Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
go back to main search page
Accession:GO:0004671 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.
Synonyms:exact_synonym: S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity;   S-farnesylcysteine methyltransferase activity;   farnesyl cysteine C-terminal methyltransferase activity;   farnesyl-protein carboxymethyltransferase activity;   farnesylated protein C-terminal O-methyltransferase activity;   isoprenylated protein methyltransferase activity;   prenylated protein carboxyl methyltransferase activity;   prenylated protein methyltransferase activity;   prenylcysteine carboxylmethyltransferase activity;   prenylcysteine carboxymethyltransferase activity;   prenylcysteine methyltransferase activity;   protein C-terminal farnesylcysteine O-methyltransferase activity;   protein S-farnesylcysteine C-terminal methyltransferase activity;   protein-S-isoprenylcysteine O-methyltransferase activity
 related_synonym: isoprenylcysteine carboxylmethyltransferase activity;   prenylcysteine carboxyl methyltransferase activity
 alt_id: GO:0018225
 xref: EC:2.1.1.100;   KEGG_REACTION:R04496;   MetaCyc:2.1.1.100-RXN;   reactome:R-HSA-6788650 "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins"


show annotations for term's descendants       view all columns           Sort by:
 
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icmt isoprenylcysteine carboxyl methyltransferase JBrowse link 4 152,297,214 152,307,126 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 22376
    catalytic activity 5700
      catalytic activity, acting on a protein 2178
        protein methyltransferase activity 87
          protein carboxyl O-methyltransferase activity 7
            protein C-terminal carboxyl O-methyltransferase activity 3
              protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 22376
    catalytic activity 5700
      transferase activity 2255
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            O-methyltransferase activity 23
              carboxyl-O-methyltransferase activity 7
                protein carboxyl O-methyltransferase activity 7
                  protein C-terminal carboxyl O-methyltransferase activity 3
                    protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.