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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphopyruvate hydratase activity
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Accession:GO:0004634 term browser browse the term
Definition:Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
Synonyms:exact_synonym: 2-phospho-D-glycerate-hydrolase activity
 narrow_synonym: nervous-system specific enolase
 related_synonym: 14-3-2-protein;   2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming);   2-phospho-D-glycerate hydro-lyase activity;   2-phosphoglycerate dehydratase activity;   2-phosphoglycerate enolase activity;   2-phosphoglyceric dehydratase activity;   enolase activity;   gamma-enolase activity;   phosphoenolpyruvate hydratase activity
 xref: EC:4.2.1.11;   MetaCyc:2PGADEHYDRAT-RXN;   RHEA:10164;   Reactome:R-HSA-70494 "Enolase dimers (ENO1,2,3) convert PEP to 2PG";   reactome:R-HSA-71660 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O"


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phosphopyruvate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 enables IEA
IBA		 UniProt
InterPro
Ensembl
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G ENO2 enolase 2 enables IEA
ISO
IBA		 InterPro
UniProt
RGD
TreeGrafter
GO_Central		 PMID:15720133 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 RGD:2302795 NCBI chr 5:63,799,927...63,809,067
Ensembl chr 5:63,799,930...63,809,410 		JBrowse link
G ENO3 enolase 3 enables ISO
IEA
IBA		 RGD
UniProt
RHEA
InterPro
Ensembl
TreeGrafter
GO_Central		 PMID:8594891 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:2301765 NCBI chr12:51,954,614...51,959,991
Ensembl chr12:51,954,613...51,961,496 		JBrowse link
G ENO4 enolase 4 enables IEA
IBA		 InterPro
UniProt
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr14:127,032,217...127,063,660
Ensembl chr14:127,036,991...127,066,048 		JBrowse link
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Term Annotations click to browse term
  molecular_function 18689
    catalytic activity 5662
      lyase activity 202
        carbon-oxygen lyase activity 80
          hydro-lyase activity 60
            phosphopyruvate hydratase activity 4
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