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ONTOLOGY REPORT - ANNOTATIONS

Term:porphobilinogen synthase activity
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Accession:GO:0004655 term browser browse the term
Definition:Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.
Synonyms:exact_synonym: aminolevulinate dehydratase activity;   delta-aminolevulinic acid dehydratase activity
 related_synonym: 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing);   5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming);   5-levulinic acid dehydratase activity;   aminolevulinic dehydratase activity;   delta-aminolevulinate dehydratase activity;   delta-aminolevulinic acid dehydrase activity;   delta-aminolevulinic dehydratase activity
 xref: EC:4.2.1.24;   KEGG_REACTION:R00036;   MetaCyc:PORPHOBILSYNTH-RXN;   RHEA:24064;   reactome:R-HSA-189439 "ALAD condenses 2 dALAs to form PBG"

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porphobilinogen synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase enables ISO (PMID:11032836), (PMID:8175643)
(PMID:14050799), (PMID:4959158), (PMID:4981581)
(PMID:5393940)		 RGD
CAFA
MGI		 PMID:4959158 PMID:4981581 PMID:5393940 PMID:8175643 PMID:11032836 More... RGD:4144201 NCBI chrNW_004955419:14,093,010...14,104,376
Ensembl chrNW_004955419:14,093,010...14,104,545 		JBrowse link
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  molecular_function 14224
    catalytic activity 3718
      lyase activity 141
        carbon-oxygen lyase activity 55
          hydro-lyase activity 43
            porphobilinogen synthase activity 1
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