ANNOTATIONS

Term:protein-lysine 6-oxidase activity
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Accession:GO:0004720 term browser browse the term
Definition:Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.
Synonyms:related_synonym: lysyl oxidase activity;   protein-L-lysine:oxygen 6-oxidoreductase (deaminating)
 alt_id: GO:0018056
 xref: EC:1.4.3.13;   MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN;   RHEA:24544;   reactome:R-HSA-2002466 "Formation of allysine by LOX";   reactome:R-HSA-2129375 "Elastin cross-linking by lysyl oxidase";   reactome:R-HSA-2395340 "Formation of hydroxyallysine by LOX"


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protein-lysine 6-oxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase enables IDA
ISO
IBA
IMP		 (PMID:14140), (PMID:14741400), (PMID:16192629), (PMID:20889), (PMID:27432961)
GO_REF:0000033
(PMID:31152061)		 RGD
GO_Central		 PMID:14140 PMID:20889 PMID:14741400 PMID:16192629 PMID:27432961 More... GO_REF:0000033, RGD:1600668, RGD:1600669 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Loxl1 lysyl oxidase-like 1 enables IBA
ISO		 GO_REF:0000033
(PMID:14745449)		 GO_Central
RGD		 PMID:14745449 GO_REF:0000033 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
G Loxl2 lysyl oxidase-like 2 enables IEA
IBA
ISS
ISO		 GO_REF:0000003
GO_REF:0000033
GO_REF:0000024
GO_REF:0000116
(PMID:23319596), (PMID:25959397), (PMID:27735137), (PMID:29581294)		 UniProt
GO_Central
RHEA
RGD		 PMID:23319596 PMID:25959397 PMID:27735137 PMID:29581294 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Loxl3 lysyl oxidase-like 3 enables ISO
IBA		 (PMID:28065600)
GO_REF:0000033
(PMID:26954549)		 RGD
GO_Central		 PMID:26954549 PMID:28065600 GO_REF:0000033 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Loxl4 lysyl oxidase-like 4 enables ISO
IBA		 (PMID:14551188)
(PMID:11292829)
GO_REF:0000033		 RGD
GO_Central		 PMID:11292829 PMID:14551188 GO_REF:0000033 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a protein 2509
        protein-lysine 6-oxidase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on the CH-NH2 group of donors 27
          oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 24
            diamine oxidase activity 9
              protein-lysine 6-oxidase activity 5
paths to the root