ONTOLOGY REPORT - ANNOTATIONS
Term: tRNA-specific ribonuclease activity
Accession: GO:0004549
browse the term
Definition: Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
Synonyms: exact_synonym: tRNA-specific RNase activity
xref: reactome:R-HSA-5696813 "TSEN complex cleaves the intron from pre-tRNA"; reactome:R-HSA-5696815 "ELAC2 cleaves the 3' end of pre-tRNA"; reactome:R-HSA-6785722 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript"; reactome:R-HSA-6786854 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript"
G
Ang
angiogenin
enables
ISO
(PMID:19332886), (PMID:20129916), (PMID:21855800), (PMID:27518564), (PMID:29100074), (PMID:29748193), (PMID:31582561), (PMID:32510170), (PMID:38718836) (PMID:24752898), (PMID:33986151)
RGD
PMID:19332886 PMID:20129916 PMID:21855800 PMID:24752898 PMID:27518564 PMID:29100074 PMID:29748193 PMID:31582561 PMID:32510170 PMID:33986151 PMID:38718836 More...
NCBI chr15:26,786,233...26,796,883
G
Elac1
elaC ribonuclease Z 1
enables
ISO
(PMID:32075755)
RGD
PMID:32075755
NCBI chr18:67,321,231...67,341,358
Ensembl chr18:67,323,583...67,340,936
G
Elac2
elaC ribonuclease Z 2
enables
ISO
(PMID:12711671), (PMID:15317868), (PMID:16361254), (PMID:18809514), (PMID:21559454), (PMID:21593607)
RGD
PMID:12711671 PMID:15317868 PMID:16361254 PMID:18809514 PMID:21559454 PMID:21593607 More...
NCBI chr10:50,131,449...50,154,755
Ensembl chr10:49,632,378...49,655,614
G
Pop1
POP1 homolog, ribonuclease P/MRP subunit
contributes_to
ISO
(PMID:30454648), (PMID:8918471)
RGD
PMID:8918471 PMID:30454648
NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:65,705,368...65,733,141
G
Pop4
POP4 homolog, ribonuclease P/MRP subunit
contributes_to
ISS ISO
GO_REF:0000024 (PMID:30454648)
UniProt RGD
PMID:30454648
GO_REF:0000024
NCBI chr 1:100,096,722...100,105,056
Ensembl chr 1:90,960,022...90,968,443
G
Pop5
POP5 homolog, ribonuclease P/MRP subunit
contributes_to enables
ISO
(PMID:30454648) (PMID:11413139)
RGD
PMID:11413139 PMID:30454648
NCBI chr12:47,037,451...47,045,778
Ensembl chr12:41,376,755...41,381,336
G
Pop7
POP7 homolog, ribonuclease P/MRP subunit
contributes_to
ISO
(PMID:30454648)
RGD
PMID:30454648
NCBI chr12:24,826,161...24,827,202
Ensembl chr12:19,189,138...19,190,674
G
Prorp
protein only RNase P catalytic subunit
enables
ISS IBA ISO
GO_REF:0000024 GO_REF:0000033 (PMID:25953853)
UniProt GO_Central RGD
PMID:25953853
GO_REF:0000024 GO_REF:0000033
NCBI chr 6:78,404,821...78,497,562
Ensembl chr 6:72,670,847...72,762,416
G
Rpp14
ribonuclease P/MRP subunit p14
contributes_to
ISO
(PMID:30454648)
RGD
PMID:30454648
NCBI chr15:16,837,796...16,847,970
Ensembl chr15:16,836,859...16,852,101 Ensembl chr15:16,836,859...16,852,101
G
Rpp21
ribonuclease P/MRP subunit p21
contributes_to
ISO
(PMID:30454648)
RGD
PMID:30454648
NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106
G
Rpp25
ribonuclease P and MRP subunit p25
contributes_to
ISS ISO
GO_REF:0000024 (PMID:30454648)
UniProt RGD
PMID:30454648
GO_REF:0000024
NCBI chr 8:66,803,262...66,804,642
Ensembl chr 8:57,907,352...57,908,732
G
Rpp30
ribonuclease P/MRP subunit p30
contributes_to
ISO
(PMID:30454648)
RGD
PMID:30454648
NCBI chr 1:233,786,048...233,808,958
Ensembl chr 1:233,786,099...233,808,952
G
Rpp38
ribonuclease P/MRP subunit p38
contributes_to
ISO IBA
(PMID:30454648) GO_REF:0000033
RGD GO_Central
PMID:30454648
GO_REF:0000033
NCBI chr17:79,823,237...79,826,908
Ensembl chr17:74,908,932...74,927,431
G
Rpp40
ribonuclease P/MRP subunit p40
contributes_to enables
ISO IBA IEA
(PMID:30454648) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:30454648
GO_REF:0000033 GO_REF:0000107
NCBI chr17:29,153,203...29,162,241
Ensembl chr17:28,947,734...28,956,788
G
Tsen2
tRNA splicing endonuclease subunit 2
enables
IEA IBA
GO_REF:0000002 GO_REF:0000033
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr 4:150,275,389...150,310,846
Ensembl chr 4:148,602,863...148,638,215
G
Tsen34
tRNA splicing endonuclease subunit 34
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:74,432,687...74,440,553
Ensembl chr 1:65,517,330...65,524,412
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all