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ONTOLOGY REPORT - ANNOTATIONS


Term:ribonuclease A activity
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Accession:GO:0004522 term browser browse the term
Definition:Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
Synonyms:exact_synonym: RNase A activity;   RNase I activity;   alkaline ribonuclease activity;   ceratitis capitata alkaline ribonuclease activity;   pancreatic RNase activity;   ribonuclease I activity;   ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity;   ribonucleic phosphatase activity
 narrow_synonym: pancreatic ribonuclease activity" [] {comment="EC:4.6.1.18
 broad_synonym: RNase activity
 related_synonym: S-genotype-assocd. glycoproteins;   SLSG glycoproteins;   endoribonuclease I;   gene S glycoproteins;   gene S locus-specific glycoproteins
 xref: EC:4.6.1.18;   MetaCyc:3.1.27.5-RXN;   Wikipedia:Ribonuclease_A


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ribonuclease A activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC103690354 ribonuclease pancreatic beta-type JBrowse link 15 28,073,963 28,075,677 RGD:1600115
G LOC103694852 ribonuclease K6-like RGD:1624291
G LOC103694853 ribonuclease pancreatic gamma-type RGD:1600115
G Rnase1 ribonuclease A family member 1, pancreatic RGD:1600115
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 (pancreatic) JBrowse link 15 28,043,491 28,045,098 RGD:1600115
G Rnase1l2 ribonuclease, RNase A family, 1-like 2 (pancreatic) JBrowse link 15 28,127,147 28,128,797 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      catalytic activity, acting on RNA 357
        ribonuclease activity 121
          endoribonuclease activity 63
            endoribonuclease activity, producing 3'-phosphomonoesters 11
              ribonuclease A activity 6
Path 2
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 782
          nuclease activity 212
            endonuclease activity 121
              endoribonuclease activity 63
                endoribonuclease activity, producing 3'-phosphomonoesters 11
                  ribonuclease A activity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.